There are 5 ways to get from Isernia to Perugia by train (Trenitalia), bus, car, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train via Foligno (Trenitalia)
best- Take the train from Isernia to Roma Terminitrain Re
- Take the train from Roma Termini to Folignotrain 4160 / ...
5h 29m€43–90Bus
cheapest- Take the bus from Isernia to Roma, Autostazione Tiburtinabus Campobasso / ...
- Take the bus from Roma, Autostazione Tiburtina to Perugiabus 538 / ...
5h 30m€19–47Drive 324.6 km
- Drive from Isernia to Perugiacar 324.6 km
3h 30m€51–74Train (Trenitalia)
- Take the train from Isernia to Roma Terminitrain Re
- Take the train from Roma Termini to Perugiatrain 4730 / ...
6h 2m€43–81Train, bus
- Take the train from Isernia to Roma Terminitrain Re
- Take the bus from Rome Tiburtina Largo Mazzoni to Perugia Piazza Partigianibus
6h 26m€32–50
Isernia to Perugia by train (Trenitalia)
Questions & Answers
The cheapest way to get from Isernia to Perugia is to bus which costs €18 - €50 and takes 5h 30m.
The fastest way to get from Isernia to Perugia is to drive which takes 3h 30m and costs €50 - €75.
No, there is no direct bus from Isernia to Perugia. However, there are services departing from Isernia and arriving at Perugia via Roma, Autostazione Tiburtina. The journey, including transfers, takes approximately 5h 30m.
No, there is no direct train from Isernia to Perugia. However, there are services departing from Isernia and arriving at Perugia via Roma Termini and Foligno. The journey, including transfers, takes approximately 5h 29m.
The distance between Isernia and Perugia is 375 km. The road distance is 324.6 km.
The best way to get from Isernia to Perugia without a car is to train via Foligno which takes 5h 29m and costs €40 - €95.
It takes approximately 5h 29m to get from Isernia to Perugia, including transfers.
Isernia to Perugia bus services, operated by ATM Azienda di Trasporti Molisana S.p.A., depart from Isernia station.
Isernia to Perugia train services, operated by Trenitalia, depart from Isernia station.
The best way to get from Isernia to Perugia is to train via Foligno which takes 5h 29m and costs €40 - €95. Alternatively, you can bus, which costs €18 - €50 and takes 5h 30m.
What companies run services between Isernia, Italy and Perugia, Italy?
You can take a train from Isernia to Perugia via Roma Termini and Foligno in around 5h 29m. Alternatively, you can take a bus from Isernia to Perugia via Roma, Autostazione Tiburtina in around 5h 30m.
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Isernia to Roma Termini
- Ave. Duration
- 2h 24m
- Frequency
- Every 3 hours
- Estimated price
- €23–40
- Website
- Trenitalia
Train from Roma Termini to Foligno
- Ave. Duration
- 1h 47m
- Frequency
- Hourly
- Estimated price
- €18–30
- Website
- Trenitalia
Train from Isernia to Roma Termini
- Ave. Duration
- 2h 24m
- Frequency
- Every 3 hours
- Estimated price
- €23–40
- Website
- Trenitalia
Train from Roma Termini to Perugia
- Ave. Duration
- 2h 38m
- Frequency
- Every 3 hours
- Estimated price
- €23–40
- Website
- Trenitalia
Train from Isernia to Roma Termini
- Ave. Duration
- 2h 24m
- Frequency
- Every 3 hours
- Estimated price
- €23–40
- Website
- Trenitalia
- Phone
- +39 0874 64744
- [email protected]
- Website
- atm-molise.it
Bus from Isernia to Roma, Autostazione Tiburtina
- Ave. Duration
- 2h 10m
- Frequency
- 3 times a day
- Estimated price
- €8–13
- Schedules at
- atm-molise.it
Want to know more about travelling around Italy
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Italy Travel Guides
Read the travel guide
Want to know more about Flixbus?
Read the travel guide
More Questions & Answers
Isernia to Perugia bus services, operated by ATM Azienda di Trasporti Molisana S.p.A., arrive at Roma, Autostazione Tiburtina station.
Isernia to Perugia train services, operated by Trenitalia, arrive at Roma Termini station.
Yes, the driving distance between Isernia to Perugia is 325 km. It takes approximately 3h 30m to drive from Isernia to Perugia.
Book your Isernia to Perugia train tickets online with Omio.
Book your Isernia to Perugia bus tickets online with Omio and FlixBus.
There are 2176+ hotels available in Perugia.