There are 8 ways to get from Iowa to Fort Myers by plane, taxi, bus (Greyhound, Flixbus), bus, train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Des Moines to Punta Gorda Airport, taxi
best- Fly from Des Moines (DSM) to Punta Gorda Airport (PGD)plane DSM - PGD
- Take the taxi from Punta Gorda Airport (PGD) to Fort Myerstaxi
3h 42m$219–813Fly Quad City International Airport to Ft. Myers
cheapest- Fly from Quad City International Airport (MLI) to Ft. Myers (RSW)plane MLI - RSW
8h 44m$115–607Bus
- Take the bus from Des Moines to Kansas Citybus
- Take the bus from Kansas City Bus Station to St Louis Bus Stationbus
- Take the bus from St Louis Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Tampa Bus Stationbus
- Take the bus from Tampa Bus Station to Fort Myers Bus Stopbus
35h 25m$262–427Bus, train
- Take the bus from Des Moines to Chicago Bus Stationbus
- Take the train from Chicago Union Station to Tampatrain
- Take the bus from Tampa Bus Station to Fort Myers Bus Stopbus
2d 5h$521–1,229Drive 1,422.9 mi
- Drive from Des Moines to Fort Myerscar 1,422.9 mi
25h 54m$260–376Fly Quad City International Airport to Punta Gorda Airport, taxi
- Fly from Quad City International Airport (MLI) to Punta Gorda Airport (PGD)plane MLI - PGD
- Take the taxi from Punta Gorda Airport (PGD) to Fort Myerstaxi
5h 31m$167–572Bus to The Eastern Iowa Airport, fly to Punta Gorda Airport, taxi
- Take the bus from Court St Transportation Center to GTC Bay 9bus
- Fly from The Eastern Iowa Airport (CID) to Punta Gorda Airport (PGD)plane CID - PGD
- Take the taxi from Punta Gorda Airport (PGD) to Fort Myerstaxi
6h 39mBus, train via New Orleans
- Take the bus from Des Moines to Champaign Intermodal Trans Ctrbus
- Take the train from Champaign-Urbana to New Orleans Union Passenger Terminaltrain
- Take the train from New Orleans Union Passenger Terminal to Gulfport Amtrak Statrain
- Take the bus from Gulfport to Fort Myersbus
41h 28m$384–755
Iowa to Fort Myers by bus
Comparing Your Travel Options
The cheapest way to get from Iowa to Fort Myers is to drive which costs $260 - $380 and takes 25h 54m.
The fastest way to get from Iowa to Fort Myers is to fly and taxi which takes 3h 42m and costs $210 - $850.
No, there is no direct bus from Iowa to Fort Myers. However, there are services departing from Des Moines and arriving at Fort Myers Bus Stop via Kansas City Bus Station, St Louis Bus Station, Atlanta Bus Station and Tampa Bus Station. The journey, including transfers, takes approximately 35h 25m.
The distance between Iowa and Fort Myers is 1246 miles. The road distance is 1431.2 miles.
The best way to get from Iowa to Fort Myers without a car is to bus which takes 35h 25m and costs $260 - $430.
It takes approximately 3h 42m to get from Iowa to Fort Myers, including transfers.
Iowa to Fort Myers bus services, operated by Jefferson Lines, depart from Des Moines station.
The best way to get from Iowa to Fort Myers is to bus which takes 35h 25m and costs $260 - $430. Alternatively, you can fly, which costs $110 - $650 and takes 8h 44m.
Iowa to Fort Myers bus services, operated by Jefferson Lines, arrive at Kansas City station.
Fort Myers is 1h ahead of Iowa. It is currently 10:45 AM in Iowa and 11:45 AM in Fort Myers.
What companies run services between Iowa, USA and Fort Myers, FL, USA?
You can take a bus from Des Moines to Fort Myers Bus Stop via Kansas City, Kansas City Bus Station, St Louis Bus Station, Atlanta Bus Station, and Tampa Bus Station in around 35h 25m. Alternatively, Delta, United Airlines, and American Airlines fly from Quad City International Airport (MLI) to Ft. Myers (RSW) every 2 hours.
- Website
- allegiantair.com
Flights from Des Moines to Punta Gorda Airport
- Ave. Duration
- 2h 56m
- When
- Sunday and Thursday
- Estimated price
- $130–700
Flights from Des Moines to Punta Gorda Airport via Nashville
- Ave. Duration
- 5h 11m
- When
- Friday
- Estimated price
- $140–700
Flights from Quad City International Airport to Punta Gorda Airport
- Ave. Duration
- 2h 43m
- When
- Friday and Monday
- Estimated price
- $95–480
Flights from The Eastern Iowa Airport to Punta Gorda Airport
- Ave. Duration
- 2h 48m
- When
- Saturday and Wednesday
- Estimated price
- $100–490
Flights from The Eastern Iowa Airport to Punta Gorda Airport via Nashville
- Ave. Duration
- 5h 51m
- When
- Friday
- Estimated price
- $100–490
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Chicago Union Station to Tampa
- Ave. Duration
- 40h 47m
- Frequency
- Once daily
- Estimated price
- $440–1,100
- Website
- Amtrak
Train from Champaign-Urbana to New Orleans Union Passenger Terminal
- Ave. Duration
- 16h 52m
- Frequency
- Once daily
- Estimated price
- $190–470
- Website
- Amtrak
Train from New Orleans Union Passenger Terminal to Gulfport Amtrak Sta
- Ave. Duration
- 59 min
- Frequency
- Twice daily
- Estimated price
- $16–40
- Website
- Amtrak
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Des Moines to Kansas City
- Ave. Duration
- 3h 30m
- Frequency
- 3 times a day
- Estimated price
- $50–75
- Book at
- Jefferson Lines
- Adult
- $50–75
- Ave. Duration
- 35 min
- Estimated price
- $70–90
Gulf Coast Car Service
- Phone
- +1 941-391-8800
- Website
- gulfcoastcarservice.com
Gulf Coast Car Service
- Phone
- +1 941-391-8800
- Website
- gulfcoastcarservice.com
Gulf Coast Car Service
- Phone
- +1 941-391-8800
- Website
- gulfcoastcarservice.com
Want to know more about travelling around United States
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Booking & Getting There
Yes, the driving distance between Iowa to Fort Myers is 1431 miles. It takes approximately 25h 54m to drive from Iowa to Fort Myers.
There are 3418+ hotels available in Fort Myers.






