Rome2Rio

How to get fromIsernia to Florenceby train (Trenitalia), bus, car, train, or plane

Find Transport to Florence

See all options

There are 9 ways to get from Isernia to Florence by train (Trenitalia), bus, car, train, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Isernia to Roma Tiburtinatrain train Re
    2. Take the train from Roma Tiburtina to Firenze Santa Maria Novellatrain train 8134 / ...
    4h 9m
    €53–102

  2. Bus via Rome

    cheapest
    1. Take the bus from Isernia to Roma, Autostazione Tiburtinabus bus Campobasso / ...
    2. Take the bus from Roma, Autostazione Tiburtina to Florence Villa Constanza Bus Stationbus bus 510 / ...
    5h 50m
    €26–69

  3. Drive 427.8 km

    1. Drive from Isernia to Florencecar car 427.8 km
    4h 12m
    €67–97

  4. Train to Fiumicino International Airport, fly to Florence Peretola Airport

    1. Take the train from Isernia to Roma Terminitrain train
    2. Fly from Fiumicino International Airport (FCO) to Florence Peretola Airport (FLR)plane plane FCO - FLR
    5h 25m
    €88–236

  5. Train via Rome (Trenitalia)

    1. Take the train from Isernia to Roma Terminitrain train Re
    2. Take the train from Roma Termini to Firenze S.M.N.train train Fr
    4h 13m
    €51–117

  6. Train, bus

    1. Take the train from Isernia to Cassinotrain train Re
    2. Take the bus from Cassino to Florence - Villa Costanzabus bus
    6h 56m
    €34–52

  7. Bus

    1. Take the bus from Isernia to Florence Villa Constanza Bus Stationbus bus 433
    9h 55m
    €50–90

  8. Train to Naples Airport, fly to Florence Peretola Airport

    1. Take the train from Isernia to Casertatrain train
    2. Fly from Naples Airport (NAP) to Florence Peretola Airport (FLR)plane plane NAP - FLR
    7h 3m
    €100–224

  9. Train to Fiumicino International Airport, fly to Bologna Guglielmo Marconi Airport, train

    1. Take the train from Isernia to Roma Terminitrain train
    2. Fly from Fiumicino International Airport (FCO) to Bologna Guglielmo Marconi Airport (BLQ)plane plane FCO - BLQ
    3. Take the train from Bologna Centrale to Firenze S.M.N.train train
    5h 58m
    €75–201

Isernia to Florence by train

Calendar12Weekly Trains
Duration4h 9mAverage Duration
Ticket€53Cheapest Price
See schedules

Questions & Answers

Map of how to get from Isernia to Florence.ExpandLaunch map view
  • Distance: 441.4 km
  • Duration: 4h 9m

What companies run services between Isernia, Italy and Florence, Italy?

You can take a train from Isernia to Firenze Santa Maria Novella via Roma Tiburtina in around 4h 9m. Alternatively, you can take a bus from Isernia to Florence Villa Constanza Bus Station via Roma, Autostazione Tiburtina in around 5h 50m.

Airlines
Train operators
Bus operators

Want to know more about travelling around Italy

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Italy Travel Guides

Read the travel guideItaly Travel Guides

More Questions & Answers