There are 9 ways to get from Isernia to Pisa by train (Trenitalia), bus, car, train, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train (Trenitalia)
best- Take the train from Isernia to Roma Terminitrain Re
- Take the train from Roma Termini to Pisa Centraletrain Fa / ...
5h 39m€57–110Train, bus
cheapest- Take the train from Isernia to Cassinotrain Re
- Take the bus from Cassino to Pisabus
8h 7m€36–53Bus
- Take the bus from Isernia to Roma, Autostazione Tiburtinabus Campobasso / ...
- Take the bus from Roma, Autostazione Tiburtina to Pisabus N1508 / ...
7h 45m€38–68Drive 507.2 km
- Drive from Isernia to Pisacar 507.2 km
5h 4m€83–119Train to Naples Airport, fly to Pisa International Airport
- Take the train from Isernia to Casertatrain
- Fly from Naples Airport (NAP) to Pisa International Airport (PSA)plane NAP - PSA
6h 42m€83–269Train via Rome (Trenitalia)
- Take the train from Isernia to Roma Tiburtinatrain Re
- Take the train from Roma Tiburtina to Pisa Centraletrain Fa
5h 44m€67–110Train to Fiumicino International Airport, fly to Florence Peretola Airport, train
- Take the train from Isernia to Roma Terminitrain
- Fly from Fiumicino International Airport (FCO) to Florence Peretola Airport (FLR)plane FCO - FLR
- Take the train from Firenze S.M.N. to Pisa Centraletrain
6h 58m€96–251Bus, train to Bari Karol Wojtyła Airport, fly to Pisa International Airport
- Take the bus from Isernia to Foggiabus
- Take the train from Foggia to Bari Centraletrain
- Fly from Bari Karol Wojtyła Airport (BRI) to Pisa International Airport (PSA)plane BRI - PSA
6h 24m€66–263Train to Fiumicino International Airport, fly to Bologna Guglielmo Marconi Airport, train
- Take the train from Isernia to Roma Terminitrain
- Fly from Fiumicino International Airport (FCO) to Bologna Guglielmo Marconi Airport (BLQ)plane FCO - BLQ
- Take the train from Bologna Centrale to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Pisa Centraletrain
7h 51m€93–251
Isernia to Pisa by train (Trenitalia)
Comparing Your Travel Options
The cheapest way to get from Isernia to Pisa is to train and bus which costs €35 - €55 and takes 8h 7m.
The fastest way to get from Isernia to Pisa is to drive which takes 5h 4m and costs €80 - €120.
No, there is no direct bus from Isernia to Pisa. However, there are services departing from Isernia and arriving at Pisa via Roma, Autostazione Tiburtina. The journey, including transfers, takes approximately 7h 45m.
No, there is no direct train from Isernia to Pisa. However, there are services departing from Isernia and arriving at Pisa Centrale via Roma Termini. The journey, including transfers, takes approximately 5h 39m.
The distance between Isernia and Pisa is 522 km. The road distance is 507.2 km.
The best way to get from Isernia to Pisa without a car is to train which takes 5h 39m and costs €55 - €110.
It takes approximately 5h 39m to get from Isernia to Pisa, including transfers.
Isernia to Pisa bus services, operated by ATM Azienda di Trasporti Molisana S.p.A., depart from Isernia station.
Isernia to Pisa train services, operated by Trenitalia, depart from Isernia station.
The best way to get from Isernia to Pisa is to train which takes 5h 39m and costs €55 - €110. Alternatively, you can bus, which costs €35 - €70 and takes 7h 45m.
What companies run services between Isernia, Italy and Pisa, Italy?
You can take a train from Isernia to Pisa Centrale via Roma Termini in around 5h 39m. Alternatively, you can take a bus from Isernia to Pisa via Roma, Autostazione Tiburtina in around 7h 45m.
- Website
- ryanair.com
Flights from Naples Airport to Pisa International Airport via Palermo
- Ave. Duration
- 3h 26m
- When
- Thursday, Wednesday, and Saturday
- Estimated price
- €80–240
Flights from Naples Airport to Pisa International Airport via Catania
- Ave. Duration
- 4h 20m
- When
- Friday, Monday, and Saturday
- Estimated price
- €80–240
Flights from Naples Airport to Pisa International Airport via Tirana
- Ave. Duration
- 6h 15m
- When
- Thursday
- Estimated price
- €80–240
Flights from Naples Airport to Pisa International Airport via Cagliari
- Ave. Duration
- 6h 20m
- When
- Saturday
- Estimated price
- €80–240
Flights from Bari Karol Wojtyła Airport to Pisa International Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €30–200
- Website
- ita-airways.com
Flights from Fiumicino International Airport to Florence Peretola Airport
- Ave. Duration
- 55 min
- When
- Every day
- Estimated price
- €60–150
Flights from Fiumicino International Airport to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 5m
- When
- Every day
- Estimated price
- €55–140
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Isernia to Roma Termini
- Ave. Duration
- 2h 24m
- Frequency
- 5 times a day
- Estimated price
- €22–35
- Website
- Trenitalia
Train from Roma Termini to Pisa Centrale
- Ave. Duration
- 4h 18m
- Frequency
- Every 4 hours
- Estimated price
- €40–55
- Website
- Trenitalia
Train from Isernia to Caserta
- Ave. Duration
- 1h 12m
- Frequency
- 5 times a day
- Estimated price
- €10–15
- Website
- Trenitalia
Train from Isernia to Roma Tiburtina
- Ave. Duration
- 2h 26m
- Frequency
- 6 times a week
- Estimated price
- €22–30
- Website
- Trenitalia
Train from Isernia to Cassino
- Ave. Duration
- 46 min
- Frequency
- Every 4 hours
- Estimated price
- €6–9
- Website
- Trenitalia
Train from Isernia to Roma Termini
- Ave. Duration
- 2h 24m
- Frequency
- 5 times a day
- Estimated price
- €22–35
- Website
- Trenitalia
Train from Firenze S.M.N. to Pisa Centrale
- Ave. Duration
- 1h 21m
- Frequency
- Every 30 minutes
- Estimated price
- €9–13
- Website
- Trenitalia
Train from Foggia to Bari Centrale
- Ave. Duration
- 1h 34m
- Frequency
- Hourly
- Estimated price
- €14–20
- Website
- Trenitalia
Train from Isernia to Roma Termini
- Ave. Duration
- 2h 24m
- Frequency
- 5 times a day
- Estimated price
- €22–35
- Website
- Trenitalia
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 51m
- Frequency
- Twice daily
- Estimated price
- €11–15
- Website
- Trenitalia
Train from Firenze S.M.N. to Pisa Centrale
- Ave. Duration
- 1h 21m
- Frequency
- Every 30 minutes
- Estimated price
- €9–13
- Website
- Trenitalia
- Phone
- +39 06 5210550
- Website
- Trenitalia Frecce
Train from Roma Termini to Pisa Centrale
- Ave. Duration
- 2h 27m
- Frequency
- Every 4 hours
- Estimated price
- €45–80
- Website
- Trenitalia Frecce
Train from Roma Tiburtina to Pisa Centrale
- Ave. Duration
- 2h 18m
- Frequency
- Twice daily
- Estimated price
- €45–80
- Website
- Trenitalia Frecce
Train from Foggia to Bari Centrale
- Ave. Duration
- 1h 6m
- Frequency
- Hourly
- Estimated price
- €17–29
- Website
- Trenitalia Frecce
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 37 min
- Frequency
- Every 30 minutes
- Estimated price
- €12–22
- Website
- Trenitalia Frecce
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Roma Termini to Pisa Centrale
- Ave. Duration
- 3h 3m
- Frequency
- Twice daily
- Estimated price
- €35–70
- Website
- Trenitalia Intercity
Train from Foggia to Bari Centrale
- Ave. Duration
- 1h 14m
- Frequency
- Every 4 hours
- Estimated price
- €13–24
- Website
- Trenitalia Intercity
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 16m
- Frequency
- Once daily
- Estimated price
- €9–18
- Website
- Trenitalia Intercity
- Phone
- +39 06 8937 1892
- Website
- Italo Treno
Train from Foggia to Bari Centrale
- Ave. Duration
- 1h 16m
- Frequency
- Once daily
- Estimated price
- €14–24
- Website
- Italo Treno
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 41 min
- Frequency
- 5 times a day
- Estimated price
- €11–18
- Website
- Italo Treno
- Phone
- +39 0874 64744
- [email protected]
- Website
- atm-molise.it
Bus from Isernia to Roma, Autostazione Tiburtina
- Ave. Duration
- 2h 10m
- Frequency
- 3 times a day
- Estimated price
- €8–13
- Schedules at
- atm-molise.it
Rome2Rio's guide to FlixBus
Contact DetailsContact Details
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Isernia to Roma, Autostazione Tiburtina
- Ave. Duration
- 2h 25m
- Frequency
- Once daily
- Estimated price
- €15–23
- Website
- Flixbus
Bus from Roma, Autostazione Tiburtina to Pisa
- Ave. Duration
- 4h 35m
- Frequency
- 3 times a day
- Estimated price
- €29–45
- Website
- Flixbus
Bus from Isernia to Foggia
- Ave. Duration
- 2h 4m
- Frequency
- Once daily
- Estimated price
- €12–19
- Website
- Flixbus
- Phone
- +39 089 233 899
- [email protected]
- Website
- Curcio Viaggi
Bus from Cassino to Pisa
- Ave. Duration
- 6h 15m
- Frequency
- Once daily
- Estimated price
- €30–45
- Website
- Curcio Viaggi
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Booking & Getting There
Isernia to Pisa bus services, operated by ATM Azienda di Trasporti Molisana S.p.A., arrive at Roma, Autostazione Tiburtina station.
Isernia to Pisa train services, operated by Trenitalia, arrive at Roma Termini station.
Yes, the driving distance between Isernia to Pisa is 507 km. It takes approximately 5h 4m to drive from Isernia to Pisa.
Book your Isernia to Pisa train tickets online with Omio.
Book your Isernia to Pisa bus tickets online with Omio and FlixBus.
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