There are 5 ways to get from Iowa City to Sioux City by bus (Greyhound), car, bus, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Iowa City to Omaha, NEbus Greyhound US0123S
- Take the bus from Omaha to Sioux Citybus Jefferson Lines 705
7h 40m$76–112Drive 291.1 mi
cheapest- Drive from Iowa City to Sioux Citycar 291.1 mi
5h 7m$50–72Bus to Quad City International Airport, fly to Sioux Gateway Airport/Col. Bud Day Field
- Take the bus from Iowa City to Moline Center Stationbus
- Fly from Quad City International Airport (MLI) to Sioux Gateway Airport/Col. Bud Day Field (SUX)plane MLI - SUX
10h 24m$98–413Bus to The Eastern Iowa Airport, fly to Sioux Gateway Airport/Col. Bud Day Field
- Take the bus from Court St Transportation Center to GTC Bay 9bus
- Fly from The Eastern Iowa Airport (CID) to Sioux Gateway Airport/Col. Bud Day Field (SUX)plane CID - SUX
7h 39mBus to The Eastern Iowa Airport, fly to Sioux Falls, bus
- Take the bus from Court St Transportation Center to GTC Bay 9bus
- Fly from The Eastern Iowa Airport (CID) to Sioux Falls (FSD)plane CID - FSD
- Take the bus from Sioux Falls to Sioux Citybus
10h 22m
Iowa City to Sioux City by bus
Comparing Your Travel Options
The cheapest way to get from Iowa City to Sioux City is to drive which costs $45 - $75 and takes 5h 7m.
The fastest way to get from Iowa City to Sioux City is to drive which takes 5h 7m and costs $45 - $75.
No, there is no direct bus from Iowa City to Sioux City. However, there are services departing from Iowa City and arriving at Sioux City via Omaha. The journey, including transfers, takes approximately 7h 40m.
The distance between Iowa City and Sioux City is 351 miles. The road distance is 292.8 miles.
The best way to get from Iowa City to Sioux City without a car is to bus which takes 7h 40m and costs $75 - $120.
It takes approximately 7h 40m to get from Iowa City to Sioux City, including transfers.
Iowa City to Sioux City bus services, operated by Greyhound USA, depart from Iowa City station.
Iowa City to Sioux City bus services, operated by Greyhound USA, arrive at Omaha, NE station.
Yes, the driving distance between Iowa City to Sioux City is 293 miles. It takes approximately 5h 7m to drive from Iowa City to Sioux City.
Book your Iowa City to Sioux City bus tickets online with Omio.
What companies run services between Iowa City, IA, USA and Sioux City, IA, USA?
You can take a bus from Iowa City to Sioux City via Omaha in around 7h 40m.
- Website
- united.com
Flights from Quad City International Airport to Sioux Gateway Airport/Col. Bud Day Field via Chicago O'Hare
- Ave. Duration
- 7h 10m
- When
- Every day
- Estimated price
- $65–370
Flights from Quad City International Airport to Sioux Gateway Airport/Col. Bud Day Field via Chicago O'Hare, Denver
- Ave. Duration
- 9h 12m
- When
- Every day
- Estimated price
- $110–550
Flights from The Eastern Iowa Airport to Sioux Gateway Airport/Col. Bud Day Field via Denver
- Ave. Duration
- 5h 38m
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $95–480
Flights from The Eastern Iowa Airport to Sioux Gateway Airport/Col. Bud Day Field via Chicago O'Hare
- Ave. Duration
- 5h 41m
- When
- Every day
- Estimated price
- $65–380
Flights from The Eastern Iowa Airport to Sioux Falls via Chicago O'Hare
- Ave. Duration
- 5h 45m
- When
- Every day
- Estimated price
- $70–390
Flights from The Eastern Iowa Airport to Sioux Falls via Denver
- Ave. Duration
- 6h 25m
- When
- Every day
- Estimated price
- $100–480
- Website
- aa.com
Flights from The Eastern Iowa Airport to Sioux Falls via Chicago O'Hare
- Ave. Duration
- 5h 54m
- When
- Every day
- Estimated price
- $70–390
Flights from The Eastern Iowa Airport to Sioux Falls via Dallas/Ft.Worth
- Ave. Duration
- 6h 55m
- When
- Every day
- Estimated price
- $110–550
- Website
- delta.com
Flights from The Eastern Iowa Airport to Sioux Falls via Minneapolis
- Ave. Duration
- 5h 1m
- When
- Every day
- Estimated price
- $55–350
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Iowa City to Omaha, NE
- Ave. Duration
- 5h
- Frequency
- Once daily
- Estimated price
- $45–70
- Website
- Greyhound
Bus from Iowa City to Moline Center Station
- Ave. Duration
- 1h 25m
- Frequency
- Once daily
- Estimated price
- $10–16
- Website
- Greyhound
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Omaha to Sioux City
- Ave. Duration
- 1h 40m
- Frequency
- Once daily
- Estimated price
- $30–45
- Book at
- Jefferson Lines
- Adult
- $30–45
Bus from Sioux Falls to Sioux City
- Ave. Duration
- 1h 55m
- Frequency
- Once daily
- Estimated price
- $30–50
- Book at
- Jefferson Lines
- Adult
- $30–50
- Phone
- +1-319-362-0375
- Website
- 380 Express Corridor Rides
Bus from Court St Transportation Center to GTC Bay 9
- Ave. Duration
- 51 min
- Frequency
- Hourly
- Website
- 380 Express Corridor Rides
- Schedules at
- 380 Express Schedule
Bus from Court St Transportation Center to GTC Bay 9
- Ave. Duration
- 51 min
- Frequency
- Hourly
- Website
- 380 Express Corridor Rides
- Schedules at
- 380 Express Schedule
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Booking & Getting There
There are 35+ hotels available in Sioux City.











