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How to get fromIowa to Harrisburg, Paby plane, bus (Greyhound), bus, train, car, or bus (Greyhound, Flixbus)

Find Transport to Harrisburg, Pa

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There are 8 ways to get from Iowa to Harrisburg, Pa by plane, bus (Greyhound), bus, train, car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Des Moines to Harrisburg International Airport

    best
    1. Fly from Des Moines (DSM) to Harrisburg International Airport (MDT)plane plane DSM - MDT
    5h 34m
    $100–455

  2. Fly Quad City International Airport to Harrisburg International Airport

    cheapest
    1. Fly from Quad City International Airport (MLI) to Harrisburg International Airport (MDT)plane plane MLI - MDT
    7h 18m
    $78–404

  3. Bus (Greyhound)

    1. Take the bus from Des Moines to Indianapolis Union Stationbus bus Greyhound US0157S
    2. Take the bus from Indianapolis Union Station to Harrisburg Bus Stationbus bus Greyhound US0421
    24h 30m
    $193–300

  4. Bus, train

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus
    2. Take the train from Chicago Union Station to Pittsburgh Amtrak Stationtrain train
    3. Take the train from Pittsburgh Amtrak Station to Harrisburgtrain train
    25h 9m
    $463–730

  5. Drive  972.3 mi

    1. Drive from Des Moines to Harrisburg, Pacar car 972.3 mi
    16h 2m
    $167–240

  6. Fly Des Moines to Philadelphia International Airport, train

    1. Fly from Des Moines (DSM) to Philadelphia International Airport (PHL)plane plane DSM - PHL
    2. Take the train from 30th Street Station to Harrisburgtrain train
    6h 25m
    $176–667

  7. Bus via Chicago

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus Greyhound US0155S / ...
    2. Take the bus from Chicago Bus Station to Harrisburg Bus Stationbus bus FlixBus N2640 / ...
    25h 5m
    $193–300

  8. Bus, train via Galesburg

    1. Take the bus from Des Moines to Galesburgbus bus
    2. Take the train from Galesburg Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Pittsburgh Amtrak Stationtrain train
    4. Take the train from Pittsburgh Amtrak Station to Harrisburgtrain train
    25h 20m
    $518–830

Des Moines (DSM) to Harrisburg International Airport (MDT) flights

Calendar81Weekly Planes
Duration5h 59mAverage Duration
Ticket$84Cheapest Price
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Comparing Your Travel Options

Map of how to get from Iowa to Harrisburg, Pa.ExpandLaunch map view
  • Distance: 903.3 mi
  • Duration: 5h 34m

What companies run services between Iowa, USA and Harrisburg, Pa, PA, USA?

Delta, United Airlines, and American Airlines fly from Des Moines (DSM) to Harrisburg International Airport (MDT) every 2 hours. Alternatively, you can take a vehicle from Des Moines to Harrisburg Bus Station via Des Moines and Indianapolis Union Station in around 24h 30m.

Airlines
Train operators
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