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How to get fromIowa to San Diegoby plane, bus, train, or car

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There are 5 ways to get from Iowa to San Diego by plane, bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Des Moines

    best
    1. Fly from Des Moines (DSM) to San Diego International Airport (SAN)plane plane DSM - SAN
    5h 21m
    $238–971

  2. Fly from Omaha

    cheapest
    1. Fly from Omaha (OMA) to San Diego International Airport (SAN)plane plane OMA - SAN
    5h 54m
    $153–703

  3. Bus

    1. Take the bus from Des Moines to Denverbus bus
    2. Take the bus from Denver Union Station to Las Vegas BusTerminalbus bus
    3. Take the bus from Las Vegas to Escondidobus bus
    4. Take the bus from Escondido Transit Center to Broadway & Union Stbus bus 235 / ...
    38h 54m
    $393–568

  4. Bus, train

    1. Take the bus from Des Moines to Kansas Citybus bus
    2. Take the train from Kansas City to Fullerton Amtrak Stationtrain train
    3. Take the train from Fullerton Amtrak Station to San Diegotrain train
    43h 23m
    $633–1,342

  5. Drive 1,745.2 mi

    1. Drive from Des Moines to San Diegocar car 1,745.2 mi
    27h 5m
    $319–461

Iowa to San Diego by bus and foot

Calendar7Weekly Services
Duration38h 54mAverage Duration
Ticket$393Cheapest Price
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Questions & Answers

Map of how to get from Iowa to San Diego.ExpandLaunch map view
  • Distance: 1,433.1 mi
  • Duration: 5h 21m

What companies run services between Iowa, USA and San Diego, CA, USA?

Southwest Airlines, United Airlines, and two other airlines fly from Des Moines (DSM) to San Diego International Airport (SAN) every 2 hours. Alternatively, you can take a bus from Des Moines to Broadway & Union St via Denver, Denver Union Station, Las Vegas BusTerminal, South Strip Transit Terminal, NB Casino Center at Coolidge, Las Vegas, Escondido, and Escondido Transit Center in around 38h 54m.

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