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How to get fromIrvine to La Mesaby train, tram, bus (Greyhound), car, or bus (Greyhound, Flixbus)

Find Transport to La Mesa

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There are 4 ways to get from Irvine to La Mesa by train, tram, bus (Greyhound), car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, tram

    best
    1. Take the train from Irvine to San Diego Old Town Transportation Centertrain train Pacific Surfliner
    2. Take the tram from Old Town Station to 70th Street Stationtram tram Green
    3h 18m
    $33–77

  2. Drive 86.1 mi

    cheapest
    1. Drive from Irvine to La Mesacar car 86.1 mi
    1h 30m
    $16–23

  3. Line 59 bus, bus

    1. Take the bus from University-Ent 3773 Mariposa Villa to The Depot At Santa Ana Dock 3bus bus 59
    2. Take the bus from Santa Ana to San Diegobus bus Los Angeles
    4h 8m
    $22–44

  4. Line 59 bus, bus, line 10 bus

    1. Take the bus from University-Ent 3773 Mariposa Villa to The Depot At Santa Ana Dock 3bus bus 59
    2. Take the bus from Santa Ana Bus Stop to San Diego Greyhound Bus Stopbus bus
    3. Take the bus from Old Town Transit Center to University Av & College Avbus bus 10
    5h 8m
    $19–38

Irvine to La Mesa by train and tram

Calendar91Weekly Services
Duration3h 18mAverage Duration
Ticket$33Cheapest Price
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Questions & Answers

Map of how to get from Irvine to La Mesa.ExpandLaunch map view
  • Distance: 95.5 mi
  • Duration: 3h 18m

What companies run services between Irvine, CA, USA and La Mesa, CA, USA?

You can take a bus from University-Ent 3773 Mariposa Villa to La Mesa Blvd Station via The Depot At Santa Ana Dock 3, Santa Ana, San Diego, and 12th & Imperial Station in around 4h 8m.

Train operators
Bus operators

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