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How to get fromIowa to Cape Girardeauby bus (Greyhound), car, plane, taxi, or bus

Find Transport to Cape Girardeau

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There are 8 ways to get from Iowa to Cape Girardeau by bus (Greyhound), car, plane, taxi, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Des Moines to St Louis Bus Stationbus bus Greyhound US0153S
    2. Take the bus from St Louis Bus Station to Cape Girardeaubus bus Greyhound US1173
    11h 35m
    $116–199

  2. Drive 428.5 mi

    cheapest
    1. Drive from Des Moines to Cape Girardeaucar car 428.5 mi
    8h 19m
    $79–113

  3. Fly Quad City International Airport to Williamson County Regional Airport, taxi

    1. Fly from Quad City International Airport (MLI) to Williamson County Regional Airport (MWA)plane plane MLI - MWA
    2. Take the taxi from Williamson County Regional Airport (MWA) to Cape Girardeautaxi taxi
    7h 21m
    $192–502

  4. Bus via Kansas City

    1. Take the bus from Des Moines to Kansas Citybus bus
    2. Take the bus from Kansas City Bus Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Cape Girardeaubus bus
    11h 39m
    $155–221

  5. Bus via Iowa City

    1. Take the bus from Des Moines to Iowa Citybus bus
    2. Take the bus from Iowa City to Saint Louisbus bus
    3. Take the bus from St Louis Bus Station to Cape Girardeaubus bus
    13h 14m
    $155–221

  6. Bus to Chicago O'Hare International Airport, fly to Cape Girardeau Municipal Airport

    1. Take the bus from Davenport to Chicagobus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Cape Girardeau Municipal Airport (CGI)plane plane ORD - CGI
    6h 54m
    $167–308

  7. Fly Omaha to Lambert–St. Louis International Airport, bus

    1. Fly from Omaha (OMA) to Lambert–St. Louis International Airport (STL)plane plane OMA - STL
    2. Take the bus from St Louis Bus Station to Cape Girardeaubus bus
    7h 51m
    $648–965

  8. Fly Quad City International Airport to Cape Girardeau Municipal Airport

    1. Fly from Quad City International Airport (MLI) to Cape Girardeau Municipal Airport (CGI)plane plane MLI - CGI
    7h 11m
    $135–520

Quad City International Airport (MLI) to Williamson County Regional Airport (MWA) flights

Calendar40Weekly Planes
Duration5h 3mAverage Duration
Ticket$60Cheapest Price
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Questions & Answers

Map of how to get from Iowa to Cape Girardeau.ExpandLaunch map view
  • Distance: 533.3 mi
  • Duration: 11h 35m

What companies run services between Iowa, USA and Cape Girardeau, MO, USA?

You can take a vehicle from Des Moines to Cape Girardeau via Des Moines, St Louis Bus Station, and Cape Girardeau in around 11h 35m. Alternatively, United Airlines, Corporate Flight Management Inc, and American Airlines fly from Quad City International Airport (MLI) to Cape Girardeau Municipal Airport (CGI) 4 times a day.

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