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How to get fromIslip to Knoxvilleby train, plane, bus, or car

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There are 8 ways to get from Islip to Knoxville by train, plane, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Laguardia Airport, fly to Mcghee Tyson Airport

    best
    1. Take the train from Islip to Jamaicatrain train
    2. Fly from Laguardia Airport (LGA) to Mcghee Tyson Airport (TYS)plane plane LGA - TYS
    5h 2m
    $308–1,494

  2. Train to Laguardia Airport, fly to Asheville Regional Airport, drive

    cheapest
    1. Take the train from Islip to Jamaicatrain train
    2. Fly from Laguardia Airport (LGA) to Asheville Regional Airport (AVL)plane plane LGA - AVL
    3. Drive from Asheville-Airport-AVL to Knoxvillecar car
    6h 53m
    $118–534

  3. Train, bus

    1. Take the train from Islip to Jamaicatrain train Montauk Branch
    2. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    14h 59m
    $148–184

  4. Drive  746.8 mi

    1. Drive from Islip to Knoxvillecar car 746.8 mi
    13h 2m
    $128–185

  5. Train to Newark Liberty International Airport, fly to Mcghee Tyson Airport

    1. Take the train from Islip to Jamaicatrain train
    2. Fly from Newark Liberty International Airport (EWR) to Mcghee Tyson Airport (TYS)plane plane EWR - TYS
    5h 15m
    $279–1,226

  6. Fly Long Island Mac Arthur Airport to Mcghee Tyson Airport

    1. Fly from Long Island Mac Arthur Airport (ISP) to Mcghee Tyson Airport (TYS)plane plane ISP - TYS
    6h 56m
    $350–1,675

  7. Train, train to Philadelphia International Airport, fly to Mcghee Tyson Airport

    1. Take the train from Islip to Jamaicatrain train
    2. Take the train from Ny Moynihan Train Hall At Penn Station to 30th Street Stationtrain train
    3. Fly from Philadelphia International Airport (PHL) to Mcghee Tyson Airport (TYS)plane plane PHL - TYS
    6h 46m
    $379–2,401

  8. Train to Newark Liberty International Airport, fly to Asheville Regional Airport, drive

    1. Take the train from Islip to Jamaicatrain train
    2. Fly from Newark Liberty International Airport (EWR) to Asheville Regional Airport (AVL)plane plane EWR - AVL
    3. Drive from Asheville-Airport-AVL to Knoxvillecar car
    7h 4m
    $119–476

Laguardia Airport (LGA) to Mcghee Tyson Airport (TYS) flights

Calendar84Weekly Planes
Duration3h 43mAverage Duration
Ticket$240Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Islip to Knoxville.ExpandLaunch map view
  • Distance: 701.6 mi
  • Duration: 5h 2m

What companies run services between Islip, NY, USA and Knoxville, TN, USA?

Southwest Airlines, Cape Air, and Allegiant Air fly from Long Island Mac Arthur Airport (ISP) to Mcghee Tyson Airport (TYS) once daily.

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