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How to get fromIsernia to Sicilyby train, plane, car, ferry, bus, or train (Trenitalia)

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There are 12 ways to get from Isernia to Sicily by train, plane, car, ferry, bus, or train (Trenitalia)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Naples Airport, fly to Catania–Fontanarossa Airport

    best
    1. Take the train from Isernia to Casertatrain train
    2. Fly from Naples Airport (NAP) to Catania–Fontanarossa Airport (CTA)plane plane NAP - CTA
    4h 55m
    €47–156

  2. Bus via Caserta

    cheapest
    1. Take the bus from Isernia to Caserta Terminal Busbus bus 433
    2. Take the bus from Caserta pzza Garibaldi to Palermo Terminal Busbus bus Autoservizi Salemi S201
    12h 33m
    €39–58

  3. Drive, ferry

    1. Drive from Isernia to Naples Beverellocar car
    2. Take the ferry from Naples Beverello to Port of Palermoferry ferry
    9h 9m
    €48–76

  4. Train, ferry

    1. Take the train from Isernia to Napoli Afragolatrain train Re
    2. Take the train from Napoli Afragola to Villa S.Giovannitrain train Fr
    3. Take the ferry from Villa S.Giovanni to Messina Marittimaferry ferry V1 / ...
    4. Take the train from Messina Centrale to Palermo Centraletrain train Re
    11h 20m

  5. Train to Naples Airport, fly to Palermo Airport

    1. Take the train from Isernia to Casertatrain train
    2. Fly from Naples Airport (NAP) to Palermo Airport (PMO)plane plane NAP - PMO
    5h 17m
    €46–159

  6. Train to Fiumicino International Airport, fly to Catania–Fontanarossa Airport

    1. Take the train from Isernia to Roma Terminitrain train
    2. Fly from Fiumicino International Airport (FCO) to Catania–Fontanarossa Airport (CTA)plane plane FCO - CTA
    5h 33m
    €55–158

  7. Train to Fiumicino International Airport, fly to Palermo Airport

    1. Take the train from Isernia to Roma Terminitrain train
    2. Fly from Fiumicino International Airport (FCO) to Palermo Airport (PMO)plane plane FCO - PMO
    5h 59m
    €51–151

  8. Train to Fiumicino International Airport, fly to Vincenzo Magliocco Airport

    1. Take the train from Isernia to Roma Terminitrain train
    2. Fly from Fiumicino International Airport (FCO) to Vincenzo Magliocco Airport (CIY)plane plane FCO - CIY
    5h 31m
    €87–220

  9. Train to Fiumicino International Airport, fly to Trapani Airport

    1. Take the train from Isernia to Roma Terminitrain train
    2. Fly from Fiumicino International Airport (FCO) to Trapani Airport (TPS)plane plane FCO - TPS
    6h 41m
    €64–197

  10. Bus, train to Abruzzo Airport, fly to Catania–Fontanarossa Airport

    1. Take the bus from Isernia to Montenero Bivio SS16bus bus
    2. Take the train from Montenero-Petacciato to Pescara Porta Nuovatrain train
    3. Fly from Abruzzo Airport (PSR) to Catania–Fontanarossa Airport (CTA)plane plane PSR - CTA
    6h 35m
    €54–149

  11. Train (Trenitalia)

    1. Take the train from Isernia to Napoli Centraletrain train Re
    2. Take the train from Napoli Centrale to Palermo Centraletrain train Ic
    12h 51m
    €87–178

  12. Bus

    1. Take the bus from Isernia to Casello - A1 Ingresso Caianellobus bus 6
    2. Take the bus from Casello - A1 Ingresso Caianello to Palermo Piazza Cairolibus bus
    18h 33m

Naples Airport (NAP) to Catania–Fontanarossa Airport (CTA) flights

Calendar26Weekly Planes
Duration1h 5mAverage Duration
Ticket€26Cheapest Price
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Questions & Answers

Map of how to get from Isernia to Sicily.ExpandLaunch map view
  • Distance: 506.6 km
  • Duration: 4h 55m

What companies run services between Isernia, Italy and Sicily, Italy?

You can take a bus from Isernia to Piazza Boiardo via Caserta Terminal Bus, Caserta pzza Garibaldi, Palermo Terminal Bus, and Stazione Centrale Pensilina Esterna in around 12h 33m. Alternatively, you can take a train from Isernia to Palermo Notarbartolo via Napoli Centrale and Palermo Centrale in around 12h 51m.

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