There are 3 ways to get from Irvine to Santa Fe Depot by train (Amtrak), bus (Flixbus), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train (Amtrak)
best- Take the train from Irvine to San Diegotrain Pacific Surfliner
2h 57m$32–63Drive 82.8 mi
cheapest- Drive from Irvine to Santa Fe Depotcar 82.8 mi
1h 27m$16–22Line 59 bus, bus
- Take the bus from University-Ent 3773 Mariposa Villa to The Depot At Santa Ana Dock 3bus 59
- Take the bus from Santa Ana Bus Stop to San Diegobus FlixBus 2017
3h 38m$32–47
Irvine to Santa Fe Depot by train (Amtrak)
Questions & Answers
The cheapest way to get from Irvine to Santa Fe Depot is to drive which costs $15 - $22 and takes 1h 27m.
The fastest way to get from Irvine to Santa Fe Depot is to drive which takes 1h 27m and costs $15 - $22.
No, there is no direct bus from Irvine to Santa Fe Depot. However, there are services departing from University-Ent 3773 Mariposa Villa and arriving at San Diego via Santa Ana Bus Stop. The journey, including transfers, takes approximately 3h 38m.
No, there is no direct train from Irvine to Santa Fe Depot. However, there are services departing from Tustin and arriving at San Diego via Irvine. The journey, including transfers, takes approximately 2h 57m.
The distance between Irvine and Santa Fe Depot is 88 miles. The road distance is 83.3 miles.
The best way to get from Irvine to Santa Fe Depot without a car is to train which takes 2h 57m and costs $30 - $65.
It takes approximately 2h 57m to get from Irvine to Santa Fe Depot, including transfers.
Irvine to Santa Fe Depot bus services, operated by OCTA, depart from University-Ent 3773 Mariposa Villa station.
Irvine to Santa Fe Depot train services, operated by Amtrak, depart from Irvine station.
The best way to get from Irvine to Santa Fe Depot is to train which takes 2h 57m and costs $30 - $65. Alternatively, you can line 59 bus and bus, which costs $30 - $50 and takes 3h 38m.
What companies run services between Irvine, CA, USA and Santa Fe Depot, San Diego County, CA, USA?
Amtrak operates a train from Irvine to San Diego hourly. Tickets cost $26–55 and the journey takes 1h 55m. Alternatively, you can take a bus from University-Ent 3773 Mariposa Villa to Santa Fe Depot via Santa Ana Bus Stop and San Diego in around 3h 38m.
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Irvine to San Diego
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- $26–55
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 714-560-6282
- Website
- octa.net
Bus from University-Ent 3773 Mariposa Villa to The Depot At Santa Ana Dock 3
- Ave. Duration
- 44 min
- Frequency
- Hourly
- Estimated price
- $2
- Schedules at
- octa.net
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Santa Ana Bus Stop to San Diego
- Ave. Duration
- 1h 45m
- Frequency
- Once daily
- Estimated price
- $14–24
- Schedules at
- flixbus.com
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Santa Ana Bus Stop to San Diego
- Ave. Duration
- 1h 45m
- Frequency
- Once daily
- Estimated price
- $30–45
- Book at
- https://www.jeffersonlines.com
- Adult
- $30–45
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More Questions & Answers
Irvine to Santa Fe Depot bus services, operated by OCTA, arrive at The Depot At Santa Ana Dock 3 station.
Irvine to Santa Fe Depot train services, operated by Amtrak, arrive at San Diego station.
Yes, the driving distance between Irvine to Santa Fe Depot is 83 miles. It takes approximately 1h 27m to drive from Irvine to Santa Fe Depot.
There are 2125+ hotels available in Santa Fe Depot.











