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How to get fromIowa to Panama City Beachby plane, bus (Greyhound), bus, train, car, or bus (Greyhound, Flixbus)

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There are 9 ways to get from Iowa to Panama City Beach by plane, bus (Greyhound), bus, train, car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Des Moines to Northwest Florida Beaches International Airport

    best
    1. Fly from Des Moines (DSM) to Northwest Florida Beaches International Airport (ECP)plane plane DSM - ECP
    4h 44m
    $199–788

  2. Fly Quad City International Airport to Northwest Florida Beaches International Airport

    cheapest
    1. Fly from Quad City International Airport (MLI) to Northwest Florida Beaches International Airport (ECP)plane plane MLI - ECP
    7h 5m
    $132–497

  3. Bus via Wake Village

    1. Take the bus from Des Moines to Kansas Citybus bus
    2. Take the bus from Kansas City to Texarkanabus bus
    3. Take the bus from Texarkana to Shreveport Bus Stationbus bus
    4. Take the bus from Shreveport Bus Station to Baton Rouge Bus Stationbus bus
    5. Take the bus from Baton Rouge Bus Station to Panama City Beach Bus Stationbus bus
    29h 59m
    $279–418

  4. Bus, train via New Orleans

    1. Take the bus from Des Moines to Champaign Intermodal Trans Ctrbus bus
    2. Take the train from Champaign-Urbana to New Orleans Union Passenger Terminaltrain train
    3. Take the bus from New Orleans Bus Station to Mobile Bus Stationbus bus
    4. Take the bus from Mobile Bus Station to Panama City Beach Bus Stationbus bus
    33h 16m
    $558–892

  5. Drive  1,061.1 mi

    1. Drive from Des Moines to Panama City Beachcar car 1,061.1 mi
    19h 57m
    $194–280

  6. Fly Des Moines to Destin–Fort Walton Beach Airport, drive

    1. Fly from Des Moines (DSM) to Destin–Fort Walton Beach Airport (VPS)plane plane DSM - VPS
    2. Drive from Destin–Fort Walton Beach Airport (VPS) to Panama City Beachcar car
    3h 49m
    $149–689

  7. Fly Omaha to Northwest Florida Beaches International Airport

    1. Fly from Omaha (OMA) to Northwest Florida Beaches International Airport (ECP)plane plane OMA - ECP
    7h 57m
    $153–618

  8. Bus

    1. Take the bus from Des Moines to Indianapolis Union Stationbus bus
    2. Take the bus from Indianapolis Union Station to Bloomington, INbus bus
    3. Take the bus from Bloomington to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to Tallahasseebus bus
    5. Take the bus from Tallahassee to Panama City Beach Bus Stationbus bus
    32h 49m
    $243–418

  9. Bus, train

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus
    2. Take the train from Chicago Union Station to Jacksonvilletrain train
    3. Take the bus from Jacksonville to Panama City Beach Bus Stationbus bus
    2d 4h
    $958–1,580

Des Moines (DSM) to Northwest Florida Beaches International Airport (ECP) flights

Calendar77Weekly Planes
Duration5h 10mAverage Duration
Ticket$133Cheapest Price
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Comparing Your Travel Options

Map of how to get from Iowa to Panama City Beach.ExpandLaunch map view
  • Distance: 912.9 mi
  • Duration: 4h 44m

What companies run services between Iowa, USA and Panama City Beach, FL, USA?

Delta, Southwest Airlines, and two other airlines fly from Des Moines (DSM) to Northwest Florida Beaches International Airport (ECP) every 2 hours. Alternatively, you can take a bus from Des Moines to Panama City Beach via Kansas City, Texarkana, Shreveport Bus Station, Baton Rouge Bus Station, and Panama City Beach Bus Station in around 29h 59m.

Airlines
Train operators
Bus operators

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Need to know: Greyhound

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