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How to get fromIowa to Panama City Beachby plane, bus (Greyhound), bus, train, car, or bus (Amtrak, Flixbus, Greyhound)

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There are 10 ways to get from Iowa to Panama City Beach by plane, bus (Greyhound), bus, train, car, or bus (Amtrak, Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Des Moines to Northwest Florida Beaches International Airport

    best
    1. Fly from Des Moines (DSM) to Northwest Florida Beaches International Airport (ECP)plane plane DSM - ECP
    4h 29m
    $208–786

  2. Fly Quad City International Airport to Northwest Florida Beaches International Airport

    cheapest
    1. Fly from Quad City International Airport (MLI) to Northwest Florida Beaches International Airport (ECP)plane plane MLI - ECP
    6h 58m
    $137–487

  3. Bus

    1. Take the bus from Des Moines to Indianapolisbus bus
    2. Take the bus from Indianapolis Union Station to Montgomery Intermodal Centerbus bus
    3. Take the bus from Montgomery Intermodal Center to Tallahasseebus bus
    4. Take the bus from Tallahassee to Panama City Beach Bus Stationbus bus
    31h 54m

  4. Bus, train via New Orleans

    1. Take the bus from Des Moines to Champaignbus bus
    2. Take the train from Champaign-Urbana to New Orleans Union Passenger Terminaltrain train
    3. Take the bus from New Orleans Bus Station to Mobile Bus Stationbus bus
    4. Take the bus from Mobile Bus Station to Panama City Beach Bus Stationbus bus
    33h 16m

  5. Drive 1,061.1 mi

    1. Drive from Des Moines to Panama City Beachcar car 1,061.1 mi
    19h 57m
    $194–280

  6. Fly Des Moines to Destin–Fort Walton Beach Airport, drive

    1. Fly from Des Moines (DSM) to Destin–Fort Walton Beach Airport (VPS)plane plane DSM - VPS
    2. Drive from Destin–Fort Walton Beach Airport (VPS) to Panama City Beachcar car
    5h 44m
    $168–737

  7. Fly The Eastern Iowa Airport to Northwest Florida Beaches International Airport

    1. Fly from The Eastern Iowa Airport (CID) to Northwest Florida Beaches International Airport (ECP)plane plane CID - ECP
    6h 51m
    $235–922

  8. Fly Omaha to Northwest Florida Beaches International Airport

    1. Fly from Omaha (OMA) to Northwest Florida Beaches International Airport (ECP)plane plane OMA - ECP
    7h 2m
    $163–618

  9. Bus via Springfield

    1. Take the bus from Des Moines to Galesburgbus bus
    2. Take the bus from Galesburg Amtrak Station to Springfieldbus bus
    3. Take the bus from Springfield SMTD Transfer Center to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to Tallahasseebus bus
    5. Take the bus from Tallahassee to Panama City Beach Bus Stationbus bus
    32h 5m

  10. Bus, train

    1. Take the bus from Des Moines to Chicagobus bus
    2. Take the train from Chicago Union Station to Jacksonvilletrain train
    3. Take the bus from Jacksonville to Panama City Beach Bus Stationbus bus
    2d 3h

Des Moines (DSM) to Northwest Florida Beaches International Airport (ECP) flights

Calendar55Weekly Planes
Duration6h 3mAverage Duration
Ticket$149Cheapest Price
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Questions & Answers

Map of how to get from Iowa to Panama City Beach.ExpandLaunch map view
  • Distance: 912.9 mi
  • Duration: 4h 29m

What companies run services between Iowa, USA and Panama City Beach, FL, USA?

Southwest Airlines, Delta, and two other airlines fly from Des Moines (DSM) to Northwest Florida Beaches International Airport (ECP) every 4 hours. Alternatively, you can take a bus from Des Moines to Panama City Beach via Indianapolis Union Station, Montgomery Intermodal Center, Tallahassee, and Panama City Beach Bus Station in around 31h 54m.

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