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How to get fromIowa to Port Saint Lucieby plane, car, bus (Greyhound, Flixbus), bus, or train

Find Transport to Port Saint Lucie

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There are 4 ways to get from Iowa to Port Saint Lucie by plane, car, bus (Greyhound, Flixbus), bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly, drive

    best
    1. Fly from Des Moines (DSM) to Orlando Sanford (SFB)plane plane DSM - SFB
    2. Drive from Orlando-Sanford-Airport-SFB to Port Saint Luciecar car
    5h 21m
    $173–708
  2. Bus

    1. Take the bus from Des Moines to Kansas Citybus bus
    2. Take the bus from Kansas City Bus Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to Port St Luciebus bus
    34h 29m
    $253–407
  3. Bus, train

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus
    2. Take the train from Chicago Union Station to Kissimmee Amtrak Stationtrain train
    3. Take the bus from Kissimmee -1471 East Osceola Parkway to Fort Piercebus bus
    2d 2h
    $510–1,137
  4. Drive  1,421.2 mi

    1. Drive from Des Moines to Port Saint Luciecar car 1,421.2 mi
    25h 8m
    $260–375

Iowa to Port Saint Lucie by bus

Calendar7Weekly Buses
Duration34h 29mAverage Duration
Ticket$253Cheapest Price
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Comparing Your Travel Options

What companies run services between Iowa, USA and Port Saint Lucie, FL, USA?

You can take a bus from Des Moines to SW PSL Blvd & SE Bayshore Blvd via Kansas City, Kansas City Bus Station, St Louis Bus Station, Atlanta Bus Station, and SW Gatlin Blvd & SW Brescia St in around 34h 29m.

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