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How to get fromIowa to Niagara Fallsby plane, bus (Greyhound), bus, train, car, or bus (Greyhound, Amtrak, Flixbus)

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There are 8 ways to get from Iowa to Niagara Falls by plane, bus (Greyhound), bus, train, car, or bus (Greyhound, Amtrak, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Des Moines

    best
    1. Fly from Des Moines (DSM) to Buffalo Niagara International Airport (BUF)plane plane DSM - BUF
    6h 30m
    $161–776

  2. Bus

    cheapest
    1. Take the bus from Des Moines to Chicago Bus Stationbus bus
    2. Take the bus from Chicago to Clevelandbus bus
    3. Take the bus from Cleveland, OH to Buffalo, NYbus bus
    20h 39m
    $104–242

  3. Bus, train via Galesburg

    1. Take the bus from Des Moines to Galesburgbus bus
    2. Take the train from Galesburg Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Buffalo Depew Stationtrain train
    4. Take the train from Buffalo Depew Station to Niagara Falls Amtrak Stationtrain train
    21h 54m
    $227–625

  4. Drive  831.5 mi

    1. Drive from Des Moines to Niagara Fallscar car 831.5 mi
    14h 6m
    $152–220

  5. Fly from Quad City International Airport

    1. Fly from Quad City International Airport (MLI) to Buffalo Niagara International Airport (BUF)plane plane MLI - BUF
    8h 36m
    $105–557

  6. Fly from Omaha

    1. Fly from Omaha (OMA) to Buffalo Niagara International Airport (BUF)plane plane OMA - BUF
    9h 8m
    $156–808

  7. Bus, train

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus Greyhound US0123S / ...
    2. Take the train from Chicago Union Station to Buffalo Depew Stationtrain train Lake Shore Limited
    22h 11m
    $200–416

  8. Bus via Detroit

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus
    2. Take the bus from Chicago Union Station to Detroitbus bus
    3. Take the bus from Detroit Bus Station to Torontobus bus
    4. Take the bus from Toronto Union Station to Niagara Falls, ONbus bus
    24h 25m
    $177–342

Des Moines (DSM) to Buffalo Niagara International Airport (BUF) flights

Calendar92Weekly Planes
Duration5h 12mAverage Duration
Ticket$143Cheapest Price
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Questions & Answers

Map of how to get from Iowa to Niagara Falls.ExpandLaunch map view
  • Distance: 809.5 mi
  • Duration: 6h 30m

What companies run services between Iowa, USA and Niagara Falls, NY, USA?

Southwest Airlines, Delta, and two other airlines fly from Des Moines (DSM) to Buffalo Niagara International Airport (BUF) hourly. Alternatively, you can take a vehicle from Des Moines to Main Street & Pine Avenue via Des Moines, Chicago, Cleveland, OH, and Ellicott Street & MTC Static in around 20h 39m.

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