There are 4 ways to get from Iowa State University to St. Louis by bus (Greyhound), car, shuttle, plane, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Ames to Des Moinesbus Jefferson 801 / ...
- Take the bus from Des Moines to St Louis Bus Stationbus Greyhound US0153S
10h 7m$85–157Drive 362 mi
cheapest- Drive from Iowa State University to St. Louiscar 362 mi
7h 10m$67–96Shuttle to Des Moines, fly
- Take a shuttle bus from Ames, IA - Iowa State University to Des Moines International Airport, IA
- Fly from Des Moines (DSM) to Lambert–St. Louis International Airport (STL)plane DSM - STL
6h 23m$225–1,043Bus to Minneapolis–Saint Paul International Airport, fly
- Take the bus from Ames to MSP Airportbus
- Fly from Minneapolis–Saint Paul International Airport (MSP) to Lambert–St. Louis International Airport (STL)plane MSP - STL
7h 7m$440–1,032
Des Moines (DSM) to Lambert–St. Louis International Airport (STL) flights
Questions & Answers
The cheapest way to get from Iowa State University to St. Louis is to drive which costs $65 - $100 and takes 7h 10m.
The fastest way to get from Iowa State University to St. Louis is to shuttle and fly which takes 6h 23m and costs $220 - $1,100.
No, there is no direct bus from Iowa State University to St. Louis station. However, there are services departing from Ames and arriving at St Louis Bus Station via Des Moines. The journey, including transfers, takes approximately 10h 7m.
The distance between Iowa State University and St. Louis is 450 miles. The road distance is 364.1 miles.
The best way to get from Iowa State University to St. Louis without a car is to bus which takes 10h 7m and costs $80 - $160.
It takes approximately 10h 7m to get from Iowa State University to St. Louis, including transfers.
Iowa State University to St. Louis bus services, operated by Jefferson Lines, depart from Ames station.
Iowa State University to St. Louis bus services, operated by Jefferson Lines, arrive at Des Moines station.
Yes, the driving distance between Iowa State University to St. Louis is 364 miles. It takes approximately 7h 10m to drive from Iowa State University to St. Louis.
There are 528+ hotels available in St. Louis.
What companies run services between Iowa State University, IA, USA and St. Louis, MO, USA?
You can take a vehicle from Iowa State University to St Louis Bus Station via Ames and Des Moines in around 10h 7m.
- Website
- southwest.com
Flights from Des Moines to Lambert–St. Louis International Airport via Chicago Midway
- Ave. Duration
- 5h 15m
- When
- Monday, Thursday, Friday, Tuesday, Wednesday, and Sunday
- Estimated price
- $140–850
Flights from Des Moines to Lambert–St. Louis International Airport via Denver
- Ave. Duration
- 5h 30m
- When
- Sunday
- Estimated price
- $270–1,200
Flights from Minneapolis–Saint Paul International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 26m
- When
- Every day
- Estimated price
- $100–600
Flights from Minneapolis–Saint Paul International Airport to Lambert–St. Louis International Airport via Chicago Midway
- Ave. Duration
- 3h 45m
- When
- Sunday, Monday, Thursday, and Friday
- Estimated price
- $120–650
- Website
- delta.com
Flights from Des Moines to Lambert–St. Louis International Airport via Minneapolis–Saint Paul International Airport
- Ave. Duration
- 4h 45m
- When
- Every day
- Estimated price
- $160–900
Flights from Des Moines to Lambert–St. Louis International Airport via Atlanta
- Ave. Duration
- 5h 27m
- When
- Every day
- Estimated price
- $250–1,200
Flights from Minneapolis–Saint Paul International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- $100–600
- Website
- united.com
Flights from Des Moines to Lambert–St. Louis International Airport via Chicago O'Hare
- Ave. Duration
- 4h 26m
- When
- Every day
- Estimated price
- $140–850
Flights from Des Moines to Lambert–St. Louis International Airport via Denver
- Ave. Duration
- 6h 23m
- When
- Every day
- Estimated price
- $270–1,200
- Website
- aa.com
Flights from Des Moines to Lambert–St. Louis International Airport via Chicago O'Hare
- Ave. Duration
- 5h 28m
- When
- Every day
- Estimated price
- $140–850
Flights from Des Moines to Lambert–St. Louis International Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 40m
- When
- Every day
- Estimated price
- $240–1,200
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Ames to Des Moines
- Ave. Duration
- 45 min
- Frequency
- Twice daily
- Estimated price
- $19–27
- Book at
- https://www.jeffersonlines.com
- Adult
- $19–27
Bus from Ames to MSP Airport
- Ave. Duration
- 3h 45m
- Frequency
- Once daily
- Estimated price
- $55–80
- Book at
- https://www.jeffersonlines.com
- Adult
- $55–80
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Des Moines to St Louis Bus Station
- Ave. Duration
- 8h 15m
- Frequency
- Once daily
- Estimated price
- $65–130
- Website
- https://www.greyhound.com/
- Phone
- +1 320.253.2226
- Website
- executiveexpress.biz
Shuttle from Ames, IA - Iowa State University to Des Moines International Airport, IA
- Ave. Duration
- 45 min
- Frequency
- On demand
- Estimated price
- $80–190
- Website
- https://www.executiveexpress.biz
- Schedules at
- https://www.executiveexpress.biz/coverage-areas/
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide





