Rome2Rio

How to get fromIowa to Lancasterby plane, bus, train, bus (Flixbus), car, or bus (Greyhound)

Find Transport to Lancaster

See all options

There are 8 ways to get from Iowa to Lancaster by plane, bus, train, bus (Flixbus), car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Quad City International Airport to Lancaster

    best
    1. Fly from Quad City International Airport (MLI) to Lancaster (LNS)plane plane MLI - LNS
    7h 27m
    $100–424

  2. Bus, train

    1. Take the bus from Des Moines to Chicagobus bus
    2. Take the train from Chicago Union Station to Pittsburgh Amtrak Stationtrain train
    3. Take the train from Pittsburgh Amtrak Station to Elizabethtown Amtrak Stationtrain train
    25h 33m

  3. Bus

    1. Take the bus from Des Moines to Chicagobus bus Btw 1202 / ...
    2. Take the bus from Chicago Bus Station to Harrisburg Bus Stationbus bus FlixBus N2640 / ...
    26h 17m

  4. Drive 1,007.8 mi

    1. Drive from Des Moines to Lancastercar car 1,007.8 mi
    16h 38m
    $184–266

  5. Fly Des Moines to Philadelphia International Airport, train

    1. Fly from Des Moines (DSM) to Philadelphia International Airport (PHL)plane plane DSM - PHL
    2. Take the train from 30th Street Station to Elizabethtown Amtrak Stationtrain train
    7h 37m
    $248–1,084

  6. Bus, train via Galesburg

    1. Take the bus from Des Moines to Galesburgbus bus
    2. Take the train from Galesburg Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Pittsburgh Amtrak Stationtrain train
    4. Take the train from Pittsburgh Amtrak Station to Elizabethtown Amtrak Stationtrain train
    27h 43m

  7. Bus via Indianapolis

    1. Take the bus from Des Moines to Indianapolis Union Stationbus bus Greyhound US0157S
    2. Take the bus from Indianapolis Union Station to Harrisburg Bus Stationbus bus Greyhound US0421
    27h 53m
    $169–332

  8. Bus, train #2

    1. Take the bus from Des Moines to Chicagobus bus
    2. Take the train from Chicago Union Station to 30th Street Stationtrain train
    3. Take the train from 30th Street Station to Elizabethtown Amtrak Stationtrain train
    37h 42m

Quad City International Airport (MLI) to Lancaster (LNS) flights

Calendar35Weekly Planes
Duration7h 7mAverage Duration
Ticket$79Cheapest Price
See schedules

Questions & Answers

Map of how to get from Iowa to Lancaster.ExpandLaunch map view
  • Distance: 767.2 mi
  • Duration: 7h 27m

What companies run services between Iowa, USA and Lancaster, PA, USA?

United Airlines and American Airlines fly from Quad City International Airport (MLI) to Lancaster (LNS) 5 times a day. Alternatively, you can take a bus from Des Moines to W. Chestnut & Water St. via Chicago Bus Station, Harrisburg Bus Station, Harrisburg, Elizabethtown Amtrak Station, and AMTRAK ETown in around 26h 17m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers