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How to get fromIowa to Charlestonby plane, bus, train, or car

Find Transport to Charleston

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There are 5 ways to get from Iowa to Charleston by plane, bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Des Moines

    best
    1. Fly from Des Moines (DSM) to Charleston International Airport (CHS)plane plane DSM - CHS
    5h 59m
    $131–575

  2. Fly from Quad City International Airport

    cheapest
    1. Fly from Quad City International Airport (MLI) to Charleston International Airport (CHS)plane plane MLI - CHS
    8h 8m
    $104–554

  3. Bus, train

    1. Take the bus from Des Moines to Galesburgbus bus
    2. Take the train from Galesburg Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Petersburg Amtrak Stationtrain train
    4. Take the train from Petersburg Amtrak Station to Charleston Amtrak Stationtrain train
    38h 10m
    $858–1,355

  4. Drive  1,158.9 mi

    1. Drive from Des Moines to Charlestoncar car 1,158.9 mi
    20h 40m
    $212–306

  5. Fly from Omaha

    1. Fly from Omaha (OMA) to Charleston International Airport (CHS)plane plane OMA - CHS
    8h 32m
    $135–705

Des Moines (DSM) to Charleston International Airport (CHS) flights

Calendar90Weekly Planes
Duration5h 45mAverage Duration
Ticket$110Cheapest Price
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Comparing Your Travel Options

Map of how to get from Iowa to Charleston.ExpandLaunch map view
  • Distance: 977.1 mi
  • Duration: 5h 59m

What companies run services between Iowa, USA and Charleston, SC, USA?

Southwest Airlines, Delta, and two other airlines fly from Des Moines (DSM) to Charleston International Airport (CHS) hourly.

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