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How to get fromIowa City to Panama Cityby bus, plane, or car

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There are 5 ways to get from Iowa City to Panama City by bus, plane, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Quad City International Airport, fly to Northwest Florida Beaches International Airport

    best
    1. Take the bus from Iowa City to Moline Center Stationbus bus
    2. Fly from Quad City International Airport (MLI) to Northwest Florida Beaches International Airport (ECP)plane plane MLI - ECP
    8h 14m
    $160–528

  2. Drive 985.9 mi

    1. Drive from Iowa City to Panama Citycar car 985.9 mi
    17h 55m
    $180–260

  3. Bus to The Eastern Iowa Airport, fly to Northwest Florida Beaches International Airport

    1. Take the bus from Court St Transportation Center to GTC Bay 9bus bus
    2. Fly from The Eastern Iowa Airport (CID) to Northwest Florida Beaches International Airport (ECP)plane plane CID - ECP
    8h 32m

  4. Bus to The Eastern Iowa Airport, fly to Destin–Fort Walton Beach Airport, drive

    1. Take the bus from Court St Transportation Center to GTC Bay 9bus bus
    2. Fly from The Eastern Iowa Airport (CID) to Destin–Fort Walton Beach Airport (VPS)plane plane CID - VPS
    3. Drive from Destin–Fort Walton Beach Airport (VPS) to Panama Citycar car
    9h 38m

  5. Bus to Chicago O'Hare International Airport, fly to Northwest Florida Beaches International Airport

    1. Take the bus from Iowa City to Chicago Bus Stationbus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Northwest Florida Beaches International Airport (ECP)plane plane ORD - ECP
    9h 55m
    $175–548

Quad City International Airport (MLI) to Northwest Florida Beaches International Airport (ECP) flights

Calendar57Weekly Planes
Duration5h 51mAverage Duration
Ticket$85Cheapest Price
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Questions & Answers

Map of how to get from Iowa City to Panama City.ExpandLaunch map view
  • Distance: 899.5 mi
  • Duration: 8h 14m

What companies run services between Iowa City, IA, USA and Panama City, FL, USA?

There is no direct connection from Iowa City to Panama City. However, you can take the bus to Moline Center Station, walk to Centre Station, take the line 20 bus to QC Airport Shelter, walk to Quad City International Airport (MLI) airport, fly to Northwest Florida Beaches International Airport (ECP), then take the taxi to Panama City. Alternatively, you can drive from Iowa City to Panama City in around 17h 55m.

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