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How to get fromIrvine to Palo Altoby plane, train, bus (Greyhound), train (Amtrak), car, or bus

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There are 9 ways to get from Irvine to Palo Alto by plane, train, bus (Greyhound), train (Amtrak), car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly John Wayne Airport Orange County to Norman Y. Mineta San José International Airport, Caltrain

    best
    1. Fly from John Wayne Airport Orange County (SNA) to Norman Y. Mineta San José International Airport (SJC)plane plane SNA - SJC
    2. Take the train from Santa Clara Caltrain Northbound to California Avenue Caltrain Northboundtrain train
    3h 47m
    $509–811

  2. Bus via Westminster, CA - ABC Supermarket

    cheapest
    1. Take the bus from Westminster, CA - ABC Supermarket to San Jose, CA - Huong Lan Sandwichbus bus Westminster
    11h 22m
    $51–69

  3. Bus (Greyhound)

    1. Take the bus from Anaheim Regional Transportation Intermodal Center to San Jose Diridon Stationbus bus Greyhound US0831
    10h 26m
    $72–109

  4. Train

    1. Take the train from Tustin to L.A. Union Stationtrain train OC Line
    2. Take the train from Los Angeles to San Josetrain train Coast Starlight
    12h 40m
    $244–379

  5. Drive  397.8 mi

    1. Drive from Irvine to Palo Altocar car 397.8 mi
    6h 45m
    $68–99

  6. Fly John Wayne Airport Orange County to San Francisco International Airport, Caltrain

    1. Fly from John Wayne Airport Orange County (SNA) to San Francisco International Airport (SFO)plane plane SNA - SFO
    2. Take the train from Millbrae Caltrain Southbound to California Avenue Caltrain Southboundtrain train
    3h 52m
    $115–350

  7. Fly John Wayne Airport Orange County to Oakland International Airport, train

    1. Fly from John Wayne Airport Orange County (SNA) to Oakland International Airport (OAK)plane plane SNA - OAK
    2. Take the train from Oakland Coliseum/Airport Amtrak to Santa Clara Amtraktrain train
    5h 25m
    $238–796

  8. Train, line 62 bus to Long Beach Airport, fly to Norman Y. Mineta San José International Airport, Caltrain

    1. Take the train from Tustin to Norwalk / Santa Fe Springstrain train
    2. Take the bus from Norwalk / Imperial to 226th / Norwalkbus bus
    3. Fly from Long Beach Airport (LGB) to Norman Y. Mineta San José International Airport (SJC)plane plane LGB - SJC
    4. Take the train from Santa Clara Caltrain Northbound to California Avenue Caltrain Northboundtrain train
    6h 14m
    $87–493

  9. Train to Ontario International Airport, fly to Norman Y. Mineta San José International Airport

    1. Take the train from Tustin to Riverside - Downtowntrain train
    2. Fly from Ontario International Airport (ONT) to Norman Y. Mineta San José International Airport (SJC)plane plane ONT - SJC
    6h 12m
    $318–773

Irvine to Palo Alto by bus and train (Greyhound)

Calendar7Weekly Services
Duration10h 26mAverage Duration
Ticket$72Cheapest Price
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Comparing Your Travel Options

Map of how to get from Irvine to Palo Alto.ExpandLaunch map view
  • Distance: 362.2 mi
  • Duration: 3h 47m

What companies run services between Irvine, CA, USA and Palo Alto, CA, USA?

Greyhound USA operates a bus from Anaheim Regional Transportation Intermodal Center to San Jose Diridon Station once daily. Tickets cost $65–100 and the journey takes 7h 50m. Alternatively, you can take a train from Tustin to California Avenue Caltrain Northbound via L.A. Union Station, Los Angeles, San Jose, and San Jose Diridon Caltrain Northbound in around 12h 40m.

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Want to know more about travelling around United States

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Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

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