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How to get fromIowa to Port Saint Lucieby plane, car, bus (Greyhound, Flixbus), bus, train, or taxi

Find Transport to Port Saint Lucie

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There are 8 ways to get from Iowa to Port Saint Lucie by plane, car, bus (Greyhound, Flixbus), bus, train, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Des Moines to Orlando Sanford, drive

    best
    1. Fly from Des Moines (DSM) to Orlando Sanford (SFB)plane plane DSM - SFB
    2. Drive from Orlando-Sanford-Airport-SFB to Port Saint Luciecar car
    5h 22m
    $138–538

  2. Bus

    1. Take the bus from Des Moines to Kansas Citybus bus
    2. Take the bus from Kansas City Bus Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to Port St Luciebus bus
    32h 59m
    $268–432

  3. Bus, train

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus
    2. Take the train from Chicago Union Station to Kissimmee Amtrak Stationtrain train
    3. Take the bus from Kissimmee -1471 East Osceola Parkway to Fort Piercebus bus
    2d 2h
    $1,045–1,642

  4. Drive  1,421.2 mi

    1. Drive from Des Moines to Port Saint Luciecar car 1,421.2 mi
    25h 8m
    $260–375

  5. Fly Quad City International Airport to Melbourne International Airport, taxi, bus

    1. Fly from Quad City International Airport (MLI) to Melbourne International Airport (MLB)plane plane MLI - MLB
    2. Take the taxi from Melbourne International Airport (MLB) to Sebastiantaxi taxi
    3. Take the bus from Sebastian to Port St Luciebus bus
    11h 18m
    $189–594

  6. Fly Omaha to Fort Lauderdale–Hollywood International Airport, bus

    1. Fly from Omaha (OMA) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane OMA - FLL
    2. Take the bus from Fort Lauderdale - Broward Blvd Park and Ride to Fort Piercebus bus
    9h 37m
    $173–748

  7. Fly Omaha to Orlando, bus

    1. Fly from Omaha (OMA) to Orlando (MCO)plane plane OMA - MCO
    2. Take the bus from Kissimmee -1471 East Osceola Parkway to Fort Piercebus bus
    10h 10m
    $157–647

  8. Bus to The Eastern Iowa Airport, fly to Orlando Sanford, drive

    1. Take the bus from Court St Transportation Center to GTC Bay 9bus bus
    2. Fly from The Eastern Iowa Airport (CID) to Orlando Sanford (SFB)plane plane CID - SFB
    3. Drive from Orlando-Sanford-Airport-SFB to Port Saint Luciecar car
    8h 20m

Iowa to Port Saint Lucie by bus

Calendar7Weekly Buses
Duration32h 59mAverage Duration
Ticket$268Cheapest Price
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Comparing Your Travel Options

Map of how to get from Iowa to Port Saint Lucie.ExpandLaunch map view
  • Distance: 1,262.1 mi
  • Duration: 5h 22m

What companies run services between Iowa, USA and Port Saint Lucie, FL, USA?

You can take a bus from Des Moines to SW PSL Blvd & SE Bayshore Blvd via Kansas City, Kansas City Bus Station, St Louis Bus Station, Atlanta Bus Station, and SW Gatlin Blvd & SW Brescia St in around 32h 59m.

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