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How to get fromIowa to Fort Myersby plane, bus, train, car, taxi, or bus (Greyhound, Flixbus)

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There are 6 ways to get from Iowa to Fort Myers by plane, bus, train, car, taxi, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Ft. Myers

    best
    1. Fly from Des Moines (DSM) to Ft. Myers (RSW)plane plane DSM - RSW
    5h 8m
    $142–678

  2. Bus, train via New Orleans

    1. Take the bus from Des Moines to Champaign Intermodal Trans Ctrbus bus
    2. Take the train from Champaign-Urbana to New Orleans Union Passenger Terminaltrain train
    3. Take the train from New Orleans Union Passenger Terminal to Gulfport Amtrak Statrain train
    4. Take the bus from Gulfport to Fort Myersbus bus
    41h 28m
    $663–1,015

  3. Bus, train

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus
    2. Take the train from Chicago Union Station to Tampatrain train
    3. Take the bus from Tampa Bus Station to Fort Myers Bus Stopbus bus
    2d 5h
    $1,043–1,739

  4. Drive  1,422.9 mi

    1. Drive from Des Moines to Fort Myerscar car 1,422.9 mi
    25h 54m
    $260–376

  5. Fly to Punta Gorda Airport, taxi

    1. Fly from Des Moines (DSM) to Punta Gorda Airport (PGD)plane plane DSM - PGD
    2. Take the taxi from Punta Gorda Airport (PGD) to Fort Myerstaxi taxi
    3h 42m
    $189–603

  6. Bus

    1. Take the bus from Des Moines to Kansas Citybus bus
    2. Take the bus from Kansas City Bus Station to Dallas Bus Stationbus bus
    3. Take the bus from Dallas Bus Station to Houston Bus Stationbus bus
    4. Take the bus from Houston - Harrisburg Blvd to Fort Myersbus bus
    44h 2m
    $353–512

Des Moines (DSM) to Ft. Myers (RSW) flights

Calendar63Weekly Planes
Duration5h 19mAverage Duration
Ticket$129Cheapest Price
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Comparing Your Travel Options

Map of how to get from Iowa to Fort Myers.ExpandLaunch map view
  • Distance: 1,259.1 mi
  • Duration: 5h 8m

What companies run services between Iowa, USA and Fort Myers, FL, USA?

Allegiant Air, Southwest Airlines, and three other airlines fly from Des Moines (DSM) to Ft. Myers (RSW) every 3 hours. Alternatively, you can take a bus from Des Moines to Fort Myers via Kansas City, Kansas City Bus Station, Dallas Bus Station, Houston Bus Station, and Houston - Harrisburg Blvd in around 44h 2m.

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