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How to get fromIowa to Charlotteby plane, bus (Greyhound, Amtrak, Flixbus), bus, train, car, or bus (Greyhound, Flixbus)

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There are 8 ways to get from Iowa to Charlotte by plane, bus (Greyhound, Amtrak, Flixbus), bus, train, car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Des Moines

    best
    1. Fly from Des Moines (DSM) to Charlotte Douglas International Airport (CLT)plane plane DSM - CLT
    3h 15m
    $181–874

  2. Fly from Quad City International Airport

    cheapest
    1. Fly from Quad City International Airport (MLI) to Charlotte Douglas International Airport (CLT)plane plane MLI - CLT
    5h 19m
    $105–605

  3. Bus

    1. Take the bus from Des Moines to St Louis Bus Stationbus bus
    2. Take the bus from St. Louis to Carbondalebus bus
    3. Take the bus from Carbondale Intermodal Station to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Downtown to Charlotte Bus Stationbus bus
    25h 49m
    $186–348

  4. Bus, train

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus
    2. Take the train from Chicago Union Station to Carytrain train
    3. Take the train from Cary to Charlotte Amtrak Stationtrain train
    36h 43m
    $424–915

  5. Drive 1,029.4 mi

    1. Drive from Des Moines to Charlottecar car 1,029.4 mi
    17h 40m
    $188–272

  6. Bus via Kansas City

    1. Take the bus from Des Moines to Kansas Citybus bus
    2. Take the bus from Kansas City Bus Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to Charlotte Bus Stationbus bus
    26h 10m
    $203–372

  7. Bus, train via Ironville

    1. Take the bus from Des Moines to Indianapolis Union Stationbus bus
    2. Take the train from Indianapolis to Ashland Amtrak Stationtrain train
    3. Take the bus from Ashland to Wythevillebus bus
    4. Take the bus from Wytheville to Charlotte Bus Stationbus bus
    26h 10m
    $185–430

  8. Bus, train via Galesburg

    1. Take the bus from Des Moines to Galesburgbus bus
    2. Take the train from Galesburg Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Raleigh Union Stationtrain train
    4. Take the train from Raleigh Union Station to Charlotte Amtrak Stationtrain train
    37h 41m
    $454–990

Iowa to Charlotte by bus

Calendar12Weekly Buses
Duration26h 10mAverage Duration
Ticket$203Cheapest Price
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Questions & Answers

Map of how to get from Iowa to Charlotte.ExpandLaunch map view
  • Distance: 827.6 mi
  • Duration: 3h 15m

What companies run services between Iowa, USA and Charlotte, NC, USA?

American Airlines, Southwest Airlines, and two other airlines fly from Des Moines (DSM) to Charlotte Douglas International Airport (CLT) every 2 hours. Alternatively, you can take a vehicle from Des Moines to Charlotte Bus Station via Des Moines, St Louis Bus Station, St. Louis, Carbondale Intermodal Station, Atlanta Bus Station, Garnett Station, Civic Center Station, and Atlanta Downtown in around 25h 49m.

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Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

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