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How to get fromIowa to Gainesvilleby plane, bus (Greyhound, Flixbus), bus, train, or car

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There are 9 ways to get from Iowa to Gainesville by plane, bus (Greyhound, Flixbus), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Des Moines

    best
    1. Fly from Des Moines (DSM) to Gainesville Regional Airport (GNV)plane plane DSM - GNV
    5h 54m
    $150–673

  2. Fly from Quad City International Airport

    cheapest
    1. Fly from Quad City International Airport (MLI) to Gainesville Regional Airport (GNV)plane plane MLI - GNV
    8h 57m
    $94–444

  3. Bus

    1. Take the bus from Des Moines to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Gainesvillebus bus
    27h 15m
    $194–370

  4. Bus, train

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus
    2. Take the train from Chicago Union Station to Jacksonvilletrain train
    3. Take the bus from Jacksonville to Gainesvillebus bus
    46h 35m
    $535–1,125

  5. Drive 1,198 mi

    1. Drive from Des Moines to Gainesvillecar car 1,198 mi
    21h 40m
    $219–316

  6. Fly from Omaha

    1. Fly from Omaha (OMA) to Gainesville Regional Airport (GNV)plane plane OMA - GNV
    8h 20m
    $125–605

  7. Bus to The Eastern Iowa Airport, fly

    1. Take the bus from Court St Transportation Center to GTC Bay 9bus bus
    2. Fly from The Eastern Iowa Airport (CID) to Gainesville Regional Airport (GNV)plane plane CID - GNV
    10h

  8. Bus via Kansas City

    1. Take the bus from Des Moines to Kansas Citybus bus
    2. Take the bus from Kansas City Bus Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to Gainesvillebus bus
    27h 20m
    $213–382

  9. Bus, train via Atlanta

    1. Take the bus from Des Moines to Kansas Citybus bus
    2. Take the train from Kansas City to St. Louistrain train
    3. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to Gainesvillebus bus
    29h 40m
    $258–492

Iowa to Gainesville by bus

Calendar12Weekly Buses
Duration27h 20mAverage Duration
Ticket$213Cheapest Price
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Questions & Answers

Map of how to get from Iowa to Gainesville.ExpandLaunch map view
  • Distance: 1,050.3 mi
  • Duration: 5h 54m

What companies run services between Iowa, USA and Gainesville, FL, USA?

Delta and American Airlines fly from Des Moines (DSM) to Gainesville Regional Airport (GNV) every 4 hours. Alternatively, you can take a vehicle from Des Moines to Gainesville via Des Moines, St Louis Bus Station, and Atlanta Bus Station in around 27h 15m.

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Want to know more about travelling around United States

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