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How to get fromIowa to Gainesvilleby plane, bus (Greyhound, Flixbus), bus, train, or car

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There are 9 ways to get from Iowa to Gainesville by plane, bus (Greyhound, Flixbus), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Des Moines to Gainesville Regional Airport

    best
    1. Fly from Des Moines (DSM) to Gainesville Regional Airport (GNV)plane plane DSM - GNV
    6h 34m
    $111–485

  2. Fly Quad City International Airport to Gainesville Regional Airport

    cheapest
    1. Fly from Quad City International Airport (MLI) to Gainesville Regional Airport (GNV)plane plane MLI - GNV
    8h 40m
    $89–444

  3. Bus

    1. Take the bus from Des Moines to Kansas Citybus bus
    2. Take the bus from Kansas City Bus Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to Gainesvillebus bus
    25h 50m
    $228–372

  4. Bus, train

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus
    2. Take the train from Chicago Union Station to Jacksonvilletrain train
    3. Take the bus from Jacksonville to Gainesvillebus bus
    46h 35m
    $924–1,519

  5. Drive  1,198 mi

    1. Drive from Des Moines to Gainesvillecar car 1,198 mi
    21h 39m
    $219–316

  6. Fly Des Moines to Orlando Sanford, drive

    1. Fly from Des Moines (DSM) to Orlando Sanford (SFB)plane plane DSM - SFB
    2. Drive from Orlando-Sanford-Airport-SFB to Gainesvillecar car
    5h 17m
    $134–533

  7. Fly Omaha to Gainesville Regional Airport

    1. Fly from Omaha (OMA) to Gainesville Regional Airport (GNV)plane plane OMA - GNV
    8h 50m
    $115–605

  8. Bus to The Eastern Iowa Airport, fly to Gainesville Regional Airport

    1. Take the bus from Court St Transportation Center to GTC Bay 9bus bus
    2. Fly from The Eastern Iowa Airport (CID) to Gainesville Regional Airport (GNV)plane plane CID - GNV
    9h 51m

  9. Bus, train via Atlanta

    1. Take the bus from Des Moines to Kansas Citybus bus
    2. Take the train from Kansas City to St. Louistrain train
    3. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to Gainesvillebus bus
    28h 10m
    $338–542

Iowa to Gainesville by bus

Calendar12Weekly Buses
Duration25h 50mAverage Duration
Ticket$228Cheapest Price
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Comparing Your Travel Options

Map of how to get from Iowa to Gainesville.ExpandLaunch map view
  • Distance: 1,050.3 mi
  • Duration: 6h 34m

What companies run services between Iowa, USA and Gainesville, FL, USA?

American Airlines and Delta fly from Des Moines (DSM) to Gainesville Regional Airport (GNV) every 4 hours. Alternatively, you can take a bus from Des Moines to Gainesville via Kansas City, Kansas City Bus Station, St Louis Bus Station, and Atlanta Bus Station in around 25h 50m.

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Want to know more about travelling around United States

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