There are 4 ways to get from Iquique to Santa Cruz by bus, plane, bus (Flixbus), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus, fly
best- Take the bus from Iquique to Pozo Almontebus
- Take the bus from Pozo Almonte to Iquique Airportbus
- Fly from Diego Aracena International Airport (IQQ) to Comodoro Arturo Merino Benítez International Airport (SCL)plane IQQ - SCL
- Take the bus from Terminal Sur de Santiago to Santa Cruzbus
8h 49m$74–215Bus via Santiago
cheapest- Take the bus from Iquique to Santiagobus FlixBus CL071
- Take the bus from Terminal Sur de Santiago to Terminal de Buses Santa Cruzbus Santiago
27h 38m$42–67Drive 1,883.8 km
- Drive from Iquique to Santa Cruzcar 1,883.8 km
23h 56m$233–336Bus
- Take the bus from Terminal Esmeralda - Turbus to Terminal Alameda - Turbusbus Santiago / ...
- Take the bus from Terminal Sur de Santiago to Santa Cruzbus FlixBus CL027
31h 1m$52–129
Diego Aracena International Airport (IQQ) to Comodoro Arturo Merino Benítez International Airport (SCL) flights
Questions & Answers
The cheapest way to get from Iquique to Santa Cruz is to bus via Santiago which costs $40 - $70 and takes 27h 38m.
The fastest way to get from Iquique to Santa Cruz is to bus and fly which takes 8h 49m and costs $70 - $220.
No, there is no direct bus from Iquique to Santa Cruz. However, there are services departing from Iquique and arriving at Terminal de Buses Santa Cruz via Terminal Sur de Santiago. The journey, including transfers, takes approximately 27h 38m.
The distance between Iquique and Santa Cruz is 1794 km. The road distance is 1883.8 km.
The best way to get from Iquique to Santa Cruz without a car is to bus via Santiago which takes 27h 38m and costs $40 - $70.
It takes approximately 8h 49m to get from Iquique to Santa Cruz, including transfers.
Iquique to Santa Cruz bus services, operated by Flixbus Chile, depart from Iquique station.
Iquique to Santa Cruz bus services, operated by Flixbus Chile, arrive at Santiago station.
Yes, the driving distance between Iquique to Santa Cruz is 1884 km. It takes approximately 23h 56m to drive from Iquique to Santa Cruz.
Book your Iquique to Santa Cruz bus tickets online with Omio.
What companies run services between Iquique, Chile and Santa Cruz, O'Higgins, Chile?
You can take a bus from Iquique to Terminal de Buses Santa Cruz via Santiago and Terminal Sur de Santiago in around 27h 38m.
- Website
- latam.com
Flights from Diego Aracena International Airport to Comodoro Arturo Merino Benítez International Airport
- Ave. Duration
- 2h 14m
- When
- Every day
- Estimated price
- $110–650
- Website
- skyairline.com
Flights from Diego Aracena International Airport to Comodoro Arturo Merino Benítez International Airport
- Ave. Duration
- 2h 14m
- When
- Every day
- Estimated price
- $45–120
- Website
- jetsmart.com
Flights from Diego Aracena International Airport to Comodoro Arturo Merino Benítez International Airport
- Ave. Duration
- 2h 16m
- When
- Every day
- Estimated price
- $50–95
- [email protected]
- Website
- Pullman San Andres
Bus from Iquique to Pozo Almonte
- Ave. Duration
- 1h
- Frequency
- 4 times a day
- Estimated price
- $20–35
- Schedules at
- Pullman San Andres
- Semi Cama
- $20–27
- Cama
- $22–35
- [email protected]
- Website
- Transportes San Antonio
Bus from Iquique to Pozo Almonte
- Ave. Duration
- 1h 20m
- Frequency
- 4 times a day
- Estimated price
- $6–9
- Website
- Transportes San Antonio
- Road
- $6–9
- Website
- Flixbus Chile
Bus from Terminal Sur de Santiago to Santa Cruz
- Ave. Duration
- 2h 40m
- Frequency
- Hourly
- Estimated price
- $19–35
- Schedules at
- Flixbus Chile
Bus from Iquique to Santiago
- Ave. Duration
- 24h 20m
- Frequency
- 4 times a day
- Estimated price
- $180–300
- Schedules at
- Flixbus Chile
Bus from Terminal Sur de Santiago to Santa Cruz
- Ave. Duration
- 2h 40m
- Frequency
- Hourly
- Estimated price
- $19–35
- Schedules at
- Flixbus Chile
- Phone
- +56 600 600 0018
- [email protected]
- Website
- pullmanbus.cl
Bus from Terminal Sur de Santiago to Santa Cruz
- Ave. Duration
- 3h
- Frequency
- 4 times a day
- Estimated price
- $12–35
- Schedules at
- pullmanbus.cl
- Book at
- pullmanbus.cl
- Salón Cama
- $14–35
Bus from Terminal Sur de Santiago to Santa Cruz
- Ave. Duration
- 3h
- Frequency
- 4 times a day
- Estimated price
- $12–35
- Schedules at
- pullmanbus.cl
- Book at
- pullmanbus.cl
- Salón Cama
- $14–35
- Phone
- +56 57 226 9210
- [email protected]
- Website
- Ramos Cholele
Bus from Iquique to Santiago
- Ave. Duration
- 24h
- Frequency
- Twice daily
- Estimated price
- $35–53
- Schedules at
- Ramos Cholele
- Semi cama
- $35–50
- Salón cama
- $49–53
- Phone
- +56967538284
- Website
- kupos.cl
Bus from Iquique to Santiago
- Ave. Duration
- 21h 25m
- Frequency
- Once daily
- Estimated price
- $55
- Book at
- kupos.cl
- [email protected]
- Website
- Expreso Santa Cruz
Bus from Terminal Sur de Santiago to Terminal de Buses Santa Cruz
- Ave. Duration
- 3h
- Frequency
- Every 30 minutes
- Estimated price
- $7
- Schedules at
- Expreso Santa Cruz
- Phone
- +56 22 683 8528
- [email protected]
- Website
- Andimar
Bus from Terminal Sur de Santiago to Terminal de Buses Santa Cruz
- Ave. Duration
- 2h 50m
- Frequency
- Hourly
- Estimated price
- $4–11
- Schedules at
- Andimar
- Semi Cama
- $4–9
- Cama
- $5–11
Bus from Terminal Sur de Santiago to Terminal de Buses Santa Cruz
- Ave. Duration
- 3h 20m
- Frequency
- Every 30 minutes
- Estimated price
- $4–11
- Schedules at
- TranSantin
- Road
- $4–11
- Phone
- +56 2 2666 5505
- [email protected]
- Website
- Buses Jetsur
Bus from Terminal Sur de Santiago to Terminal de Buses Santa Cruz
- Ave. Duration
- 3h 13m
- Frequency
- 4 times a day
- Estimated price
- $10–13
- Website
- Buses Jetsur
- Phone
- +56 22 822 7500
- [email protected]
- Website
- turbus.cl
Bus from Terminal Esmeralda - Turbus to Terminal Alameda - Turbus
- Ave. Duration
- 27h 54m
- Frequency
- 4 times a day
- Estimated price
- $40–95
- Schedules at
- turbus.cl
- Book at
- turbus.cl
- Semi Cama
- $40–60
- Cama
- $70–95
- Premium
- $70–85
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