There are 6 ways to get from Irvine to Palo Alto by plane, bus (Greyhound), train (Amtrak), car, train, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Norman Y. Mineta San José International Airport
best- Fly from John Wayne Airport Orange County (SNA) to Norman Y. Mineta San José International Airport (SJC)plane SNA - SJC
2h 16m$200–796Bus via Westminster, CA - ABC Supermarket
cheapest- Take the bus from Westminster, CA - ABC Supermarket to San Jose, CA - Huong Lan Sandwichbus Westminster
11h 22m$51–139Bus
- Take the bus from Anaheim Regional Transportation Intermodal Center to San Jose Diridon Stationbus Greyhound US0831
10h 21m$62–129Train
- Take the train from Tustin to L.A. Union Stationtrain OC Line
- Take the train from Los Angeles to San Josetrain Coast Starlight
12h 40m$144–299Drive 397.8 mi
- Drive from Irvine to Palo Altocar 397.8 mi
6h 45m$73–105Fly to San Francisco International Airport, Caltrain
- Fly from John Wayne Airport Orange County (SNA) to San Francisco International Airport (SFO)plane SNA - SFO
- Take the train from Millbrae Caltrain Southbound to California Avenue Caltrain Southboundtrain
2h 29m$193–733
Irvine to Palo Alto by bus and train
Questions & Answers
The cheapest way to get from Irvine to Palo Alto is to bus via Westminster, CA - ABC Supermarket which costs $50 - $140 and takes 11h 22m.
The fastest way to get from Irvine to Palo Alto is to fly which takes 2h 16m and costs $200 - $800.
No, there is no direct bus from Irvine to Palo Alto station. However, there are services departing from Main-Harvard and arriving at San Jose Diridon Station via Anaheim Regional Transportation Intermodal Center. The journey, including transfers, takes approximately 10h 21m.
No, there is no direct train from Irvine to Palo Alto. However, there are services departing from Tustin and arriving at California Avenue Caltrain Northbound via Los Angeles and San Jose Diridon Caltrain Northbound. The journey, including transfers, takes approximately 12h 40m.
The distance between Irvine and Palo Alto is 362 miles. The road distance is 400.1 miles.
The best way to get from Irvine to Palo Alto without a car is to bus which takes 10h 21m and costs $60 - $130.
It takes approximately 2h 16m to get from Irvine to Palo Alto, including transfers.
Irvine to Palo Alto bus services, operated by Jefferson Lines, depart from Anaheim Regional Transportation Intermodal Center station.
Irvine to Palo Alto train services, operated by Metrolink Trains, depart from Tustin station.
The best way to get from Irvine to Palo Alto is to fly which takes 2h 16m and costs $200 - $800. Alternatively, you can bus, which costs $60 - $130 and takes 10h 21m, you could also train, which costs $140 - $300 and takes 12h 40m.
What companies run services between Irvine, CA, USA and Palo Alto, CA, USA?
Southwest Airlines flies from John Wayne Airport Orange County (SNA) to Norman Y. Mineta San José International Airport (SJC) every 4 hours. Alternatively, Jefferson Lines operates a bus from Anaheim Regional Transportation Intermodal Center to San Jose Diridon Station once daily. Tickets cost $85–130 and the journey takes 7h 45m. Greyhound USA also services this route once daily.
- Website
- southwest.com
Flights from John Wayne Airport Orange County to Norman Y. Mineta San José International Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- $55–340
Flights from John Wayne Airport Orange County to San Francisco International Airport via Las Vegas
- Ave. Duration
- 3h 57m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $50–270
- Website
- alaskaair.com
Flights from John Wayne Airport Orange County to San Francisco International Airport
- Ave. Duration
- 1h 36m
- When
- Every day
- Estimated price
- $100–300
- Website
- united.com
Flights from John Wayne Airport Orange County to San Francisco International Airport
- Ave. Duration
- 1h 36m
- When
- Every day
- Estimated price
- $35–230
- Website
- flyfrontier.com
Flights from John Wayne Airport Orange County to San Francisco International Airport
- Ave. Duration
- 1h 37m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $160–290
- Phone
- (800) 371-LINK (5465)
- Website
- metrolinktrains.com
Train from Tustin to L.A. Union Station
- Ave. Duration
- 1h
- Frequency
- Every 3 hours
- Estimated price
- $8–12
- Website
- https://metrolinktrains.com
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Los Angeles to San Jose
- Ave. Duration
- 9h 55m
- Frequency
- Once daily
- Estimated price
- $130–280
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 800-660-4287
- Website
- caltrain.com
Train from Millbrae Caltrain Southbound to California Avenue Caltrain Southbound
- Ave. Duration
- 31 min
- Frequency
- Every 30 minutes
- Estimated price
- $5–7
- Website
- https://www.caltrain.com
- Schedules at
- https://www.caltrain.com/?active_tab=route_explorer_tab
- One-way Adult
- $5–7
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Anaheim Regional Transportation Intermodal Center to San Jose Diridon Station
- Ave. Duration
- 7h 45m
- Frequency
- Once daily
- Estimated price
- $85–130
- Book at
- https://www.jeffersonlines.com
- Adult
- $85–130
Bus from Westminster, CA - ABC Supermarket to San Jose, CA - Huong Lan Sandwich
- Ave. Duration
- 7h 15m
- Frequency
- Once daily
- Estimated price
- $85–130
- Book at
- https://www.jeffersonlines.com
- Adult
- $85–130
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Anaheim Regional Transportation Intermodal Center to San Jose Diridon Station
- Ave. Duration
- 7h 50m
- Frequency
- Once daily
- Estimated price
- $55–120
- Website
- https://www.greyhound.com/
- Phone
- +1 714-839-3500
- [email protected]
- Website
- xedohoang.com
Bus from Westminster, CA - ABC Supermarket to San Jose, CA - Huong Lan Sandwich
- Ave. Duration
- 6h 45m
- Frequency
- Once daily
- Estimated price
- $45–60
- Book at
- https://www.gotobus.com/hoangexpress/
- Website
- https://xedohoang.com/en
- Adult One-way
- $45–60
- Phone
- +1 714-839-3500
- [email protected]
- Website
- xedohoang.com
Bus from Westminster, CA - ABC Supermarket to San Jose, CA - Huong Lan Sandwich
- Ave. Duration
- 7h 15m
- Frequency
- Once daily
- Estimated price
- $48–52
- Schedules at
- xedohoang.com
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide
More Questions & Answers
Irvine to Palo Alto bus services, operated by Jefferson Lines, arrive at San Jose Diridon Station.
Irvine to Palo Alto train services, operated by Metrolink Trains, arrive at L.A. Union Station.
Yes, the driving distance between Irvine to Palo Alto is 400 miles. It takes approximately 6h 45m to drive from Irvine to Palo Alto.
There are 499+ hotels available in Palo Alto.



















