Rome2Rio

How to get fromIowa to Mississippiby plane, bus (Greyhound), bus, train, or car

Find Transport to Mississippi

See all options

There are 7 ways to get from Iowa to Mississippi by plane, bus (Greyhound), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Des Moines

    best
    1. Fly from Des Moines (DSM) to Memphis (MEM)plane plane DSM - MEM
    4h 51m
    $240–1,148

  2. Fly from Quad City International Airport

    cheapest
    1. Fly from Quad City International Airport (MLI) to Memphis (MEM)plane plane MLI - MEM
    6h 36m
    $134–679

  3. Bus

    1. Take the bus from Des Moines to Kansas Citybus bus
    2. Take the bus from Kansas City to Memphis Bus Stationbus bus
    3. Take the bus from Memphis Bus Station to Jacksonbus bus
    19h 30m
    $199–310

  4. Bus, train

    1. Take the bus from Des Moines to Champaign Intermodal Trans Ctrbus bus Greyhound US0157S
    2. Take the train from Champaign-Urbana to Jacksontrain train City of New Orleans
    21h 15m
    $259–520

  5. Drive 803.6 mi

    1. Drive from Des Moines to Jacksoncar car 803.6 mi
    14h 17m
    $147–212

  6. Fly from Omaha

    1. Fly from Omaha (OMA) to Memphis (MEM)plane plane OMA - MEM
    7h 1m
    $195–930

  7. Bus via St. Louis (Greyhound)

    1. Take the bus from Des Moines to St Louis Bus Stationbus bus Greyhound US0153S
    2. Take the bus from St Louis Bus Station to Jacksonbus bus Greyhound US1173
    21h 5m
    $149–280

Des Moines (DSM) to Memphis (MEM) flights

Calendar103Weekly Planes
Duration5h 28mAverage Duration
Ticket$206Cheapest Price
See schedules

Questions & Answers

Map of how to get from Iowa to Mississippi.ExpandLaunch map view
  • Distance: 504.1 mi
  • Duration: 4h 51m

What companies run services between Iowa, USA and Mississippi, USA?

Delta, American Airlines, and two other airlines fly from Des Moines (DSM) to Memphis (MEM) hourly. Alternatively, you can take a vehicle from Des Moines to Jackson via Des Moines, Kansas City, and Memphis Bus Station in around 19h 30m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers