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How to get fromIowa to Cape Girardeauby plane, bus (Greyhound), bus, train, car, or bus (Greyhound, Amtrak, Flixbus)

Find Transport to Cape Girardeau

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There are 9 ways to get from Iowa to Cape Girardeau by plane, bus (Greyhound), bus, train, car, or bus (Greyhound, Amtrak, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Des Moines to Cape Girardeau Municipal Airport

    best
    1. Fly from Des Moines (DSM) to Cape Girardeau Municipal Airport (CGI)plane plane DSM - CGI
    5h 14m
    $252–1,001

  2. Drive  428.5 mi

    cheapest
    1. Drive from Des Moines to Cape Girardeaucar car 428.5 mi
    8h 19m
    $79–113

  3. Bus via Kansas City

    1. Take the bus from Des Moines to Kansas Citybus bus
    2. Take the bus from Kansas City Bus Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Cape Girardeaubus bus
    11h 39m
    $118–175

  4. Bus, train

    1. Take the bus from Des Moines to Kansas Citybus bus
    2. Take the train from Kansas City to St. Louistrain train
    3. Take the bus from St Louis Bus Station to Cape Girardeaubus bus
    13h 59m
    $228–350

  5. Bus to Chicago O'Hare International Airport, fly to Cape Girardeau Municipal Airport

    1. Take the bus from Davenport to Chicago Bus Stationbus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Cape Girardeau Municipal Airport (CGI)plane plane ORD - CGI
    8h 19m
    $157–492

  6. Fly Omaha to Lambert–St. Louis International Airport, bus

    1. Fly from Omaha (OMA) to Lambert–St. Louis International Airport (STL)plane plane OMA - STL
    2. Take the bus from St Louis Bus Station to Cape Girardeaubus bus
    7h 46m
    $631–944

  7. Fly Quad City International Airport to Cape Girardeau Municipal Airport

    1. Fly from Quad City International Airport (MLI) to Cape Girardeau Municipal Airport (CGI)plane plane MLI - CGI
    6h 51m
    $125–530

  8. Bus to The Eastern Iowa Airport, fly to Cape Girardeau Municipal Airport

    1. Take the bus from Court St Transportation Center to GTC Bay 9bus bus
    2. Fly from The Eastern Iowa Airport (CID) to Cape Girardeau Municipal Airport (CGI)plane plane CID - CGI
    8h 23m

  9. Bus

    1. Take the bus from Des Moines to Galesburgbus bus
    2. Take the bus from Galesburg Amtrak Station to Springfieldbus bus
    3. Take the bus from Springfield SMTD Transfer Center to St Louis Bus Stationbus bus
    4. Take the bus from St Louis Bus Station to Cape Girardeaubus bus
    14h 1m

Des Moines (DSM) to Cape Girardeau Municipal Airport (CGI) flights

Calendar22Weekly Planes
Duration5h 47mAverage Duration
Ticket$214Cheapest Price
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Comparing Your Travel Options

Map of how to get from Iowa to Cape Girardeau.ExpandLaunch map view
  • Distance: 383.3 mi
  • Duration: 5h 14m

What companies run services between Iowa, USA and Cape Girardeau, MO, USA?

United Airlines, Corporate Flight Management Inc, and two other airlines fly from Des Moines (DSM) to Cape Girardeau Municipal Airport (CGI) 3 times a day. Alternatively, you can take a bus from Des Moines to Cape Girardeau via Kansas City, Kansas City Bus Station, St Louis Bus Station, and Cape Girardeau in around 11h 39m.

Airlines
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