There are 3 ways to get from Isernia to Spoleto by train (Trenitalia), bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train (Trenitalia)
best- Take the train from Isernia to Roma Terminitrain Re
- Take the train from Roma Termini to Spoletotrain 4150 / ...
4h 34m€36–78Bus
cheapest- Take the bus from Isernia to Roma, Autostazione Tiburtinabus Campobasso / ...
- Take the bus from Roma, Autostazione Tiburtina to Terni Bus Terminalbus E433
5h 51m€19–43Drive 243 km
- Drive from Isernia to Spoletocar 243 km
3h 36m€38–55
Isernia to Spoleto by train (Trenitalia)
Questions & Answers
The cheapest way to get from Isernia to Spoleto is to bus which costs €18 - €45 and takes 5h 51m.
The fastest way to get from Isernia to Spoleto is to drive which takes 3h 36m and costs €35 - €55.
No, there is no direct bus from Isernia to Spoleto. However, there are services departing from Isernia and arriving at Terni Bus Terminal via Roma, Autostazione Tiburtina. The journey, including transfers, takes approximately 5h 51m.
No, there is no direct train from Isernia to Spoleto. However, there are services departing from Isernia and arriving at Spoleto via Roma Termini. The journey, including transfers, takes approximately 4h 34m.
The distance between Isernia and Spoleto is 310 km. The road distance is 243 km.
The best way to get from Isernia to Spoleto without a car is to train which takes 4h 34m and costs €35 - €80.
It takes approximately 4h 34m to get from Isernia to Spoleto, including transfers.
Isernia to Spoleto bus services, operated by ATM Azienda di Trasporti Molisana S.p.A., depart from Isernia station.
Isernia to Spoleto train services, operated by Trenitalia, depart from Isernia station.
The best way to get from Isernia to Spoleto is to train which takes 4h 34m and costs €35 - €80. Alternatively, you can bus, which costs €18 - €45 and takes 5h 51m.
What companies run services between Isernia, Italy and Spoleto, Italy?
You can take a train from Isernia to Spoleto via Roma Termini in around 4h 34m. Alternatively, you can take a bus from Isernia to Spoleto via Roma, Autostazione Tiburtina, Terni Bus Terminal, and Terni in around 5h 51m.
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Isernia to Roma Termini
- Ave. Duration
- 2h 24m
- Frequency
- 5 times a day
- Estimated price
- €23–40
- Website
- Trenitalia
Train from Roma Termini to Spoleto
- Ave. Duration
- 1h 29m
- Frequency
- Hourly
- Estimated price
- €15–25
- Website
- Trenitalia
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Roma Termini to Spoleto
- Ave. Duration
- 1h 41m
- Frequency
- 3 times a day
- Estimated price
- €13–28
- Website
- Trenitalia Intercity
- Phone
- +39 06 68475475
- Website
- Trenitalia Frecce
Train from Roma Termini to Spoleto
- Ave. Duration
- 1h 26m
- Frequency
- Once daily
- Estimated price
- €18–40
- Schedules at
- Trenitalia Frecce
- Phone
- +39 0874 64744
- [email protected]
- Website
- atm-molise.it
Bus from Isernia to Roma, Autostazione Tiburtina
- Ave. Duration
- 2h 10m
- Frequency
- 3 times a day
- Estimated price
- €8–13
- Schedules at
- atm-molise.it
Rome2Rio's guide to FlixBus
Contact DetailsContact Details
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Isernia to Roma, Autostazione Tiburtina
- Ave. Duration
- 2h 25m
- Frequency
- Once daily
- Estimated price
- €13–22
- Website
- Flixbus
Bus from Roma, Autostazione Tiburtina to Terni Bus Terminal
- Ave. Duration
- 1h 25m
- Frequency
- Once daily
- Estimated price
- €7–13
- Website
- Flixbus
- Phone
- +39 06 44101
- [email protected]
- Website
- fsbusitalia.it
Bus from Roma, Autostazione Tiburtina to Terni Bus Terminal
- Ave. Duration
- 1h 35m
- Frequency
- Twice daily
- Estimated price
- €9–12
- Schedules at
- Busitalia Umbria
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More Questions & Answers
Isernia to Spoleto bus services, operated by ATM Azienda di Trasporti Molisana S.p.A., arrive at Roma, Autostazione Tiburtina station.
Isernia to Spoleto train services, operated by Trenitalia, arrive at Roma Termini station.
Yes, the driving distance between Isernia to Spoleto is 243 km. It takes approximately 3h 36m to drive from Isernia to Spoleto.
Book your Isernia to Spoleto train tickets online with Omio.
Book your Isernia to Spoleto bus tickets online with Omio.
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