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How to get fromIowa to Key Westby plane, bus, train, shuttle, bus (Greyhound, Flixbus), or car

Find Transport to Key West

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There are 9 ways to get from Iowa to Key West by plane, bus, train, shuttle, bus (Greyhound, Flixbus), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Des Moines

    best
    1. Fly from Des Moines (DSM) to Key West International Airport (EYW)plane plane DSM - EYW
    5h 50m
    $120–456

  2. Fly from Quad City International Airport

    cheapest
    1. Fly from Quad City International Airport (MLI) to Key West International Airport (EYW)plane plane MLI - EYW
    7h 25m
    $98–425

  3. Bus, train, shuttle

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus
    2. Take the train from Chicago Union Station to Miami Amtrak Stationtrain train
    3. Take a shuttle bus from Miami, FL - International Airport to Key West, FLshuttle bus
    2d 13h
    $1,359–2,133

  4. Bus

    1. Take the bus from Des Moines to Indianapolis Union Stationbus bus
    2. Take the bus from Indianapolis Union Station to Newark Penn Stationbus bus
    3. Take the bus from Newark Penn Station to Miami Airport Stationbus bus
    4. Take the bus from Miami Airport Station to Big Pine Keybus bus
    5. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus bus Lks
    2d 14h
    $452–689

  5. Drive  1,668.1 mi

    1. Drive from Des Moines to Key Westcar car 1,668.1 mi
    30h 46m
    $305–440

  6. Fly from Waterloo Municipal Airport

    1. Fly from Waterloo Municipal Airport (ALO) to Key West International Airport (EYW)plane plane ALO - EYW
    8h 39m
    $126–477

  7. Fly from Omaha

    1. Fly from Omaha (OMA) to Key West International Airport (EYW)plane plane OMA - EYW
    8h 6m
    $124–566

  8. Bus to The Eastern Iowa Airport, fly

    1. Take the bus from Court St Transportation Center to GTC Bay 9bus bus
    2. Fly from The Eastern Iowa Airport (CID) to Key West International Airport (EYW)plane plane CID - EYW
    8h 56m

  9. Bus, train

    1. Take the bus from Des Moines to Galesburgbus bus
    2. Take the train from Galesburg Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Miami Amtrak Stationtrain train
    4. Take the bus from Miami Airport Station to Big Pine Keybus bus
    5. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus bus Lks
    2d 15h
    $1,271–2,068

Des Moines (DSM) to Key West International Airport (EYW) flights

Calendar41Weekly Planes
Duration6h 10mAverage Duration
Ticket$91Cheapest Price
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Comparing Your Travel Options

Map of how to get from Iowa to Key West.ExpandLaunch map view
  • Distance: 1,366.1 mi
  • Duration: 5h 50m

What companies run services between Iowa, USA and Key West, FL, USA?

American Airlines, Delta, and United Airlines fly from Des Moines (DSM) to Key West International Airport (EYW) every 4 hours. Alternatively, you can take a vehicle from Des Moines to N Roosevelt & 3rd Street via Des Moines, Indianapolis Union Station, Newark Penn Station, Miami Airport Station, Big Pine Key, and Big Pine Key - CVS / MM30 in around 2d 14h.

Airlines
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