There are 6 ways to get from Irvine to Mesquite by plane, shuttle, train, bus, car, or bus (Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly, shuttle
best- Fly from John Wayne Airport Orange County (SNA) to Harry Reid International Airport (LAS)plane SNA - LAS
- Take a shuttle bus from Harry Reid International to Mesquite, NV - Eureka Casino
3h 25m$136–596Drive 347.8 mi
cheapest- Drive from Irvine to Mesquitecar 347.8 mi
5h 39m$64–92Train, bus
- Take the train from Tustin to L.A. Union Stationtrain
- Take the bus from East Los Angeles to Las Vegasbus
- Take the bus from Las Vegas to Mesquite, NVbus
9h 21m$101–154Train, bus via Kingman
- Take the train from Fullerton Amtrak Station to Kingman Stationtrain
- Take the bus from Kingman, AZ to Las Vegasbus
- Take the bus from Las Vegas to Mesquite, NVbus
13h 8m$182–364Train, bus via San Bernardino
- Take the train from Tustin to San Bernardino - Downtowntrain
- Take the bus from San Bernardino to SB Las Vegas at Fashion Show Mallbus
- Take the bus from Harry Reid International to Mesquite, NVbus
10h 31m$81–117Bus
- Take the bus from Anaheim Regional Transportation Intermodal Center to Las Vegas Stripbus FlixBus 2037
- Take the bus from Harry Reid International to Mesquite, NVbus Las Vegas
12h 54m$78–146
Irvine to Mesquite by train, tram, and bus
Questions & Answers
The cheapest way to get from Irvine to Mesquite is to drive which costs $60 - $95 and takes 5h 39m.
The fastest way to get from Irvine to Mesquite is to fly and shuttle which takes 3h 25m and costs $130 - $600.
No, there is no direct bus from Irvine to Mesquite. However, there are services departing from Main-Culver and arriving at Mesquite, NV via Anaheim Regional Transportation Intermodal Center, EB Sands after Las Vegas and Harry Reid International. The journey, including transfers, takes approximately 12h 54m.
The distance between Irvine and Mesquite is 316 miles. The road distance is 349.8 miles.
The best way to get from Irvine to Mesquite without a car is to train and bus which takes 9h 21m and costs $100 - $160.
It takes approximately 3h 25m to get from Irvine to Mesquite, including transfers.
Irvine to Mesquite bus services, operated by Flixbus USA, depart from Anaheim Regional Transportation Intermodal Center station.
Irvine to Mesquite bus services, operated by Flixbus USA, arrive at Las Vegas Strip station.
Yes, the driving distance between Irvine to Mesquite is 350 miles. It takes approximately 5h 39m to drive from Irvine to Mesquite.
There are 43+ hotels available in Mesquite.
What companies run services between Irvine, CA, USA and Mesquite, NV, USA?
You can take a bus from Main-Culver to Mesquite, NV via Artic - Dock 4, Anaheim Regional Transportation Intermodal Center, Las Vegas Strip, EB Sands after Las Vegas, and Harry Reid International in around 12h 54m.
- Website
- southwest.com
Flights from John Wayne Airport Orange County to Harry Reid International Airport
- Ave. Duration
- 1h 13m
- When
- Every day
- Estimated price
- $40–290
- Website
- jsx.com
Flights from John Wayne Airport Orange County to Harry Reid International Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- $40–290
- Website
- delta.com
Flights from John Wayne Airport Orange County to Harry Reid International Airport
- Ave. Duration
- 1h 19m
- When
- Every day
- Estimated price
- $40–290
- Website
- flyfrontier.com
Flights from John Wayne Airport Orange County to Harry Reid International Airport
- Ave. Duration
- 1h 11m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $85–230
- Website
- flybreeze.com
Flights from John Wayne Airport Orange County to Harry Reid International Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- $110–600
- Phone
- (800) 371-LINK (5465)
- Website
- Metrolink Trains
Train from Tustin to L.A. Union Station
- Ave. Duration
- 1h
- Frequency
- Every 3 hours
- Estimated price
- $8–12
- Website
- Metrolink Trains
Train from Tustin to San Bernardino - Downtown
- Ave. Duration
- 1h 31m
- Frequency
- 3 times a day
- Estimated price
- $9–14
- Website
- Metrolink Trains
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Fullerton Amtrak Station to Kingman Station
- Ave. Duration
- 6h 50m
- Frequency
- Once daily
- Estimated price
- $110–240
- Website
- Amtrak
- Phone
- +1 800-933-8320
- [email protected]
- Website
- St. George Shuttle
Shuttle from Harry Reid International to Mesquite, NV - Eureka Casino
- Ave. Duration
- 1h 20m
- Frequency
- Hourly
- Estimated price
- $30–45
- Website
- St. George Shuttle
- Phone
- +1 833 766 3553
- Website
- Tufesa
Bus from East Los Angeles to Las Vegas
- Ave. Duration
- 4h 45m
- Frequency
- Once daily
- Estimated price
- $60–85
- Schedules at
- Tufesa
- Adult One way
- $60–85
Bus from Las Vegas to Mesquite, NV
- Ave. Duration
- 1h 10m
- Frequency
- Once daily
- Estimated price
- $30–55
- Schedules at
- Tufesa
- Adult One way
- $30–55
Bus from Kingman, AZ to Las Vegas
- Ave. Duration
- 1h 25m
- Frequency
- Every 3 hours
- Estimated price
- $35–60
- Schedules at
- Tufesa
- Adult One way
- $35–60
Bus from Las Vegas to Mesquite, NV
- Ave. Duration
- 1h 10m
- Frequency
- Once daily
- Estimated price
- $30–55
- Schedules at
- Tufesa
- Adult One way
- $30–55
- Phone
- +1 602-698-7800
- [email protected]
- Website
- Luxury Coach of America
Bus from San Bernardino to SB Las Vegas at Fashion Show Mall
- Ave. Duration
- 4h 29m
- Frequency
- 5 times a week
- Estimated price
- $45
- Schedules at
- Luxury Coach of America
- Phone
- +1 208-656-8824
- [email protected]
- Website
- Salt Lake Express
Bus from Harry Reid International to Mesquite, NV
- Ave. Duration
- 1h 26m
- Frequency
- Every 3 hours
- Estimated price
- $22–55
- Website
- Salt Lake Express
Bus from Harry Reid International to Mesquite, NV
- Ave. Duration
- 1h 26m
- Frequency
- Every 3 hours
- Estimated price
- $22–55
- Website
- Salt Lake Express
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Anaheim Regional Transportation Intermodal Center to Las Vegas Strip
- Ave. Duration
- 7h 15m
- Frequency
- Twice daily
- Estimated price
- $50–85
- Schedules at
- Flixbus USA
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