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How to get fromIsla Mujeres to Florida Keysby ferry, plane, shuttle, or bus

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There are 4 ways to get from Isla Mujeres to Florida Keys by ferry, plane, shuttle, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Ferry to Cancún International Airport, fly to Key West International Airport

    best
    1. Take the ferry from Isla Mujeres to Playa Tortugasferry ferry
    2. Fly from Cancún International Airport (CUN) to Key West International Airport (EYW)plane plane CUN - EYW
    10h 48m
    $170–516

  2. Ferry to Cancún International Airport, fly to Miami International Airport, shuttle

    1. Take the ferry from Isla Mujeres to Playa Tortugasferry ferry
    2. Fly from Cancún International Airport (CUN) to Miami International Airport (MIA)plane plane CUN - MIA
    3. Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FLshuttle bus
    10h 44m
    $375–726

  3. Ferry to Cancún International Airport, fly to Fort Lauderdale–Hollywood International Airport, shuttle

    1. Take the ferry from Isla Mujeres to Playa Tortugasferry ferry
    2. Fly from Cancún International Airport (CUN) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane CUN - FLL
    3. Take a shuttle bus from Fort Lauderdale, FL - International Airport to Big Pine Key, FLshuttle bus
    11h 13m
    $275–686

  4. Ferry, bus, ferry to Cozumel International Airport, fly to Key West International Airport

    1. Take the ferry from Isla Mujeres to Playa Tortugasferry ferry
    2. Take the bus from Terminal de Autobuses ADO Cancún to Playa del Carmen Terminal Turísticabus bus
    3. Take the ferry from Playa del Carmen to Cozumelferry ferry
    4. Fly from Cozumel International Airport (CZM) to Key West International Airport (EYW)plane plane CZM - EYW
    13h
    $192–652

Cancún International Airport (CUN) to Key West International Airport (EYW) flights

Calendar31Weekly Planes
Duration6h 28mAverage Duration
Ticket$63Cheapest Price
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Comparing Your Travel Options

Map of how to get from Isla Mujeres to Florida Keys.ExpandLaunch map view
  • Distance: 462.6 mi
  • Duration: 10h 48m

What companies run services between Isla Mujeres, Mexico and Florida Keys, FL, USA?

There is no direct connection from Isla Mujeres to Florida Keys. However, you can take the ferry to Playa Tortugas, walk to Playa Tortugas, take the shuttle to Aeropuerto Internacional de Cancún Terminal 2, walk to Cancún International Airport (CUN) airport, fly to Key West International Airport (EYW), walk to Key West Airport, take the shuttle to Key West, FL, walk to Whitehead & Eaton, take the bus to Sugarloaf Key - Lower - Opposite Sugarloaf Lodge, then walk to Florida Keys. Alternatively, you can take the ferry to Playa Tortugas, walk to Playa Tortugas, take the shuttle to Aeropuerto Internacional de Cancún Terminal 2, walk to Cancún International Airport (CUN) airport, fly to Miami International Airport (MIA), walk to Miami, FL - International Airport, take the shuttle to Big Pine Key, FL, walk to Big Pine Key - CVS / MM30, take the bus to Sugarloaf Key - Lower - Sugarloaf Lodge, then walk to Florida Keys.

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