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How to get fromIrvine to Lexingtonby plane, car, bus, or train

Find Transport to Lexington

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There are 7 ways to get from Irvine to Lexington by plane, car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly John Wayne Airport Orange County to Louisville International Airport, drive

    best
    1. Fly from John Wayne Airport Orange County (SNA) to Louisville International Airport (SDF)plane plane SNA - SDF
    2. Drive from Louisville-Airport-SDF to Lexingtoncar car
    7h 4m
    $248–1,019

  2. Fly John Wayne Airport Orange County to Blue Grass Airport

    cheapest
    1. Fly from John Wayne Airport Orange County (SNA) to Blue Grass Airport (LEX)plane plane SNA - LEX
    8h 51m
    $137–569

  3. Bus, drive

    1. Take the bus from Anaheim Regional Transportation Intermodal Center to Los Angeles Union Stationbus bus
    2. Take the bus from Los Angeles Union Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Evansville Bus Stationbus bus
    4. Take the bus from Evansville, IN to Corydon, INbus bus
    5. Drive from Middletown Station @ Target to Lexingtoncar car
    2d 7h
    $480–810

  4. Train, bus, drive via Chicago (Amtrak)

    1. Take the train from Fullerton Amtrak Station to Chicago Union Stationtrain train
    2. Take the bus from Chicago Union Station to Louisville, KYbus bus
    3. Drive from Middletown Station @ Target to Lexingtoncar car
    2d 8h
    $1,271–1,993

  5. Drive  2,145.7 mi

    1. Drive from Irvine to Lexingtoncar car 2,145.7 mi
    34h 29m
    $392–566

  6. Train to Los Angeles International Airport, fly to Covington, drive

    1. Take the train from Tustin to L.A. Union Stationtrain train
    2. Fly from Los Angeles International Airport (LAX) to Covington (CVG)plane plane LAX - CVG
    3. Drive from Covington (CVG) to Lexingtoncar car
    8h 33m
    $231–697

  7. Train, bus, drive

    1. Take the train from Tustin to L.A. Union Stationtrain train
    2. Take the train from Los Angeles to St. Louistrain train
    3. Take the bus from St Louis Bus Station to Evansville Bus Stationbus bus
    4. Take the bus from Evansville, IN to Corydon, INbus bus
    5. Drive from Middletown Station @ Target to Lexingtoncar car
    2d 20h
    $1,441–2,358

John Wayne Airport Orange County (SNA) to Louisville International Airport (SDF) flights

Calendar81Weekly Planes
Duration6h 46mAverage Duration
Ticket$234Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Irvine to Lexington.ExpandLaunch map view
  • Distance: 1,893.8 mi
  • Duration: 7h 4m

What companies run services between Irvine, CA, USA and Lexington, KY, USA?

United Airlines, American Airlines, and Delta fly from John Wayne Airport Orange County (SNA) to Blue Grass Airport (LEX) every 4 hours.

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