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How to get fromIsernia to Florenceby train (Trenitalia), bus, car, train, or plane

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There are 7 ways to get from Isernia to Florence by train (Trenitalia), bus, car, train, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Isernia to Roma Terminitrain train Re
    2. Take the train from Roma Termini to Firenze Santa Maria Novellatrain train 8134 / ...
    4h 8m
    €52–80
  2. Bus via Rome

    cheapest
    1. Take the bus from Isernia to Roma, Autostazione Tiburtinabus bus Campobasso / ...
    2. Take the bus from Roma, Autostazione Tiburtina to Florence Villa Constanza Bus Stationbus bus 510 / ...
    5h 52m
    €23–63
  3. Drive  427.8 km

    1. Drive from Isernia to Florencecar car 427.8 km
    4h 12m
    €78–112
  4. Train, fly to Florence Peretola Airport

    1. Take the train from Isernia to Roma Terminitrain train
    2. Fly from Fiumicino International Airport (FCO) to Florence Peretola Airport (FLR)plane plane FCO - FLR
    5h 12m
    €87–238
  5. Train via Firenze S.M.N.

    1. Take the train from Isernia to Roma Terminitrain train Re
    2. Take the train from Roma Termini to Firenze S.M.N.train train Fr
    4h 9m
    €51–90
  6. Bus

    1. Take the bus from Isernia to Florence Villa Constanza Bus Stationbus bus 433
    9h 55m
    €55–85
  7. Train, fly to Bologna Guglielmo Marconi Airport

    1. Take the train from Isernia to Roma Terminitrain train
    2. Fly from Fiumicino International Airport (FCO) to Bologna Guglielmo Marconi Airport (BLQ)plane plane FCO - BLQ
    3. Take the train from Bologna Centrale to Firenze S.M.N.train train
    6h 1m
    €90–237

Isernia to Florence by train

Calendar40Weekly Trains
Duration4h 8mAverage Duration
Ticket€52Cheapest Price
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Comparing Your Travel Options

What companies run services between Isernia, Italy and Florence, Italy?

You can take a train from Isernia to Firenze Santa Maria Novella via Roma Termini in around 4h 8m. Alternatively, you can take a bus from Isernia to Florence Villa Constanza Bus Station via Roma, Autostazione Tiburtina in around 5h 52m.

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