There are 5 ways to get from Irvine to Indianapolis by plane, bus (Greyhound), train (Amtrak), car, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from John Wayne Airport Orange County
best- Fly from John Wayne Airport Orange County (SNA) to Indianapolis (IND)plane SNA - IND
6h 36m$181–782Train to Los Angeles International Airport, fly
cheapest- Take the train from Tustin to L.A. Union Stationtrain
- Fly from Los Angeles International Airport (LAX) to Indianapolis (IND)plane LAX - IND
7h 56m$178–397Bus (Greyhound)
- Take the bus from Anaheim Regional Transportation Intermodal Center to Montclair Transcenterbus
- Take the bus from Montclair Transcenter to St Louis Bus Stationbus
- Take the bus from St Louis Bus Station to Indianapolis Union Stationbus
2d 1h$336–538Train (Amtrak)
- Take the train from Fullerton Amtrak Station to Chicago Union Stationtrain Southwest Chief
- Take the train from Chicago Union Station to Indianapolistrain Cardinal
2d 2h$552–1,429Drive 2,049 mi
- Drive from Irvine to Indianapoliscar 2,049 mi
32h 48m$374–541
Irvine to Indianapolis by bus (Greyhound)
Comparing Your Travel Options
The cheapest way to get from Irvine to Indianapolis is to train and fly which costs $170 - $400 and takes 7h 56m.
The fastest way to get from Irvine to Indianapolis is to fly which takes 6h 36m and costs $180 - $800.
No, there is no direct bus from Irvine to Indianapolis station. However, there are services departing from Main-Harvard and arriving at Indianapolis Union Station via Anaheim Regional Transportation Intermodal Center, Montclair Transcenter and St Louis Bus Station. The journey, including transfers, takes approximately 2 days 1h.
No, there is no direct train from Irvine to Indianapolis. However, there are services departing from Tustin and arriving at Indianapolis via Fullerton Amtrak Station and Chicago Union Station. The journey, including transfers, takes approximately 2 days 2h.
The distance between Irvine and Indianapolis is 1813 miles. The road distance is 2061 miles.
The best way to get from Irvine to Indianapolis without a car is to bus which takes 2 days 1h and costs $330 - $550.
It takes approximately 6h 36m to get from Irvine to Indianapolis, including transfers.
Irvine to Indianapolis bus services, operated by Greyhound USA, depart from Anaheim Regional Transportation Intermodal Center station.
Irvine to Indianapolis train services, operated by Amtrak, depart from Fullerton Amtrak Station.
The best way to get from Irvine to Indianapolis is to fly which takes 6h 36m and costs $180 - $800. Alternatively, you can bus, which costs $330 - $550 and takes 2 days 1h, you could also train, which costs $550 - $1,500 and takes 2 days 2h.
What companies run services between Irvine, CA, USA and Indianapolis, IN, USA?
Southwest Airlines, United Airlines, and two other airlines fly from John Wayne Airport Orange County (SNA) to Indianapolis (IND) hourly. Alternatively, you can take a bus from Main-Harvard to Indianapolis Union Station via Artic - Dock 4, Anaheim Regional Transportation Intermodal Center, Montclair Transcenter, and St Louis Bus Station in around 2d 1h.
- Website
- southwest.com
Flights from John Wayne Airport Orange County to Indianapolis via Denver
- Ave. Duration
- 5h 57m
- When
- Saturday and Sunday
- Estimated price
- $180–800
Flights from John Wayne Airport Orange County to Indianapolis via Phoenix
- Ave. Duration
- 5h 45m
- When
- Sunday, Monday, Thursday, and Friday
- Estimated price
- $180–800
Flights from John Wayne Airport Orange County to Indianapolis via Las Vegas
- Ave. Duration
- 6h 27m
- When
- Every day
- Estimated price
- $170–800
Flights from John Wayne Airport Orange County to Indianapolis via Austin
- Ave. Duration
- 7h 7m
- When
- Monday to Wednesday
- Estimated price
- $200–900
Flights from Los Angeles International Airport to Indianapolis via Denver
- Ave. Duration
- 5h 57m
- When
- Every day
- Estimated price
- $150–700
Flights from Los Angeles International Airport to Indianapolis via Kansas City
- Ave. Duration
- 6h 20m
- When
- Monday to Friday
- Estimated price
- $150–700
Flights from Los Angeles International Airport to Indianapolis via Dallas
- Ave. Duration
- 7h 2m
- When
- Every day
- Estimated price
- $160–750
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Fullerton Amtrak Station to Chicago Union Station
- Ave. Duration
- 42h 47m
- Frequency
- Once daily
- Estimated price
- $500–1,300
- Website
- Amtrak
Train from Chicago Union Station to Indianapolis
- Ave. Duration
- 4h 54m
- Frequency
- 3 times a week
- Estimated price
- $45–120
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Anaheim Regional Transportation Intermodal Center to Montclair Transcenter
- Ave. Duration
- 1h 35m
- Frequency
- Once daily
- Estimated price
- $9–16
- Website
- Greyhound
Bus from Montclair Transcenter to St Louis Bus Station
- Ave. Duration
- 39h 5m
- Frequency
- Once daily
- Estimated price
- $290–460
- Website
- Greyhound
Bus from St Louis Bus Station to Indianapolis Union Station
- Ave. Duration
- 4h 45m
- Frequency
- 3 times a day
- Estimated price
- $35–60
- Website
- Greyhound
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
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Booking & Getting There
Irvine to Indianapolis bus services, operated by Greyhound USA, arrive at Montclair Transcenter station.
Indianapolis is 3h ahead of Irvine. It is currently 2:20 PM in Irvine and 5:20 PM in Indianapolis.
Irvine to Indianapolis train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between Irvine to Indianapolis is 2061 miles. It takes approximately 32h 48m to drive from Irvine to Indianapolis.
Book your Irvine to Indianapolis train tickets online with Omio.
There are 880+ hotels available in Indianapolis.








