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How to get fromIsle of Palms to Destinby plane, bus, taxi, car, or train

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There are 6 ways to get from Isle of Palms to Destin by plane, bus, taxi, car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Destin–Fort Walton Beach Airport

    best
    1. Fly from Charleston International Airport (CHS) to Destin–Fort Walton Beach Airport (VPS)plane plane CHS - VPS
    4h 6m
    $190–511

  2. Drive 496.7 mi

    cheapest
    1. Drive from Isle of Palms to Destincar car 496.7 mi
    10h 7m
    $91–131

  3. Bus, taxi

    1. Take the bus from Charleston Bus Station to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta to Mobilebus bus
    3. Take the bus from Loxley to Crestviewbus bus
    4. Take the taxi from Crestview to Destintaxi taxi
    21h 35m
    $331–473

  4. Fly to Northwest Florida Beaches International Airport, taxi

    1. Fly from Charleston International Airport (CHS) to Northwest Florida Beaches International Airport (ECP)plane plane CHS - ECP
    2. Take the taxi from Northwest Florida Beaches International Airport (ECP) to Destintaxi taxi
    4h 53m
    $290–636

  5. Fly to Pensacola International Airport, taxi

    1. Fly from Charleston International Airport (CHS) to Pensacola International Airport (PNS)plane plane CHS - PNS
    2. Take the taxi from Pensacola-Airport-PNS to Destintaxi taxi
    4h 58m
    $570–1,466

  6. Train, bus, taxi

    1. Take the train from Charleston Amtrak Station to Jacksonvilletrain train
    2. Take the bus from Jacksonville to Mobile Bus Stationbus bus
    3. Take the bus from Mobile to Crestviewbus bus
    4. Take the taxi from Crestview to Destintaxi taxi
    23h 17m
    $324–543

Charleston International Airport (CHS) to Destin–Fort Walton Beach Airport (VPS) flights

Calendar67Weekly Planes
Duration4h 23mAverage Duration
Ticket$62Cheapest Price
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Questions & Answers

Map of how to get from Isle of Palms to Destin.ExpandLaunch map view
  • Distance: 453.7 mi
  • Duration: 4h 6m

What companies run services between Isle of Palms, SC, USA and Destin, FL, USA?

Delta, American Airlines, and Southwest Airlines fly from Charleston International Airport (CHS) to Destin–Fort Walton Beach Airport (VPS) every 3 hours.

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