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How to get fromIsernia to Palermoby train, plane, car, ferry, bus, or train (Trenitalia)

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There are 9 ways to get from Isernia to Palermo by train, plane, car, ferry, bus, or train (Trenitalia)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Naples Airport, fly to Palermo Airport

    best
    1. Take the train from Isernia to Casertatrain train
    2. Fly from Naples Airport (NAP) to Palermo Airport (PMO)plane plane NAP - PMO
    5h 20m
    €40–188

  2. Bus via Caserta

    cheapest
    1. Take the bus from Isernia to Caserta Terminal Busbus bus 433
    2. Take the bus from Caserta pzza Garibaldi to Palermo Terminal Busbus bus Autoservizi Salemi S201
    12h
    €36–55

  3. Drive, ferry

    1. Drive from Isernia to Naples Beverellocar car
    2. Take the ferry from Naples Beverello to Port of Palermoferry ferry
    9h 2m
    €52–90

  4. Train, ferry via Messina

    1. Take the train from Isernia to Napoli Afragolatrain train Re
    2. Take the train from Napoli Afragola to Villa S.Giovannitrain train Fr
    3. Take the ferry from Villa S.Giovanni to Messina Marittimaferry ferry V1 / ...
    4. Take the train from Messina Centrale to Palermo Centraletrain train Re
    11h

  5. Train to Fiumicino International Airport, fly to Palermo Airport

    1. Take the train from Isernia to Roma Terminitrain train
    2. Fly from Fiumicino International Airport (FCO) to Palermo Airport (PMO)plane plane FCO - PMO
    5h 59m
    €47–169

  6. Train to Fiumicino International Airport, fly to Trapani Airport, bus

    1. Take the train from Isernia to Roma Terminitrain train
    2. Fly from Fiumicino International Airport (FCO) to Trapani Airport (TPS)plane plane FCO - TPS
    3. Take the bus from Trapani Birgi Airport to Palermo Via Belgio/Via dei Nebrodibus bus
    7h 36m
    €72–243

  7. Train, ferry

    1. Take the train from Isernia to Napoli Centraletrain train Re
    2. Take the ferry from Naples Beverello to Port of Palermoferry ferry
    10h 41m
    €52–94

  8. Train (Trenitalia)

    1. Take the train from Isernia to Napoli Centraletrain train Re
    2. Take the train from Napoli Centrale to Palermo Centraletrain train Ic
    12h 44m
    €87–177

  9. Bus

    1. Take the bus from Isernia to Casello - A1 Ingresso Caianellobus bus 6
    2. Take the bus from Casello - A1 Ingresso Caianello to Palermo Piazza Cairolibus bus
    17h 55m
    €172–242

Naples Airport (NAP) to Palermo Airport (PMO) flights

Calendar32Weekly Planes
Duration1h 1mAverage Duration
Ticket€16Cheapest Price
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Questions & Answers

Map of how to get from Isernia to Palermo.ExpandLaunch map view
  • Distance: 464.5 km
  • Duration: 5h 20m

What companies run services between Isernia, Italy and Palermo, Italy?

You can take a bus from Isernia to Palermo Terminal Bus via Caserta Terminal Bus and Caserta pzza Garibaldi in around 12h. Alternatively, you can take a train from Isernia to Palermo Notarbartolo via Napoli Centrale and Palermo Centrale in around 12h 44m.

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