Rome2Rio

How to get fromIowa to Port Saint Lucieby plane, car, bus (Flixbus), bus, train, or bus (Greyhound)

Find Transport to Port Saint Lucie

See all options

There are 8 ways to get from Iowa to Port Saint Lucie by plane, car, bus (Flixbus), bus, train, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Des Moines to Orlando Sanford, drive

    best
    1. Fly from Des Moines (DSM) to Orlando Sanford (SFB)plane plane DSM - SFB
    2. Drive from Orlando-Sanford-Airport-SFB to Port Saint Luciecar car
    5h 31m
    $202–806

  2. Fly Omaha to Orlando, bus

    cheapest
    1. Fly from Omaha (OMA) to Orlando (MCO)plane plane OMA - MCO
    2. Take the bus from Orlando RedCoach Station to Fort Piercebus bus
    9h
    $153–610

  3. Bus via Champaign

    1. Take the bus from Des Moines to Champaignbus bus
    2. Take the bus from Champaign Intermodal Trans Ctr to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Port St Luciebus bus
    35h 49m
    $333–494

  4. Bus, train

    1. Take the bus from Des Moines to Chicagobus bus
    2. Take the train from Chicago Union Station to Kissimmee Amtrak Stationtrain train
    3. Take the bus from Kissimmee to Fort Piercebus bus
    2d 2h
    $668–1,360

  5. Drive 1,421.2 mi

    1. Drive from Des Moines to Port Saint Luciecar car 1,421.2 mi
    25h 8m
    $260–375

  6. Bus to The Eastern Iowa Airport, fly to Orlando Sanford, drive

    1. Take the bus from Court St Transportation Center to GTC Bay 9bus bus
    2. Fly from The Eastern Iowa Airport (CID) to Orlando Sanford (SFB)plane plane CID - SFB
    3. Drive from Orlando-Sanford-Airport-SFB to Port Saint Luciecar car
    8h 27m

  7. Fly Omaha to Miami International Airport, train, bus

    1. Fly from Omaha (OMA) to Miami International Airport (MIA)plane plane OMA - MIA
    2. Take the train from Miami Airport Station to Fort Lauderdale Stationtrain train
    3. Take the bus from Fort Lauderdale - Broward Blvd Park and Ride to Fort Piercebus bus
    10h 16m
    $176–699

  8. Bus

    1. Take the bus from Des Moines to Indianapolis Union Stationbus bus
    2. Take the bus from Indianapolis Union Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Fort Piercebus bus
    39h 24m
    $334–522

Iowa to Port Saint Lucie by bus

Calendar7Weekly Buses
Duration35h 49mAverage Duration
Ticket$333Cheapest Price
See schedules

Questions & Answers

Map of how to get from Iowa to Port Saint Lucie.ExpandLaunch map view
  • Distance: 1,262.1 mi
  • Duration: 5h 31m

What companies run services between Iowa, USA and Port Saint Lucie, FL, USA?

You can take a bus from Des Moines to SW PSL Blvd & SE Bayshore Blvd via Champaign, Champaign Intermodal Trans Ctr, Atlanta Bus Station, and SW Gatlin Blvd & SW Brescia St in around 35h 49m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers