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How to get fromIowa to North Carolinaby plane, bus, train, car, or bus (Greyhound, Flixbus)

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There are 6 ways to get from Iowa to North Carolina by plane, bus, train, car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Des Moines

    best
    1. Fly from Des Moines (DSM) to Charlotte Douglas International Airport (CLT)plane plane DSM - CLT
    3h 15m
    $161–774

  2. Fly from Quad City International Airport

    cheapest
    1. Fly from Quad City International Airport (MLI) to Charlotte Douglas International Airport (CLT)plane plane MLI - CLT
    5h 17m
    $105–555

  3. Bus, train via Ironville

    1. Take the bus from Des Moines to Indianapolis Union Stationbus bus
    2. Take the train from Indianapolis to Ashland Amtrak Stationtrain train
    3. Take the bus from Ashland to Charlotte Bus Stationbus bus
    25h 30m
    $189–390

  4. Bus, train

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus
    2. Take the train from Chicago Union Station to Carytrain train
    3. Take the train from Cary to Charlotte Amtrak Stationtrain train
    37h 10m
    $377–853

  5. Drive  1,029.4 mi

    1. Drive from Des Moines to Charlottecar car 1,029.4 mi
    17h 40m
    $188–272

  6. Bus

    1. Take the bus from Des Moines to Kansas Citybus bus
    2. Take the bus from Kansas City Bus Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to Charlotte Bus Stationbus bus
    26h 10m
    $193–357

Iowa to North Carolina by bus

Calendar12Weekly Buses
Duration26h 10mAverage Duration
Ticket$193Cheapest Price
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Questions & Answers

Map of how to get from Iowa to North Carolina.ExpandLaunch map view
  • Distance: 827.6 mi
  • Duration: 3h 15m

What companies run services between Iowa, USA and North Carolina, USA?

American Airlines, Southwest Airlines, and two other airlines fly from Des Moines (DSM) to Charlotte Douglas International Airport (CLT) every 2 hours. Alternatively, you can take a bus from Des Moines to Charlotte Bus Station via Kansas City, Kansas City Bus Station, St Louis Bus Station, and Atlanta Bus Station in around 26h 10m.

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Want to know more about travelling around United States

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