There are 6 ways to get from Iowa to Tupelo by plane, bus, bus (Greyhound, Flixbus), car, bus (Greyhound, Amtrak, Flixbus), or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Des Moines, bus
best- Fly from Des Moines (DSM) to Nashville (BNA)plane DSM - BNA
- Take the bus from Nashville Bus Station to Memphis Bus Stationbus
- Take the bus from Memphis Bus Station to Tupelobus
9h 33m$167–669Drive 681.7 mi
cheapest- Drive from Des Moines to Tupelocar 681.7 mi
12h 45m$125–180Bus via Kansas City
- Take the bus from Des Moines to Kansas Citybus
- Take the bus from Kansas City Bus Station to St Louis Bus Stationbus
- Take the bus from St Louis Bus Station to Memphis Bus Stationbus
- Take the bus from Memphis Bus Station to Tupelobus
17h 49m$154–251Fly from Omaha, bus
- Fly from Omaha (OMA) to Nashville (BNA)plane OMA - BNA
- Take the bus from Nashville Bus Station to Memphis Bus Stationbus
- Take the bus from Memphis Bus Station to Tupelobus
12h 17m$501–1,049Bus
- Take the bus from Des Moines to Galesburgbus
- Take the bus from Galesburg Amtrak Station to Springfieldbus
- Take the bus from Springfield SMTD Transfer Center to Memphis Bus Stationbus
- Take the bus from Memphis Bus Station to Tupelobus
18h 51m$148–236Bus, train
- Take the bus from Des Moines to Kansas Citybus
- Take the train from Kansas City to St. Louistrain
- Take the bus from St Louis Bus Station to Memphis Bus Stationbus
- Take the bus from Memphis Bus Station to Tupelobus
20h 9m$184–346
Des Moines (DSM) to Nashville (BNA) flights
Comparing Your Travel Options
The cheapest way to get from Iowa to Tupelo is to drive which costs $120 - $180 and takes 12h 45m.
The fastest way to get from Iowa to Tupelo is to fly and bus which takes 9h 33m and costs $160 - $700.
No, there is no direct bus from Iowa to Tupelo. However, there are services departing from Des Moines and arriving at Tupelo via Kansas City Bus Station, St Louis Bus Station and Memphis Bus Station. The journey, including transfers, takes approximately 17h 49m.
The distance between Iowa and Tupelo is 863 miles. The road distance is 685.6 miles.
The best way to get from Iowa to Tupelo without a car is to bus via Kansas City which takes 17h 49m and costs $150 - $260.
It takes approximately 9h 33m to get from Iowa to Tupelo, including transfers.
Iowa to Tupelo bus services, operated by Jefferson Lines, depart from Des Moines station.
Iowa to Tupelo bus services, operated by Jefferson Lines, arrive at Kansas City station.
Yes, the driving distance between Iowa to Tupelo is 686 miles. It takes approximately 12h 45m to drive from Iowa to Tupelo.
There are 34+ hotels available in Tupelo.
What companies run services between Iowa, USA and Tupelo, MS, USA?
You can take a bus from Des Moines to Tupelo via Kansas City, Kansas City Bus Station, St Louis Bus Station, Memphis Bus Station, and Tupelo in around 17h 49m.
- Website
- southwest.com
Flights from Des Moines to Nashville via Chicago Midway
- Ave. Duration
- 3h 35m
- When
- Monday, Thursday, and Friday
- Estimated price
- $110–600
Flights from Omaha to Nashville
- Ave. Duration
- 1h 45m
- When
- Every day
- Estimated price
- $90–550
Flights from Omaha to Nashville via Chicago Midway
- Ave. Duration
- 4h
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $100–600
Flights from Omaha to Nashville via St. Louis
- Ave. Duration
- 4h 20m
- When
- Every day
- Estimated price
- $90–550
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Kansas City to St. Louis
- Ave. Duration
- 5h 40m
- Frequency
- Twice daily
- Estimated price
- $65–160
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Nashville Bus Station to Memphis Bus Station
- Ave. Duration
- 3h 20m
- Frequency
- 4 times a day
- Estimated price
- $30–55
- Website
- Greyhound
Bus from Memphis Bus Station to Tupelo
- Ave. Duration
- 1h 45m
- Frequency
- Twice daily
- Estimated price
- $15–25
- Website
- Greyhound
Bus from Kansas City Bus Station to St Louis Bus Station
- Ave. Duration
- 4h
- Frequency
- 4 times a day
- Estimated price
- $35–65
- Website
- Greyhound
Bus from St Louis Bus Station to Memphis Bus Station
- Ave. Duration
- 5h 30m
- Frequency
- Once daily
- Estimated price
- $45–75
- Website
- Greyhound
Bus from Memphis Bus Station to Tupelo
- Ave. Duration
- 1h 45m
- Frequency
- Twice daily
- Estimated price
- $15–25
- Website
- Greyhound
Bus from Nashville Bus Station to Memphis Bus Station
- Ave. Duration
- 3h 20m
- Frequency
- 4 times a day
- Estimated price
- $30–55
- Website
- Greyhound
Bus from Memphis Bus Station to Tupelo
- Ave. Duration
- 1h 45m
- Frequency
- Twice daily
- Estimated price
- $15–25
- Website
- Greyhound
Bus from Des Moines to Galesburg
- Ave. Duration
- 4h 30m
- Frequency
- Once daily
- Estimated price
- $30–55
- Website
- Greyhound
Bus from Memphis Bus Station to Tupelo
- Ave. Duration
- 1h 45m
- Frequency
- Twice daily
- Estimated price
- $15–25
- Website
- Greyhound
Bus from St Louis Bus Station to Memphis Bus Station
- Ave. Duration
- 5h 30m
- Frequency
- Once daily
- Estimated price
- $45–75
- Website
- Greyhound
Bus from Memphis Bus Station to Tupelo
- Ave. Duration
- 1h 45m
- Frequency
- Twice daily
- Estimated price
- $15–25
- Website
- Greyhound
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
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