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How to get fromIowa State University to Knoxvilleby shuttle, plane, bus (Flixbus), bus, train, car, or bus (Greyhound, Flixbus)

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There are 10 ways to get from Iowa State University to Knoxville by shuttle, plane, bus (Flixbus), bus, train, car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Shuttle to Des Moines, fly to Mcghee Tyson Airport

    best
    1. Take a shuttle bus from Ames, IA - Iowa State University to Des Moines International Airport, IAshuttle bus
    2. Fly from Des Moines (DSM) to Mcghee Tyson Airport (TYS)plane plane DSM - TYS
    6h 26m
    $367–1,460

  2. Drive 823.3 mi

    cheapest
    1. Drive from Iowa State University to Knoxvillecar car 823.3 mi
    14h 27m
    $151–217

  3. Bus via Farragut

    1. Take the bus from Ames to Des Moinesbus bus
    2. Take the bus from Des Moines to Chicagobus bus
    3. Take the bus from Chicago Bus Station to New York Midtownbus bus
    4. Take the bus from New York to Knoxvillebus bus Nyc
    39h 44m

  4. Bus, train via Ossining

    1. Take the bus from Ames to Des Moinesbus bus
    2. Take the bus from Des Moines to Chicagobus bus
    3. Take the train from Chicago Union Station to Croton-Harmon Amtrak Stationtrain train
    4. Take the train from Croton-Harmon to 125th Street - Harlemtrain train
    5. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    43h 34m

  5. Shuttle to Des Moines, fly to Nashville, drive

    1. Take a shuttle bus from Ames, IA - Iowa State University to Des Moines International Airport, IAshuttle bus
    2. Fly from Des Moines (DSM) to Nashville (BNA)plane plane DSM - BNA
    3. Drive from Nashville-Airport-BNA to Knoxvillecar car
    6h 16m
    $222–840

  6. Shuttle to Des Moines, fly to Asheville Regional Airport, drive

    1. Take a shuttle bus from Ames, IA - Iowa State University to Des Moines International Airport, IAshuttle bus
    2. Fly from Des Moines (DSM) to Asheville Regional Airport (AVL)plane plane DSM - AVL
    3. Drive from Asheville-Airport-AVL to Knoxvillecar car
    8h 3m
    $234–875

  7. Bus to Minneapolis–Saint Paul International Airport, fly to Mcghee Tyson Airport

    1. Take the bus from Ames to MSP Airportbus bus
    2. Fly from Minneapolis–Saint Paul International Airport (MSP) to Mcghee Tyson Airport (TYS)plane plane MSP - TYS
    7h 31m
    $282–1,049

  8. Bus, train

    1. Take the bus from Ames to Des Moinesbus bus
    2. Take the bus from Des Moines to Chicago Bus Stationbus bus
    3. Take the train from Chicago Union Station to Ny Moynihan Train Hall At Penn Stationtrain train
    4. Take the bus from New York to Knoxvillebus bus Nyc
    43h 52m
    $563–1,030

  9. Bus

    1. Take the bus from Ames to Des Moinesbus bus
    2. Take the bus from Des Moines to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to New York City Chinatownbus bus
    4. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    47h 43m
    $329–512

  10. Bus, train via Saint Paul

    1. Take the bus from Ames to St. Paulbus bus
    2. Take the train from St. Paul-Minneapolis to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Croton-Harmon Amtrak Stationtrain train
    4. Take the train from Croton-Harmon to 125th Street - Harlemtrain train
    5. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    47h 57m
    $636–1,180

Des Moines (DSM) to Mcghee Tyson Airport (TYS) flights

Calendar83Weekly Planes
Duration5h 15mAverage Duration
Ticket$230Cheapest Price
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Questions & Answers

Map of how to get from Iowa State University to Knoxville.ExpandLaunch map view
  • Distance: 708.1 mi
  • Duration: 6h 26m

What companies run services between Iowa State University, IA, USA and Knoxville, TN, USA?

You can take a vehicle from Iowa State University to Knoxville via Ames, Des Moines, Chicago Bus Station, New York Midtown, 23 St, East Broadway, New York, and Knoxville in around 39h 44m.

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