Rome2Rio

How to get fromIowa to Charlestonby plane, bus, train, or car

Find Transport to Charleston

See all options

There are 5 ways to get from Iowa to Charleston by plane, bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Des Moines

    best
    1. Fly from Des Moines (DSM) to Charleston International Airport (CHS)plane plane DSM - CHS
    6h 8m
    $161–775

  2. Fly from Quad City International Airport

    cheapest
    1. Fly from Quad City International Airport (MLI) to Charleston International Airport (CHS)plane plane MLI - CHS
    8h 14m
    $99–554

  3. Bus, train

    1. Take the bus from Des Moines to Galesburgbus bus
    2. Take the train from Galesburg Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Petersburg Amtrak Stationtrain train
    4. Take the train from Petersburg Amtrak Station to Charleston Amtrak Stationtrain train
    38h 10m
    $418–960

  4. Drive  1,158.9 mi

    1. Drive from Des Moines to Charlestoncar car 1,158.9 mi
    20h 40m
    $212–306

  5. Fly from Omaha

    1. Fly from Omaha (OMA) to Charleston International Airport (CHS)plane plane OMA - CHS
    8h 27m
    $135–705

Des Moines (DSM) to Charleston International Airport (CHS) flights

Calendar102Weekly Planes
Duration5h 36mAverage Duration
Ticket$143Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Iowa to Charleston.ExpandLaunch map view
  • Distance: 977.1 mi
  • Duration: 6h 8m

What companies run services between Iowa, USA and Charleston, SC, USA?

Delta, American Airlines, and two other airlines fly from Des Moines (DSM) to Charleston International Airport (CHS) hourly.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound