There are 5 ways to get from Iowa to Saint Charles by bus, plane, bus (Greyhound), train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Line 41 bus to Omaha, fly, line 34 bus
best- Take the bus from 1st Ave & 8th St NE to 11th & Dodge NEbus
- Fly from Omaha (OMA) to Lambert–St. Louis International Airport (STL)plane OMA - STL
- Take the bus from North Hanley Transit Center to 4375 Rider Trail North Sbbus
5h 2m$607–907Drive 310.1 mi
cheapest- Drive from Des Moines to Saint Charlescar 310.1 mi
6h 19m$57–82Bus
- Take the bus from Des Moines to Kansas Citybus Jefferson Lines 803 / ...
- Take the bus from Kansas City Bus Station to St Louis Bus Stationbus Greyhound US0180s / ...
9h 55m$92–141Bus, train
- Take the bus from Des Moines to Kansas Citybus Jefferson Lines 803 / ...
- Take the train from Kansas City to St. Louistrain Missouri River Runner / ...
12h 15m$122–246Fly from Quad City International Airport
- Fly from Quad City International Airport (MLI) to Lambert–St. Louis International Airport (STL)plane MLI - STL
7h 9m$76–466
Iowa to Saint Charles by bus and train
Comparing Your Travel Options
The cheapest way to get from Iowa to Saint Charles is to drive which costs $55 - $85 and takes 6h 19m.
The fastest way to get from Iowa to Saint Charles is to line 41 bus and fly and line 34 bus which takes 5h 2m and costs $600 - $950.
No, there is no direct bus from Iowa to Saint Charles. However, there are services departing from Des Moines and arriving at 4375 Rider Trail North Sb via Kansas City Bus Station and North Hanley Transit Center. The journey, including transfers, takes approximately 9h 55m.
The distance between Iowa and Saint Charles is 368 miles. The road distance is 311.9 miles.
The best way to get from Iowa to Saint Charles without a car is to bus which takes 9h 55m and costs $90 - $150.
It takes approximately 5h 2m to get from Iowa to Saint Charles, including transfers.
Iowa to Saint Charles bus services, operated by Jefferson Lines, depart from Des Moines station.
The best way to get from Iowa to Saint Charles is to bus which takes 9h 55m and costs $90 - $150. Alternatively, you can fly, which costs $75 - $470 and takes 7h 9m.
Iowa to Saint Charles bus services, operated by Jefferson Lines, arrive at Kansas City station.
Yes, the driving distance between Iowa to Saint Charles is 312 miles. It takes approximately 6h 19m to drive from Iowa to Saint Charles.
What companies run services between Iowa, USA and Saint Charles, MO, USA?
You can take a bus from Des Moines to 4375 Rider Trail North Sb via Kansas City, Kansas City Bus Station, St Louis Bus Station, CIVIC CENTER station, NORTH HANLEY station, and North Hanley Transit Center in around 9h 55m. Alternatively, United Airlines, American Airlines, and Delta fly from Quad City International Airport (MLI) to Lambert–St. Louis International Airport (STL) hourly.
- Website
- aa.com
Flights from Quad City International Airport to Lambert–St. Louis International Airport via Chicago O'Hare
- Ave. Duration
- 5h 25m
- When
- Every day
- Estimated price
- $70–460
Flights from Quad City International Airport to Lambert–St. Louis International Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 25m
- When
- Every day
- Estimated price
- $140–700
Flights from Quad City International Airport to Lambert–St. Louis International Airport via Charlotte
- Ave. Duration
- 7h 42m
- When
- Every day
- Estimated price
- $140–700
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Kansas City to St. Louis
- Ave. Duration
- 5h 40m
- Frequency
- Twice daily
- Estimated price
- $65–170
- Website
- Amtrak
- Phone
- (402) 341-0800
- [email protected]
- Website
- Omaha Metro
Bus from 1st Ave & 8th St NE to 11th & Dodge NE
- Ave. Duration
- 22 min
- Frequency
- Hourly
- Estimated price
- $1–2
- Schedules at
- Omaha Metro
Want to know more about travelling around United States
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Booking & Getting There
There are 234+ hotels available in Saint Charles.




