There are 8 ways to get from Iowa to Mobile by plane, bus (Greyhound, Flixbus), bus, train, car, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Des Moines to Mobile Regional Airport
best- Fly from Des Moines (DSM) to Mobile Regional Airport (MOB)plane DSM - MOB
5h 1m$169–713Fly Quad City International Airport to Mobile Regional Airport
cheapest- Fly from Quad City International Airport (MLI) to Mobile Regional Airport (MOB)plane MLI - MOB
7h 23m$117–492Bus
- Take the bus from Des Moines to Kansas Citybus
- Take the bus from Kansas City to Texarkanabus
- Take the bus from Texarkana to Shreveport Bus Stationbus
- Take the bus from Shreveport Bus Station to Baton Rouge Bus Stationbus
- Take the bus from Baton Rouge Bus Station to Mobile Bus Stationbus
26h 44m$238–366Bus, train
- Take the bus from Des Moines to Champaign Intermodal Trans Ctrbus
- Take the train from Champaign-Urbana to New Orleans Union Passenger Terminaltrain
- Take the train from New Orleans Union Passenger Terminal to Mobile Amtrak Statrain
29h 5m$278–645Drive 955.7 mi
- Drive from Des Moines to Mobilecar 955.7 mi
18h 8m$175–252Fly Des Moines to Destin–Fort Walton Beach Airport, drive
- Fly from Des Moines (DSM) to Destin–Fort Walton Beach Airport (VPS)plane DSM - VPS
- Drive from Destin–Fort Walton Beach Airport (VPS) to Mobilecar
6h 32m$158–651Fly Omaha to Mobile Regional Airport
- Fly from Omaha (OMA) to Mobile Regional Airport (MOB)plane OMA - MOB
7h 34m$143–643Bus via Indianapolis (Greyhound)
- Take the bus from Des Moines to Indianapolis Union Stationbus
- Take the bus from Indianapolis Union Station to Montgomery Intermodal Centerbus
- Take the bus from Montgomery Intermodal Center to Mobile Bus Stationbus
28h 56m$199–325
Iowa to Mobile by bus
Comparing Your Travel Options
The cheapest way to get from Iowa to Mobile is to drive which costs $170 - $260 and takes 18h 8m.
The fastest way to get from Iowa to Mobile is to fly which takes 5h 1m and costs $160 - $750.
No, there is no direct bus from Iowa to Mobile. However, there are services departing from Des Moines and arriving at Water NB at St Louis St via Kansas City, Texarkana, Shreveport Bus Station, Baton Rouge Bus Station and Govt EB at Greyhound Bus Station. The journey, including transfers, takes approximately 26h 44m.
The distance between Iowa and Mobile is 833 miles. The road distance is 961.3 miles.
The best way to get from Iowa to Mobile without a car is to bus which takes 26h 44m and costs $230 - $370.
It takes approximately 5h 1m to get from Iowa to Mobile, including transfers.
Iowa to Mobile bus services, operated by Jefferson Lines, depart from Des Moines station.
The best way to get from Iowa to Mobile is to fly which takes 5h 1m and costs $160 - $750. Alternatively, you can bus, which costs $230 - $370 and takes 26h 44m.
Iowa to Mobile bus services, operated by Jefferson Lines, arrive at Kansas City station.
Yes, the driving distance between Iowa to Mobile is 961 miles. It takes approximately 18h 8m to drive from Iowa to Mobile.
What companies run services between Iowa, USA and Mobile, AL, USA?
Delta, United Airlines, and American Airlines fly from Des Moines (DSM) to Mobile Regional Airport (MOB) every 3 hours. Alternatively, you can take a bus from Des Moines to Water NB at St Louis St via Kansas City, Texarkana, Shreveport Bus Station, Baton Rouge Bus Station, Mobile Bus Station, and Govt EB at Greyhound Bus Station in around 26h 44m.
- Website
- delta.com
Flights from Des Moines to Mobile Regional Airport via Atlanta
- Ave. Duration
- 4h 59m
- When
- Every day
- Estimated price
- $120–650
Flights from Quad City International Airport to Mobile Regional Airport via Atlanta
- Ave. Duration
- 5h 27m
- When
- Every day
- Estimated price
- $85–450
Flights from Des Moines to Destin–Fort Walton Beach Airport via Atlanta
- Ave. Duration
- 4h 48m
- When
- Every day
- Estimated price
- $120–600
Flights from Des Moines to Destin–Fort Walton Beach Airport via Minneapolis
- Ave. Duration
- 6h 33m
- When
- Every day
- Estimated price
- $140–700
Flights from Omaha to Mobile Regional Airport via Atlanta
- Ave. Duration
- 4h 34m
- When
- Every day
- Estimated price
- $110–600
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Champaign-Urbana to New Orleans Union Passenger Terminal
- Ave. Duration
- 16h 52m
- Frequency
- Once daily
- Estimated price
- $190–470
- Website
- Amtrak
Train from New Orleans Union Passenger Terminal to Mobile Amtrak Sta
- Ave. Duration
- 2h 43m
- Frequency
- Twice daily
- Estimated price
- $30–80
- Website
- Amtrak
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Des Moines to Kansas City
- Ave. Duration
- 3h 30m
- Frequency
- 3 times a day
- Estimated price
- $50–75
- Book at
- Jefferson Lines
- Adult
- $50–75
Bus from Kansas City to Texarkana
- Ave. Duration
- 8h 55m
- Frequency
- Twice daily
- Estimated price
- $110–160
- Book at
- Jefferson Lines
- Adult
- $110–160
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide
Booking & Getting There
There are 216+ hotels available in Mobile.






