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How to get fromIowa State University to Knoxvilleby shuttle, plane, bus, train, car, or bus (Greyhound, Flixbus)

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There are 8 ways to get from Iowa State University to Knoxville by shuttle, plane, bus, train, car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Shuttle, fly to Mcghee Tyson Airport

    best
    1. Take a shuttle bus from Ames, IA - Iowa State University to Des Moines International Airport, IAshuttle bus
    2. Fly from Des Moines (DSM) to Mcghee Tyson Airport (TYS)plane plane DSM - TYS
    5h 55m
    $377–1,660

  2. Drive  823 mi

    cheapest
    1. Drive from Iowa State University to Knoxvillecar car 823 mi
    14h 28m
    $151–217

  3. Bus, train

    1. Take the bus from Ames to St. Paulbus bus
    2. Take the train from St. Paul-Minneapolis to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Ny Moynihan Train Hall At Penn Stationtrain train
    4. Take the bus from New York to Knoxvillebus bus Nyc
    47h 19m
    $961–1,533

  4. Shuttle, bus

    1. Take a shuttle bus from Ames, IA - Iowa State University to Des Moines International Airport, IAshuttle bus
    2. Take the bus from Des Moines to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to New York City Chinatownbus bus
    4. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    2d
    $410–654

  5. Shuttle, fly to Nashville, drive

    1. Take a shuttle bus from Ames, IA - Iowa State University to Des Moines International Airport, IAshuttle bus
    2. Fly from Des Moines (DSM) to Nashville (BNA)plane plane DSM - BNA
    3. Drive from Nashville-Airport-BNA to Knoxvillecar car
    6h 16m
    $212–890

  6. Shuttle, fly to Asheville Regional Airport, drive

    1. Take a shuttle bus from Ames, IA - Iowa State University to Des Moines International Airport, IAshuttle bus
    2. Fly from Des Moines (DSM) to Asheville Regional Airport (AVL)plane plane DSM - AVL
    3. Drive from Asheville-Airport-AVL to Knoxvillecar car
    8h 29m
    $224–875

  7. Bus, train via Ossining

    1. Take the bus from Ames to St. Paulbus bus
    2. Take the train from St. Paul-Minneapolis to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Croton-Harmon Amtrak Stationtrain train
    4. Take the train from Croton-Harmon to 125th Street - Harlemtrain train
    5. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    47h 57m
    $926–1,410

  8. Bus

    1. Take the bus from Ames to St. Paulbus bus
    2. Take the bus from Saint Paul Union Depot to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to New York City Chinatownbus bus
    4. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    2d 3h
    $372–535

Des Moines (DSM) to Mcghee Tyson Airport (TYS) flights

Calendar59Weekly Planes
Duration5h 7mAverage Duration
Ticket$241Cheapest Price
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Comparing Your Travel Options

Map of how to get from Iowa State University to Knoxville.ExpandLaunch map view
  • Distance: 708.1 mi
  • Duration: 5h 55m

What companies run services between Iowa State University, IA, USA and Knoxville, TN, USA?

You can take a vehicle from Iowa State University to Knoxville Station Hall of Fame via Ames, Saint Paul Union Depot, Chicago Bus Station, New York, NY, Knoxville, TN, Walmart, and Fountain City Superstop in around 2d 3h.

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