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How to get fromIowa to Columbiaby plane, bus, train, or car

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There are 5 ways to get from Iowa to Columbia by plane, bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Des Moines

    best
    1. Fly from Des Moines (DSM) to Columbia (CAE)plane plane DSM - CAE
    5h 59m
    $360–1,623

  2. Drive 1,049.3 mi

    cheapest
    1. Drive from Des Moines to Columbiacar car 1,049.3 mi
    18h 51m
    $192–277

  3. Bus, train

    1. Take the bus from Des Moines to Chicagobus bus Btw 1202 / ...
    2. Take the train from Chicago Union Station to Columbia Stationtrain train Floridian
    36h 4m

  4. Fly from Quad City International Airport

    1. Fly from Quad City International Airport (MLI) to Columbia (CAE)plane plane MLI - CAE
    7h 45m
    $194–1,004

  5. Bus, train via Galesburg

    1. Take the bus from Des Moines to Galesburgbus bus
    2. Take the train from Galesburg Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Columbia Stationtrain train
    38h 10m

Des Moines (DSM) to Columbia (CAE) flights

Calendar86Weekly Planes
Duration6h 18mAverage Duration
Ticket$342Cheapest Price
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Questions & Answers

Map of how to get from Iowa to Columbia.ExpandLaunch map view
  • Distance: 876.1 mi
  • Duration: 5h 59m

What companies run services between Iowa, USA and Columbia, SC, USA?

Delta, American Airlines, and United Airlines fly from Des Moines (DSM) to Columbia (CAE) every 2 hours.

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