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How to get fromIrvine to Great Smoky Mountainsby plane, car, bus, or train

Find Transport to Great Smoky Mountains

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There are 6 ways to get from Irvine to Great Smoky Mountains by plane, car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly John Wayne Airport Orange County to Mcghee Tyson Airport, drive

    best
    1. Fly from John Wayne Airport Orange County (SNA) to Mcghee Tyson Airport (TYS)plane plane SNA - TYS
    2. Drive from Mcghee Tyson Airport (TYS) to Great Smoky Mountainscar car
    7h 53m
    $301–1,170

  2. Train to Los Angeles International Airport, fly to Mcghee Tyson Airport, drive

    cheapest
    1. Take the train from Tustin to L.A. Union Stationtrain train
    2. Fly from Los Angeles International Airport (LAX) to Mcghee Tyson Airport (TYS)plane plane LAX - TYS
    3. Drive from Mcghee Tyson Airport (TYS) to Great Smoky Mountainscar car
    11h 6m
    $286–1,141

  3. Bus, drive (Greyhound)

    1. Take the bus from Anaheim to Los Angeles Union Stationbus bus
    2. Take the bus from Los Angeles Union Station to Dallas Bus Stationbus bus
    3. Take the bus from Dallas Bus Station to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to Winston Salem(Trans Center)bus bus
    5. Take the bus from Winston Salem(Trans Center) to Asheville, NCbus bus
    6. Drive from Asheville, NC to Great Smoky Mountainscar car
    2d 16h
    $420–835

  4. Train, bus, drive

    1. Take the train from Tustin to L.A. Union Stationtrain train
    2. Take the train from Los Angeles to New Orleans Union Passenger Terminaltrain train
    3. Take the train from New Orleans Union Passenger Terminal to Greensborotrain train
    4. Take the bus from Greensboro Bus Stop to Asheville, NCbus bus
    5. Drive from Asheville, NC to Great Smoky Mountainscar car
    3d 4h
    $928–2,082

  5. Drive 2,222.5 mi

    1. Drive from Irvine to Great Smoky Mountainscar car 2,222.5 mi
    36h 8m
    $406–586

  6. Fly John Wayne Airport Orange County to Hartsfield-Jackson Atlanta International Airport, drive

    1. Fly from John Wayne Airport Orange County (SNA) to Hartsfield-Jackson Atlanta International Airport (ATL)plane plane SNA - ATL
    2. Drive from Atlanta-Airport-ATL to Great Smoky Mountainscar car
    8h 43m
    $334–875

John Wayne Airport Orange County (SNA) to Mcghee Tyson Airport (TYS) flights

Calendar56Weekly Planes
Duration6h 49mAverage Duration
Ticket$290Cheapest Price
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Questions & Answers

Map of how to get from Irvine to Great Smoky Mountains.ExpandLaunch map view
  • Distance: 1,978.2 mi
  • Duration: 7h 53m

What companies run services between Irvine, CA, USA and Great Smoky Mountains, TN, USA?

There is no direct connection from Irvine to Great Smoky Mountains. However, you can fly to Mcghee Tyson Airport (TYS) then drive to Great Smoky Mountains. Alternatively, you can take a bus from Main-Harvard to Great Smoky Mountains via Artic - Dock 4, Anaheim, Los Angeles Union Station, Dallas Bus Station, Atlanta Bus Station, Winston Salem(Trans Center), and Asheville, NC in around 2d 16h.

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