There are 7 ways to get from Irwin to Chicago by bus, plane, train (Amtrak), bus (Greyhound, Flixbus), car, or bus (Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Line 4 bus, bus to Pittsburgh International Airport, fly to Chicago Midway International Airport
best- Take the bus from Pennsylvania Ave + Main St to Grant St + Liberty Ave FSbus
- Take the bus from Seventh Ave + Smithfield St to Pittsburgh International Airportbus
- Fly from Pittsburgh International Airport (PIT) to Chicago Midway International Airport (MDW)plane PIT - MDW
5h 48mBus to Johnstown-Cambria County Airport, fly to Chicago O'Hare International Airport
cheapest- Take the bus from Greensburg Westmoreland Transit Ctr to Johnstown Bus Stopbus
- Fly from Johnstown-Cambria County Airport (JST) to Chicago O'Hare International Airport (ORD)plane JST - ORD
6h 55m$68–320Train (Amtrak)
- Take the train from Pittsburgh Amtrak Station to Chicago Union Stationtrain Floridian
11h 56m$111–286Bus
- Take the bus from Pittsburgh Intermodal Station to Chicago Bus Stationbus Greyhound US0164
12h 15m$71–126Drive 478.6 mi
- Drive from Irwin to Chicagocar 478.6 mi
7h 55m$88–127Line 4 bus, bus to Pittsburgh International Airport, fly to Chicago O'Hare International Airport
- Take the bus from Pennsylvania Ave + Main St to Grant St + Liberty Ave FSbus
- Take the bus from Seventh Ave + Smithfield St to Pittsburgh International Airportbus
- Fly from Pittsburgh International Airport (PIT) to Chicago O'Hare International Airport (ORD)plane PIT - ORD
6h 10mBus via Chicago (Flixbus)
- Take the bus from Pittsburgh Intermodal Station to Chicagobus FlixBus N2640
13h 32m$83–131
Irwin to Chicago by bus and train (Amtrak)
Comparing Your Travel Options
The cheapest way to get from Irwin to Chicago is to bus which costs $70 - $130 and takes 12h 15m.
The fastest way to get from Irwin to Chicago is to bus and fly which takes 6h 55m and costs $65 - $320.
No, there is no direct bus from Irwin to Chicago station. However, there are services departing from Pennsylvania Ave + Main St and arriving at Chicago Bus Station via Pittsburgh Intermodal Station. The journey, including transfers, takes approximately 12h 15m.
No, there is no direct train from Irwin station to Chicago station. However, there are services departing from Pittsburgh Amtrak Station and arriving at Chicago Union Station via . The journey, including transfers, takes approximately 11h 56m.
The distance between Irwin and Chicago is 459 miles. The road distance is 481.4 miles.
The best way to get from Irwin to Chicago without a car is to train which takes 11h 56m and costs $110 - $290.
It takes approximately 5h 48m to get from Irwin to Chicago, including transfers.
Irwin to Chicago bus services, operated by Greyhound USA, depart from Pittsburgh Intermodal Station.
Irwin to Chicago train services, operated by Amtrak, depart from Pittsburgh Amtrak Station.
The best way to get from Irwin to Chicago is to train which takes 11h 56m and costs $110 - $290. Alternatively, you can bus, which costs $70 - $130 and takes 12h 15m.
What companies run services between Irwin, PA, USA and Chicago, IL, USA?
Amtrak operates a train from Pittsburgh Amtrak Station to Chicago Union Station once daily. Tickets cost $110–280 and the journey takes 9h 46m. Alternatively, Greyhound USA operates a bus from Pittsburgh Intermodal Station to Chicago Bus Station twice daily. Tickets cost $75–120 and the journey takes 10h 5m. Flixbus USA also services this route once daily.
- Website
- united.com
Flights from Pittsburgh International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 47m
- When
- Every day
- Estimated price
- $50–330
Flights from Johnstown-Cambria County Airport to Chicago O'Hare International Airport
- Ave. Duration
- 2h 5m
- When
- Every day
- Estimated price
- $45–280
Flights from Johnstown-Cambria County Airport to Chicago O'Hare International Airport via Washington Dulles
- Ave. Duration
- 4h 23m
- When
- Every day
- Estimated price
- $55–310
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Pittsburgh Amtrak Station to Chicago Union Station
- Ave. Duration
- 9h 46m
- Frequency
- Once daily
- Estimated price
- $110–280
- Website
- Amtrak
- Phone
- +1-724-834-9282
- Website
- Westmoreland Transit
Bus from Pennsylvania Ave + Main St to Grant St + Liberty Ave FS
- Ave. Duration
- 1h 10m
- Frequency
- Every 4 hours
- Estimated price
- $1–6
- Website
- Westmoreland Transit
- Schedules at
- Westmoreland Transit Fixed-Route Bus Schedules
- Children 6-12
- $1–3
- Adults 13+
- $2–6
Bus from Pennsylvania Ave + Main St to Grant St + Liberty Ave FS
- Ave. Duration
- 1h 10m
- Frequency
- Every 4 hours
- Estimated price
- $1–6
- Website
- Westmoreland Transit
- Schedules at
- Westmoreland Transit Fixed-Route Bus Schedules
- Children 6-12
- $1–3
- Adults 13+
- $2–6
Want to know more about travelling around United States
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Booking & Getting There
Irwin to Chicago bus services, operated by Greyhound USA, arrive at Chicago Bus Station.
Chicago is 1h behind Irwin. It is currently 4:07 AM in Irwin and 3:07 AM in Chicago.
Irwin to Chicago train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between Irwin to Chicago is 481 miles. It takes approximately 7h 55m to drive from Irwin to Chicago.
There are 1280+ hotels available in Chicago.