Rome2Rio

How to get fromIslip to Knoxvilleby train, plane, bus, or car

Find Transport to Knoxville

See all options

There are 9 ways to get from Islip to Knoxville by train, plane, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Newark Liberty International Airport, fly to Mcghee Tyson Airport

    best
    1. Take the train from Islip to Jamaicatrain train
    2. Fly from Newark Liberty International Airport (EWR) to Mcghee Tyson Airport (TYS)plane plane EWR - TYS
    5h 1m
    $269–1,126

  2. Train to Laguardia Airport, fly to Asheville Regional Airport, drive

    cheapest
    1. Take the train from Islip to Jamaicatrain train
    2. Fly from Laguardia Airport (LGA) to Asheville Regional Airport (AVL)plane plane LGA - AVL
    3. Drive from Asheville-Airport-AVL to Knoxvillecar car
    6h 43m
    $125–609

  3. Train, bus

    1. Take the train from Islip to Jamaicatrain train Montauk Branch
    2. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    14h 56m
    $148–184

  4. Drive  746.8 mi

    1. Drive from Islip to Knoxvillecar car 746.8 mi
    13h 2m
    $137–197

  5. Train to Laguardia Airport, fly to Mcghee Tyson Airport

    1. Take the train from Islip to Jamaicatrain train
    2. Fly from Laguardia Airport (LGA) to Mcghee Tyson Airport (TYS)plane plane LGA - TYS
    4h 59m
    $298–1,394

  6. Fly Long Island Mac Arthur Airport to Mcghee Tyson Airport

    1. Fly from Long Island Mac Arthur Airport (ISP) to Mcghee Tyson Airport (TYS)plane plane ISP - TYS
    6h 21m
    $290–1,375

  7. Train, train to Philadelphia International Airport, fly to Mcghee Tyson Airport

    1. Take the train from Islip to Jamaicatrain train
    2. Take the train from Ny Moynihan Train Hall At Penn Station to 30th Street Stationtrain train
    3. Fly from Philadelphia International Airport (PHL) to Mcghee Tyson Airport (TYS)plane plane PHL - TYS
    6h 45m
    $289–1,901

  8. Train to Newark Liberty International Airport, fly to Asheville Regional Airport, drive

    1. Take the train from Islip to Jamaicatrain train
    2. Fly from Newark Liberty International Airport (EWR) to Asheville Regional Airport (AVL)plane plane EWR - AVL
    3. Drive from Asheville-Airport-AVL to Knoxvillecar car
    7h 3m
    $126–501

  9. Train, bus via Farragut

    1. Take the train from Babylon to Jamaicatrain train Babylon Branch / ...
    2. Take the bus from New York to Knoxvillebus bus Nyc
    15h 29m
    $193–273

Newark Liberty International Airport (EWR) to Mcghee Tyson Airport (TYS) flights

Calendar85Weekly Planes
Duration3h 33mAverage Duration
Ticket$182Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Islip to Knoxville.ExpandLaunch map view
  • Distance: 701.2 mi
  • Duration: 5h 1m

What companies run services between Islip, NY, USA and Knoxville, TN, USA?

Southwest Airlines, Cape Air, and Allegiant Air fly from Long Island Mac Arthur Airport (ISP) to Mcghee Tyson Airport (TYS) once daily.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides