There are 7 ways to get from Iowa to Myrtle Beach by plane, bus (Greyhound, Flixbus), bus, train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Des Moines
best- Fly from Des Moines (DSM) to Myrtle Beach (MYR)plane DSM - MYR
4h 48m$130–587Fly from Quad City International Airport
cheapest- Fly from Quad City International Airport (MLI) to Myrtle Beach (MYR)plane MLI - MYR
6h 45m$83–406Bus
- Take the bus from Des Moines to Kansas Citybus
- Take the bus from Kansas City Bus Station to St Louis Bus Stationbus
- Take the bus from St Louis Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Myrtle Beach Bus Stationbus
30h 50m$223–367Bus, train
- Take the bus from Des Moines to Chicago Bus Stationbus
- Take the train from Chicago Union Station to Raleigh Union Stationtrain
- Take the bus from Raleigh Bus Station to Myrtle Beach Bus Stationbus
38h 28m$352–804Drive 1,183.6 mi
- Drive from Des Moines to Myrtle Beachcar 1,183.6 mi
21h 16m$216–312Fly from Omaha
- Fly from Omaha (OMA) to Myrtle Beach (MYR)plane OMA - MYR
7h 11m$114–567Bus, train via Galesburg
- Take the bus from Des Moines to Galesburgbus
- Take the train from Galesburg Amtrak Station to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Petersburg Amtrak Stationtrain
- Take the train from Petersburg Amtrak Station to Fayetteville Amtrak Stationtrain
- Take the bus from Fayetteville Bus Station to Myrtle Beach Bus Stationbus
38h 30m$367–860
Iowa to Myrtle Beach by bus
Comparing Your Travel Options
The cheapest way to get from Iowa to Myrtle Beach is to fly which costs $80 - $410 and takes 6h 45m.
The fastest way to get from Iowa to Myrtle Beach is to fly which takes 4h 48m and costs $130 - $600.
No, there is no direct bus from Iowa to Myrtle Beach station. However, there are services departing from Des Moines and arriving at Myrtle Beach Bus Station via Kansas City Bus Station, St Louis Bus Station and Atlanta Bus Station. The journey, including transfers, takes approximately 30h 50m.
The distance between Iowa and Myrtle Beach is 985 miles. The road distance is 1190.5 miles.
The best way to get from Iowa to Myrtle Beach without a car is to bus which takes 30h 50m and costs $220 - $370.
It takes approximately 4h 48m to get from Iowa to Myrtle Beach, including transfers.
Iowa to Myrtle Beach bus services, operated by Jefferson Lines, depart from Des Moines station.
The best way to get from Iowa to Myrtle Beach is to fly which takes 4h 48m and costs $130 - $600. Alternatively, you can bus, which costs $220 - $370 and takes 30h 50m.
Iowa to Myrtle Beach bus services, operated by Jefferson Lines, arrive at Kansas City station.
Myrtle Beach is 1h ahead of Iowa. It is currently 10:28 PM in Iowa and 11:28 PM in Myrtle Beach.
What companies run services between Iowa, USA and Myrtle Beach, SC, USA?
Southwest Airlines, American Airlines, and two other airlines fly from Des Moines (DSM) to Myrtle Beach (MYR) every 4 hours. Alternatively, you can take a bus from Des Moines to Myrtle Beach Bus Station via Kansas City, Kansas City Bus Station, St Louis Bus Station, and Atlanta Bus Station in around 30h 50m.
- Website
- aa.com
Flights from Des Moines to Myrtle Beach via Reagan Washington
- Ave. Duration
- 4h 52m
- When
- Every day
- Estimated price
- $130–650
Flights from Des Moines to Myrtle Beach via Chicago O'Hare
- Ave. Duration
- 5h 47m
- When
- Wednesday
- Estimated price
- $110–600
Flights from Des Moines to Myrtle Beach via Charlotte
- Ave. Duration
- 6h 9m
- When
- Every day
- Estimated price
- $100–550
Flights from Quad City International Airport to Myrtle Beach via Chicago O'Hare
- Ave. Duration
- 4h 25m
- When
- Wednesday
- Estimated price
- $75–400
Flights from Quad City International Airport to Myrtle Beach via Charlotte
- Ave. Duration
- 6h 5m
- When
- Every day
- Estimated price
- $70–390
Flights from Quad City International Airport to Myrtle Beach via Dallas/Ft.Worth
- Ave. Duration
- 7h 22m
- When
- Every day
- Estimated price
- $120–550
Flights from Omaha to Myrtle Beach via Charlotte
- Ave. Duration
- 6h 22m
- When
- Every day
- Estimated price
- $100–550
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Chicago Union Station to Raleigh Union Station
- Ave. Duration
- 24h 1m
- Frequency
- Once daily
- Estimated price
- $260–650
- Website
- Amtrak
Train from Galesburg Amtrak Station to Chicago Union Station
- Ave. Duration
- 2h 55m
- Frequency
- 3 times a day
- Estimated price
- $40–95
- Website
- Amtrak
Train from Chicago Union Station to Petersburg Amtrak Station
- Ave. Duration
- 21h 1m
- Frequency
- Once daily
- Estimated price
- $220–550
- Website
- Amtrak
Train from Petersburg Amtrak Station to Fayetteville Amtrak Station
- Ave. Duration
- 2h 54m
- Frequency
- Twice daily
- Estimated price
- $45–110
- Website
- Amtrak
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Des Moines to Kansas City
- Ave. Duration
- 3h 30m
- Frequency
- 3 times a day
- Estimated price
- $50–75
- Book at
- Jefferson Lines
- Adult
- $50–75
Want to know more about travelling around United States
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Booking & Getting There
Yes, the driving distance between Iowa to Myrtle Beach is 1191 miles. It takes approximately 21h 16m to drive from Iowa to Myrtle Beach.
There are 5704+ hotels available in Myrtle Beach.






