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How to get fromIspra to Karlsruheby train (Trenitalia), bus, car, train, plane, or night train

Find Transport to Karlsruhe

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There are 10 ways to get from Ispra to Karlsruhe by train (Trenitalia), bus, car, train, plane, or night train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Trenitalia)

    best
    1. Take the train from Lugano to Karlsruhe Hbftrain train Ec
    8h 1m
    €102–159

  2. Bus

    cheapest
    1. Take the bus from Como Grandate to Karlsruhe central train stationbus bus FlixBus 024
    12h 46m
    €51–78

  3. Drive  490.5 km

    1. Drive from Ispra to Karlsruhecar car 490.5 km
    5h 9m
    €92–133

  4. Train to Milan Linate Airport, fly to Stuttgart Airport, train

    1. Take the train from Gavirate to Milano Cadornatrain train
    2. Fly from Milan Linate Airport (LIN) to Stuttgart Airport (STR)plane plane LIN - STR
    3. Take the train from Hauptbahnhof to Karlsruhe Hauptbahnhoftrain train
    6h 56m
    €127–404

  5. Train via Basel

    1. Take the train from Lugano to Basel SBBtrain train Ic21 / ...
    2. Take the train from Basel SBB to Karlsruhe Hauptbahnhoftrain train 12 / ...
    8h 1m
    €57–329

  6. Train, night train

    1. Take the train from Varese to Castionetrain train S50
    2. Take the train from Castione-Arbedo to Zürich HBtrain train
    3. Take the nighttrain from Zuerich Hb to Karlsruhe Hbfnighttrain night train Nj
    10h 46m
    €88–191

  7. Train to Milano Malpensa Airport, fly to Frankfurt, train

    1. Take the train from Varese to Malpensa Aeroporto T1train train
    2. Fly from Milano Malpensa Airport (MXP) to Frankfurt (FRA)plane plane MXP - FRA
    3. Take the train from Frankfurt to Karlsruhe Hauptbahnhoftrain train
    7h 7m
    €82–250

  8. Train to Zurich Airport, fly to Stuttgart Airport, train

    1. Take the train from Lugano to Zürich HBtrain train
    2. Fly from Zurich Airport (ZRH) to Stuttgart Airport (STR)plane plane ZRH - STR
    3. Take the train from Hauptbahnhof to Karlsruhe Hauptbahnhoftrain train
    8h 4m
    €192–517

  9. Train to Milan Linate Airport, fly to Frankfurt, train

    1. Take the train from Gavirate to Milano Cadornatrain train
    2. Fly from Milan Linate Airport (LIN) to Frankfurt (FRA)plane plane LIN - FRA
    3. Take the train from Frankfurt to Karlsruhe Hauptbahnhoftrain train
    7h 40m
    €54–210

  10. Train to Milano Malpensa Airport, fly to Zurich Airport, train

    1. Take the train from Varese to Malpensa Aeroporto T1train train
    2. Fly from Milano Malpensa Airport (MXP) to Zurich Airport (ZRH)plane plane MXP - ZRH
    3. Take the train from Zürich HB to Basel SBBtrain train
    4. Take the train from Basel SBB to Karlsruhe Hauptbahnhoftrain train
    8h 26m
    €140–459

Ispra to Karlsruhe by bus and train (Trenitalia)

Calendar7Weekly Services
Duration8h 1mAverage Duration
Ticket€102Cheapest Price
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Comparing Your Travel Options

Map of how to get from Ispra to Karlsruhe.ExpandLaunch map view
  • Distance: 520.4 km
  • Duration: 8h 1m

What companies run services between Ispra, Italy and Karlsruhe, Germany?

Trenitalia EuroCity operates a train from Lugano to Karlsruhe Hbf once daily. Tickets cost €95–150 and the journey takes 4h 56m. Alternatively, FlixBus operates a bus from Como Grandate to Karlsruhe central train station 5 times a week. Tickets cost €45–70 and the journey takes 9h 5m.

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