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How to get fromIowa to Mayo Clinicby bus, shuttle, car, or plane

Find Transport to Mayo Clinic

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There are 5 ways to get from Iowa to Mayo Clinic by bus, shuttle, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, shuttle

    best
    1. Take the bus from Des Moines to Owatonnabus bus Jefferson Lines 804 / ...
    2. Take a shuttle bus from Owatonna, MN to Rochestershuttle bus S MN Conn
    6h 5m
    $57–111

  2. Drive 207.6 mi

    cheapest
    1. Drive from Des Moines to Mayo Cliniccar car 207.6 mi
    3h 28m
    $38–55

  3. Fly, bus

    1. Fly from Des Moines (DSM) to Minneapolis–Saint Paul International Airport (MSP)plane plane DSM - MSP
    2. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    4h 14m
    $135–533

  4. Bus

    1. Take the bus from Des Moines to St. Paulbus bus Jefferson Lines 806 / ...
    2. Take the bus from St. Paul to Rochesterbus bus Jefferson Lines 965
    7h 13m
    $93–129

  5. Bus via Minneapolis

    1. Take the bus from Des Moines to Minneapolisbus bus Jefferson Lines 804 / ...
    2. Take the bus from Minneapolis to Rochesterbus bus Jefferson Lines 965
    9h 8m
    $95–135

Iowa to Mayo Clinic by bus and foot

Calendar7Weekly Services
Duration7h 13mAverage Duration
Ticket$93Cheapest Price
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Questions & Answers

Map of how to get from Iowa to Mayo Clinic.ExpandLaunch map view
  • Distance: 231.6 mi
  • Duration: 6h 5m

What companies run services between Iowa, USA and Mayo Clinic, MN, USA?

You can take a bus from Des Moines to Mayo Clinic via St. Paul and Rochester in around 7h 13m.

Airlines
Bus operators

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