There are 4 ways to get from Isla Mujeres to Florida Keys by ferry, plane, shuttle, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Ferry to Cancún International Airport, fly to Key West International Airport
best- Take the ferry from Isla Mujeres to Playa Tortugasferry
- Fly from Cancún International Airport (CUN) to Key West International Airport (EYW)plane CUN - EYW
11h 16m$167–467Ferry to Cancún International Airport, fly to Miami International Airport, shuttle
- Take the ferry from Isla Mujeres to Playa Tortugasferry
- Fly from Cancún International Airport (CUN) to Miami International Airport (MIA)plane CUN - MIA
- Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FL
10h 42m$357–617Ferry to Cancún International Airport, fly to Fort Lauderdale–Hollywood International Airport, shuttle
- Take the ferry from Isla Mujeres to Playa Tortugasferry
- Fly from Cancún International Airport (CUN) to Fort Lauderdale–Hollywood International Airport (FLL)plane CUN - FLL
- Take a shuttle bus from Fort Lauderdale, FL - International Airport to Big Pine Key, FL
11h 14m$497–977Ferry, bus, ferry to Cozumel International Airport, fly to Key West International Airport
- Take the ferry from Isla Mujeres to Playa Tortugasferry
- Take the bus from Terminal de Autobuses ADO Cancún to Playa del Carmen Terminal Turísticabus
- Take the ferry from Playa del Carmen to Cozumelferry
- Fly from Cozumel International Airport (CZM) to Key West International Airport (EYW)plane CZM - EYW
27h 48m$198–637
Cancún International Airport (CUN) to Key West International Airport (EYW) flights
Questions & Answers
The cheapest way to get from Isla Mujeres to Florida Keys is to ferry and fly which costs $160 - $470 and takes 11h 16m.
The fastest way to get from Isla Mujeres to Florida Keys is to ferry and fly and shuttle which takes 10h 42m and costs $350 - $650.
The distance between Isla Mujeres and Florida Keys is 465 miles.
It takes approximately 11h 16m to get from Isla Mujeres to Florida Keys, including transfers.
There are 971+ hotels available in Florida Keys.
What companies run services between Isla Mujeres, Mexico and Florida Keys, FL, USA?
There is no direct connection from Isla Mujeres to Florida Keys. However, you can take the ferry to Playa Tortugas, walk to Playa Tortugas, take the shuttle to Aeropuerto Internacional de Cancún Terminal 2, walk to Cancún International Airport (CUN) airport, fly to Key West International Airport (EYW), walk to Key West Airport, take the shuttle to Key West, FL, walk to Whitehead & Eaton, take the bus to Sugarloaf Key - Lower - Opposite Sugarloaf Lodge, then walk to Florida Keys. Alternatively, you can take the ferry to Playa Tortugas, walk to Playa Tortugas, take the shuttle to Aeropuerto Internacional de Cancún Terminal 2, walk to Cancún International Airport (CUN) airport, fly to Miami International Airport (MIA), walk to Miami, FL - International Airport, take the shuttle to Big Pine Key, FL, walk to Big Pine Key - CVS / MM30, take the bus to Sugarloaf Key - Lower - Sugarloaf Lodge, then walk to Florida Keys.
- Website
- aa.com
Flights from Cancún International Airport to Key West International Airport via Miami International Airport
- Ave. Duration
- 5h 12m
- When
- Every day
- Estimated price
- $55–300
Flights from Cancún International Airport to Miami International Airport
- Ave. Duration
- 1h 56m
- When
- Every day
- Estimated price
- $60–330
Flights from Cozumel International Airport to Key West International Airport via Miami International Airport
- Ave. Duration
- 18h 46m
- When
- Tuesday to Sunday
- Estimated price
- $90–460
Flights from Cozumel International Airport to Key West International Airport via Charlotte
- Ave. Duration
- 23h 22m
- When
- Saturday
- Estimated price
- $180–750
Flights from Cozumel International Airport to Key West International Airport via Chicago O'Hare
- Ave. Duration
- 24h 28m
- When
- Saturday
- Estimated price
- $260–1,000
Flights from Cozumel International Airport to Key West International Airport via Dallas/Ft.Worth
- Ave. Duration
- 25h 9m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $210–850
- Website
- delta.com
Flights from Cancún International Airport to Key West International Airport via Atlanta
- Ave. Duration
- 8h 21m
- When
- Every day
- Estimated price
- $100–450
Flights from Cancún International Airport to Miami International Airport
- Ave. Duration
- 1h 55m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $60–330
Flights from Cozumel International Airport to Key West International Airport via Atlanta
- Ave. Duration
- 19h 30m
- When
- Every day
- Estimated price
- $160–700
- Website
- aeromexico.com
Flights from Cancún International Airport to Key West International Airport via Atlanta
- Ave. Duration
- 8h 21m
- When
- Every day
- Estimated price
- $100–450
Flights from Cancún International Airport to Miami International Airport
- Ave. Duration
- 1h 55m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $60–330
- Website
- jetblue.com
Flights from Cancún International Airport to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 1h 47m
- When
- Every day
- Estimated price
- $60–350
- Website
- flybreeze.com
Flights from Cancún International Airport to Key West International Airport via Tampa
- Ave. Duration
- 5h 8m
- When
- Thursday and Sunday
- Estimated price
- $65–320
- Website
- latam.com
Flights from Cancún International Airport to Miami International Airport
- Ave. Duration
- 1h 45m
- When
- Sunday
- Estimated price
- $120–550
- Website
- united.com
Flights from Cozumel International Airport to Key West International Airport via Chicago O'Hare
- Ave. Duration
- 25h 11m
- When
- Saturday
- Estimated price
- $260–1,000
- Phone
- +1 (305) 289-9997
- [email protected]
- Website
- keysshuttle.com
Shuttle from Miami, FL - International Airport to Big Pine Key, FL
- Ave. Duration
- 3h
- Frequency
- 3 times a day
- Estimated price
- $150–180
- Website
- https://www.keysshuttle.com
Shuttle from Fort Lauderdale, FL - International Airport to Big Pine Key, FL
- Ave. Duration
- 3h 30m
- Frequency
- 3 times a day
- Estimated price
- $170–200
- Website
- https://www.keysshuttle.com
- Phone
- +52 55 4386 4652
- [email protected]
- Website
- ado.com.mx
Bus from Terminal de Autobuses ADO Cancún to Playa del Carmen Terminal Turística
- Ave. Duration
- 1h 20m
- Frequency
- Every 30 minutes
- Estimated price
- $11–17
- Schedules at
- ado.com.mx
- Book at
- ado.com.mx
- Phone
- +52 997 976 0191
- [email protected]
- Website
- ado.com.mx
Bus from Terminal de Autobuses ADO Cancún to Playa del Carmen Terminal Turística
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- $4–6
- Schedules at
- ahorrobus.com.mx
- Phone
- +52 998 460 3084
- [email protected]
- Website
- ultramarferry.com
Ferry from Isla Mujeres to Playa Tortugas
- Ave. Duration
- 30 min
- Frequency
- Every 3 hours
- Estimated price
- $13–18
- Website
- https://www.ultramarferry.com/en
- Premium Plus
- $16–18
- Adult
- $17
- Child
- $13
Ferry from Isla Mujeres to Playa Tortugas
- Ave. Duration
- 30 min
- Frequency
- Every 3 hours
- Estimated price
- $13–18
- Website
- https://www.ultramarferry.com/en
- Premium Plus
- $16–18
- Adult
- $17
- Child
- $13
Ferry from Isla Mujeres to Playa Tortugas
- Ave. Duration
- 30 min
- Frequency
- Every 3 hours
- Estimated price
- $13–18
- Website
- https://www.ultramarferry.com/en
- Premium Plus
- $16–18
- Adult
- $17
- Child
- $13
Ferry from Isla Mujeres to Playa Tortugas
- Ave. Duration
- 30 min
- Frequency
- Every 3 hours
- Estimated price
- $13–18
- Website
- https://www.ultramarferry.com/en
- Premium Plus
- $16–18
- Adult
- $17
- Child
- $13
Ferry from Playa del Carmen to Cozumel
- Ave. Duration
- 40 min
- Frequency
- Every 3 hours
- Estimated price
- $6–22
- Website
- https://www.ultramarferry.com/en
- Premium Plus
- $17–19
- Premium Plus Adult
- $19
- Premium Plus Children
- $14
- Residentes Q.Roo
- $11
- INAPAM
- $6
- First Class Adult
- $22
- First Class Children
- $22
- Phone
- +52 987 872 1588
- [email protected]
- Website
- winjet.mx
Ferry from Playa del Carmen to Cozumel
- Ave. Duration
- 45 min
- Frequency
- Every 3 hours
- Estimated price
- $7–20
- Schedules at
- winjet.mx
- General
- $20
- Handicapped
- $7
- Minor
- $16
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