There are 3 ways to get from Iowa City to Missouri by bus (Greyhound), car, bus, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Iowa City to Des Moinesbus Greyhound US0123S / ...
- Take the bus from Des Moines to Kansas Citybus Jefferson 803 / ...
6h 35m$68–108Drive 303.7 mi
cheapest- Drive from Iowa City to Kansas Citycar 303.7 mi
5h 8m$56–80Bus, fly
- Take the bus from Iowa City to Chicago Bus Stationbus
- Fly from Chicago Midway International Airport (MDW) to Lambert–St. Louis International Airport (STL)plane MDW - STL
8h 37m$124–628
Chicago Midway International Airport (MDW) to Lambert–St. Louis International Airport (STL) flights
Questions & Answers
The cheapest way to get from Iowa City to Missouri is to drive which costs $55 - $80 and takes 5h 8m.
The fastest way to get from Iowa City to Missouri is to drive which takes 5h 8m and costs $55 - $80.
No, there is no direct bus from Iowa City to Missouri. However, there are services departing from Iowa City and arriving at Kansas City via Des Moines. The journey, including transfers, takes approximately 6h 35m.
The distance between Iowa City and Missouri is 310 miles. The road distance is 305.4 miles.
The best way to get from Iowa City to Missouri without a car is to bus which takes 6h 35m and costs $65 - $110.
It takes approximately 6h 35m to get from Iowa City to Missouri, including transfers.
Iowa City to Missouri bus services, operated by Greyhound USA, depart from Iowa City station.
Iowa City to Missouri bus services, operated by Greyhound USA, arrive at Des Moines station.
Yes, the driving distance between Iowa City to Missouri is 305 miles. It takes approximately 5h 8m to drive from Iowa City to Missouri.
There are 341+ hotels available in Missouri.
What companies run services between Iowa City, IA, USA and Missouri, USA?
You can take a bus from Iowa City to Kansas City via Des Moines in around 6h 35m.
- Website
- southwest.com
Flights from Chicago Midway International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 11m
- When
- Every day
- Estimated price
- $80–550
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Iowa City to Des Moines
- Ave. Duration
- 2h 5m
- Frequency
- Twice daily
- Estimated price
- $18–35
- Website
- https://www.greyhound.com/
Bus from Iowa City to Chicago Bus Station
- Ave. Duration
- 4h 45m
- Frequency
- Twice daily
- Estimated price
- $35–70
- Website
- https://www.greyhound.com/
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Des Moines to Kansas City
- Ave. Duration
- 3h 30m
- Frequency
- Twice daily
- Estimated price
- $50–75
- Book at
- https://www.jeffersonlines.com
- Adult
- $50–75
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide





