Rome2Rio

How to get fromIslip to St. Louisby train, plane, bus, train (Amtrak), or car

Find Transport to St. Louis

See all options

There are 8 ways to get from Islip to St. Louis by train, plane, bus, train (Amtrak), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Laguardia Airport, fly

    best
    1. Take the train from Islip to Jamaicatrain train
    2. Fly from Laguardia Airport (LGA) to Lambert–St. Louis International Airport (STL)plane plane LGA - STL
    5h 49m
    $196–577

  2. Train to John F. Kennedy International Airport, fly

    cheapest
    1. Take the train from Islip to Jamaicatrain train
    2. Fly from John F. Kennedy International Airport (JFK) to Lambert–St. Louis International Airport (STL)plane plane JFK - STL
    7h 23m
    $122–583

  3. Train, bus

    1. Take the train from Babylon to New York Penn Stationtrain train Babylon Branch / ...
    2. Take the bus from Port Authority Bus Terminal to St Louis Bus Stationbus bus Greyhound US0421
    25h 31m
    $193–306

  4. Train

    1. Take the train from Babylon to New York Penn Stationtrain train
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to St. Louistrain train
    28h 10m
    $663–1,116

  5. Drive  987.4 mi

    1. Drive from Islip to St. Louiscar car 987.4 mi
    17h 28m
    $181–261

  6. Fly from Long Island Mac Arthur Airport

    1. Fly from Long Island Mac Arthur Airport (ISP) to Lambert–St. Louis International Airport (STL)plane plane ISP - STL
    7h 37m
    $168–858

  7. Train to Newark Liberty International Airport, fly

    1. Take the train from Islip to Jamaicatrain train
    2. Fly from Newark Liberty International Airport (EWR) to Lambert–St. Louis International Airport (STL)plane plane EWR - STL
    6h 29m
    $327–959

  8. Train, train to Philadelphia International Airport, fly

    1. Take the train from Islip to Jamaicatrain train
    2. Take the train from Ny Moynihan Train Hall At Penn Station to 30th Street Stationtrain train
    3. Fly from Philadelphia International Airport (PHL) to Lambert–St. Louis International Airport (STL)plane plane PHL - STL
    7h 30m
    $157–1,384

Islip to St. Louis by bus, train, and foot

Calendar21Weekly Services
Duration25h 31mAverage Duration
Ticket$193Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Islip to St. Louis.ExpandLaunch map view
  • Distance: 942 mi
  • Duration: 5h 49m

What companies run services between Islip, NY, USA and St. Louis, MO, USA?

You can take a bus from Islip Town Hall to St. Louis via Babylon LIRR, Babylon, Penn Station, Ny Moynihan Train Hall At Penn Station, and Chicago Union Station in around 28h 10m. Alternatively, Southwest Airlines flies from Long Island Mac Arthur Airport (ISP) to Lambert–St. Louis International Airport (STL) 4 times a day.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Booking & Getting There