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How to get fromIowa to Columbiaby plane, bus (Greyhound, Flixbus), bus, train, or car

Find Transport to Columbia

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There are 6 ways to get from Iowa to Columbia by plane, bus (Greyhound, Flixbus), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Des Moines

    best
    1. Fly from Des Moines (DSM) to Columbia (CAE)plane plane DSM - CAE
    5h 45m
    $131–625

  2. Fly from Quad City International Airport

    cheapest
    1. Fly from Quad City International Airport (MLI) to Columbia (CAE)plane plane MLI - CAE
    7h 52m
    $79–414

  3. Bus

    1. Take the bus from Des Moines to Kansas Citybus bus
    2. Take the bus from Kansas City Bus Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to Camdenbus bus
    5. Take the bus from Camden to Columbia, SCbus bus Nyc
    29h 34m
    $233–384

  4. Bus, train

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus Greyhound US0123S / ...
    2. Take the train from Chicago Union Station to Columbia Stationtrain train Floridian
    37h 4m
    $368–845

  5. Drive  1,049.3 mi

    1. Drive from Des Moines to Columbiacar car 1,049.3 mi
    18h 51m
    $192–277

  6. Bus, train via Galesburg

    1. Take the bus from Des Moines to Galesburgbus bus
    2. Take the train from Galesburg Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Columbia Stationtrain train
    38h 15m
    $388–910

Des Moines (DSM) to Columbia (CAE) flights

Calendar110Weekly Planes
Duration6h 9mAverage Duration
Ticket$113Cheapest Price
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Comparing Your Travel Options

Map of how to get from Iowa to Columbia.ExpandLaunch map view
  • Distance: 876.1 mi
  • Duration: 5h 45m

What companies run services between Iowa, USA and Columbia, SC, USA?

Delta, American Airlines, and United Airlines fly from Des Moines (DSM) to Columbia (CAE) hourly. Alternatively, you can take a bus from Des Moines to Sumter Laurel South via Kansas City, Kansas City Bus Station, St Louis Bus Station, Atlanta Bus Station, Camden, Columbia, SC, and Broad Marley South in around 29h 34m.

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