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How to get fromIsernia to Brusselsby train, plane, train (Trenitalia, TGV, Eurostar), bus, car, or car train

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There are 11 ways to get from Isernia to Brussels by train, plane, train (Trenitalia, TGV, Eurostar), bus, car, or car train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Naples Airport, fly to Brussels Airport

    best
    1. Take the train from Isernia to Casertatrain train
    2. Fly from Naples Airport (NAP) to Brussels Airport (BRU)plane plane NAP - BRU
    7h 9m
    €80–216

  2. Bus, train to Abruzzo Airport, fly to Brussels South Charleroi Airport, train

    cheapest
    1. Take the bus from Isernia to Montenero Bivio SS16bus bus
    2. Take the train from Montenero-Petacciato to Pescara Porta Nuovatrain train
    3. Fly from Abruzzo Airport (PSR) to Brussels South Charleroi Airport (CRL)plane plane PSR - CRL
    4. Take the train from Charleroi-Central to Bruxelles-Centraltrain train
    9h 32m
    €67–298

  3. Train

    1. Take the train from Isernia to Roma Terminitrain train Re
    2. Take the train from Roma Termini to Milano Centraletrain train
    3. Take the train from Milano Centrale to Torino Porta di Susatrain train
    4. Take the train from Torino Porta Susa to Paris Gare De Lyontrain train Tgv
    5. Take the train from Paris Nord to Brussel-Zuid / Bruxelles-Miditrain train
    15h 14m
    €246–634

  4. Bus

    1. Take the bus from Isernia to Casello - A1 Ingresso Caianellobus bus 6
    2. Take the bus from Casello - A1 Ingresso Caianello to Bruxelles - Rue du Progrèsbus bus
    22h 42m

  5. Drive 1,580.2 km

    1. Drive from Isernia to Brusselscar car 1,580.2 km
    16h 10m
    €248–358

  6. Train to Fiumicino International Airport, fly to Brussels Airport

    1. Take the train from Isernia to Roma Terminitrain train
    2. Fly from Fiumicino International Airport (FCO) to Brussels Airport (BRU)plane plane FCO - BRU
    7h 26m
    €68–218

  7. Train to Naples Airport, fly to Brussels South Charleroi Airport, train

    1. Take the train from Isernia to Casertatrain train
    2. Fly from Naples Airport (NAP) to Brussels South Charleroi Airport (CRL)plane plane NAP - CRL
    3. Take the train from Charleroi-Central to Bruxelles-Centraltrain train
    8h 22m
    €75–275

  8. Train to Fiumicino International Airport, fly to Brussels South Charleroi Airport, train

    1. Take the train from Isernia to Roma Terminitrain train
    2. Fly from Fiumicino International Airport (FCO) to Brussels South Charleroi Airport (CRL)plane plane FCO - CRL
    3. Take the train from Charleroi-Central to Bruxelles-Centraltrain train
    8h 50m
    €83–237

  9. Train to Fiumicino International Airport, fly to Eindhoven Airport, train

    1. Take the train from Isernia to Roma Terminitrain train
    2. Fly from Fiumicino International Airport (FCO) to Eindhoven Airport (EIN)plane plane FCO - EIN
    3. Take the train from Eindhoven Centraal to Bredatrain train
    4. Take the train from Breda to Bruxelles-Centraltrain train
    10h 19m
    €110–344

  10. Bus via Bologna

    1. Take the bus from Isernia to Bologna Centralebus bus 433
    2. Take the bus from Bologna to Brussels-North Stationbus bus
    28h

  11. Drive, car train

    1. Drive from Isernia to Kufsteincar car
    2. Take the car train from Kufstein to Kassel-Wilhelmshöhecartrain train
    3. Drive from Kassel-Wilhelmshöhe to Brusselscar car
    19h 59m
    €312–442

Naples Airport (NAP) to Brussels Airport (BRU) flights

Calendar41Weekly Planes
Duration4h 28mAverage Duration
Ticket€63Cheapest Price
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Questions & Answers

Map of how to get from Isernia to Brussels.ExpandLaunch map view
  • Distance: 1,475.4 km
  • Duration: 7h 9m

What companies run services between Isernia, Italy and Brussels, Belgium?

You can take a train from Isernia to Brussel-Zuid / Bruxelles-Midi via Roma Termini, Milano Centrale, Torino Porta Susa, Paris Gare de Lyon, and Paris Nord in around 15h 14m. Alternatively, you can take a bus from Isernia to Bruxelles - Rue du Progrès via Casello - A1 Ingresso Caianello in around 22h 42m.

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