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How to get fromIowa to Saint Charlesby bus, plane, bus (Greyhound), or car

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There are 4 ways to get from Iowa to Saint Charles by bus, plane, bus (Greyhound), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Line 41 bus to Omaha, fly, line 34 bus

    best
    1. Take the bus from 1st Ave & 8th St NE to 11th & Dodge NEbus bus
    2. Fly from Omaha (OMA) to Lambert–St. Louis International Airport (STL)plane plane OMA - STL
    3. Take the bus from North Hanley Transit Center to 4375 Rider Trail North Sbbus bus
    5h 7m
    $607–907
  2. Drive 310.1 mi

    cheapest
    1. Drive from Des Moines to Saint Charlescar car 310.1 mi
    6h 19m
    $57–82
  3. Bus (Greyhound)

    1. Take the bus from Des Moines to St Louis Bus Stationbus bus Greyhound US0153S
    9h 46m
    $78–134
  4. Fly from Quad City International Airport

    1. Fly from Quad City International Airport (MLI) to Lambert–St. Louis International Airport (STL)plane plane MLI - STL
    6h 57m
    $86–486

Omaha (OMA) to Lambert–St. Louis International Airport (STL) flights

Calendar14Weekly Planes
Duration1h 15mAverage Duration
Ticket$97Cheapest Price
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Questions & Answers

What companies run services between Iowa, USA and Saint Charles, MO, USA?

Greyhound USA operates a bus from Des Moines to St Louis Bus Station once daily. Tickets cost $65–120 and the journey takes 8h 15m. Alternatively, United Airlines, American Airlines, and Delta fly from Quad City International Airport (MLI) to Lambert–St. Louis International Airport (STL) hourly.

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Bus operators

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