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How to get fromIowa to Syracuseby plane, bus, train, bus (Greyhound), or car

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There are 8 ways to get from Iowa to Syracuse by plane, bus, train, bus (Greyhound), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Des Moines

    best
    1. Fly from Des Moines (DSM) to Syracuse Hancock International Airport (SYR)plane plane DSM - SYR
    6h 20m
    $259–1,229

  2. Fly from Quad City International Airport

    cheapest
    1. Fly from Quad City International Airport (MLI) to Syracuse Hancock International Airport (SYR)plane plane MLI - SYR
    8h 17m
    $143–760

  3. Bus, train

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus Greyhound US0123S / ...
    2. Take the train from Chicago Union Station to Syracuse Regional Transportation Centertrain train Lake Shore Limited
    21h 17m
    $269–545

  4. Bus (Greyhound)

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus
    2. Take the bus from Chicago Bus Station to Cleveland Bus Stationbus bus
    3. Take the bus from Cleveland Bus Station to Syracuse Bus Stationbus bus
    23h 10m
    $159–315

  5. Drive 992 mi

    1. Drive from Des Moines to Syracusecar car 992 mi
    16h 46m
    $181–262

  6. Fly from Waterloo Municipal Airport

    1. Fly from Waterloo Municipal Airport (ALO) to Syracuse Hancock International Airport (SYR)plane plane ALO - SYR
    6h 56m
    $171–832

  7. Fly from Omaha

    1. Fly from Omaha (OMA) to Syracuse Hancock International Airport (SYR)plane plane OMA - SYR
    9h 11m
    $214–1,011

  8. Bus, train via Galesburg

    1. Take the bus from Des Moines to Galesburgbus bus
    2. Take the train from Galesburg Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Syracuse Regional Transportation Centertrain train
    22h 28m
    $299–620

Des Moines (DSM) to Syracuse Hancock International Airport (SYR) flights

Calendar80Weekly Planes
Duration6h 5mAverage Duration
Ticket$248Cheapest Price
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Questions & Answers

Map of how to get from Iowa to Syracuse.ExpandLaunch map view
  • Distance: 919.3 mi
  • Duration: 6h 20m

What companies run services between Iowa, USA and Syracuse, NY, USA?

Allegiant Air, Delta, and two other airlines fly from Des Moines (DSM) to Syracuse Hancock International Airport (SYR) every 2 hours. Alternatively, you can take a vehicle from Des Moines to Syracuse Bus Station via Des Moines, Chicago Bus Station, and Cleveland Bus Station in around 23h 10m.

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