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How to get fromIowa to Lancasterby plane, bus (Greyhound, Flixbus), bus, train, car, or bus (Greyhound)

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There are 8 ways to get from Iowa to Lancaster by plane, bus (Greyhound, Flixbus), bus, train, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Quad City International Airport to Lancaster

    best
    1. Fly from Quad City International Airport (MLI) to Lancaster (LNS)plane plane MLI - LNS
    6h 42m
    $95–434

  2. Bus

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus Greyhound US0123S / ...
    2. Take the bus from Chicago Bus Station to Harrisburg Bus Stationbus bus FlixBus N2640 / ...
    27h 17m
    $192–295

  3. Bus, train via Pittsburgh

    1. Take the bus from Des Moines to Galesburgbus bus
    2. Take the train from Galesburg Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Pittsburgh Amtrak Stationtrain train
    4. Take the train from Pittsburgh Amtrak Station to Elizabethtown Amtrak Stationtrain train
    27h 43m
    $533–845

  4. Drive  1,007.8 mi

    1. Drive from Des Moines to Lancastercar car 1,007.8 mi
    16h 37m
    $184–266

  5. Fly Des Moines to Philadelphia International Airport, train

    1. Fly from Des Moines (DSM) to Philadelphia International Airport (PHL)plane plane DSM - PHL
    2. Take the train from 30th Street Station to Elizabethtown Amtrak Stationtrain train
    7h 55m
    $166–652

  6. Bus to Chicago O'Hare International Airport, fly to Lancaster

    1. Take the bus from Davenport to Chicago Bus Stationbus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Lancaster (LNS)plane plane ORD - LNS
    8h 50m
    $110–397

  7. Bus via Indianapolis (Greyhound)

    1. Take the bus from Des Moines to Indianapolis Union Stationbus bus Greyhound US0157S
    2. Take the bus from Indianapolis Union Station to Harrisburg Bus Stationbus bus Greyhound US0421
    27h 42m
    $197–295

  8. Bus, train

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus
    2. Take the train from Chicago Union Station to 30th Street Stationtrain train
    3. Take the train from 30th Street Station to Elizabethtown Amtrak Stationtrain train
    38h 42m
    $658–1,075

Quad City International Airport (MLI) to Lancaster (LNS) flights

Calendar24Weekly Planes
Duration6h 11mAverage Duration
Ticket$77Cheapest Price
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Comparing Your Travel Options

Map of how to get from Iowa to Lancaster.ExpandLaunch map view
  • Distance: 767.2 mi
  • Duration: 6h 42m

What companies run services between Iowa, USA and Lancaster, PA, USA?

United Airlines and American Airlines fly from Quad City International Airport (MLI) to Lancaster (LNS) 3 times a day. Alternatively, you can take a vehicle from Des Moines to W. Chestnut & Water St. via Des Moines, Chicago Bus Station, Harrisburg Bus Station, Harrisburg, Elizabethtown Amtrak Station, and AMTRAK ETown in around 27h 17m.

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