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How to get fromIspra to Karlsruheby train (Trenitalia), bus, car, train, plane, or night train

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There are 11 ways to get from Ispra to Karlsruhe by train (Trenitalia), bus, car, train, plane, or night train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Stresa to Basel Sbbtrain train Ec
    2. Take the train from Basel SBB to Karlsruhe Hauptbahnhoftrain train 12 / ...
    6h 17m
    €163–341

  2. Bus

    cheapest
    1. Take the bus from Como Grandate to Karlsruhe central train stationbus bus FlixBus 024
    12h 26m
    €48–83

  3. Drive 490.5 km

    1. Drive from Ispra to Karlsruhecar car 490.5 km
    5h 9m
    €77–112

  4. Train to Milano Malpensa Airport, fly to Stuttgart Airport, train

    1. Take the train from Varese to Malpensa Aeroporto T1train train
    2. Fly from Milano Malpensa Airport (MXP) to Stuttgart Airport (STR)plane plane MXP - STR
    3. Take the train from Stuttgart Hbf to Karlsruhe Hbftrain train
    6h 21m
    €87–278

  5. Train via Lugano

    1. Take the train from Lugano to Basel SBBtrain train Ic21 / ...
    2. Take the train from Basel SBB to Karlsruhe Hauptbahnhoftrain train 12 / ...
    7h 57m
    €59–435

  6. Train #2 (Trenitalia)

    1. Take the train from Lugano to Karlsruhe Hbftrain train Ec
    8h 4m
    €99–155

  7. Train, night train

    1. Take the train from Varese to Castionetrain train S50
    2. Take the train from Castione-Arbedo to Zürich HBtrain train
    3. Take the night train from Zuerich Hb to Karlsruhe Hbfnighttrain night train Nj
    10h 49m
    €84–186

  8. Train to Milano Malpensa Airport, fly to Frankfurt, train

    1. Take the train from Varese to Malpensa Aeroporto T1train train
    2. Fly from Milano Malpensa Airport (MXP) to Frankfurt (FRA)plane plane MXP - FRA
    3. Take the train from Frankfurt to Karlsruhe Hauptbahnhoftrain train
    7h 2m
    €78–335

  9. Train to Milano Malpensa Airport, fly to Zurich Airport, train

    1. Take the train from Varese to Malpensa Aeroporto T1train train
    2. Fly from Milano Malpensa Airport (MXP) to Zurich Airport (ZRH)plane plane MXP - ZRH
    3. Take the train from Zürich HB to Basel SBBtrain train
    4. Take the train from Basel SBB to Karlsruhe Hauptbahnhoftrain train
    7h 26m
    €142–477

  10. Train to Zurich Airport, fly to Stuttgart Airport, train

    1. Take the train from Lugano to Zuerich Hbtrain train
    2. Fly from Zurich Airport (ZRH) to Stuttgart Airport (STR)plane plane ZRH - STR
    3. Take the train from Stuttgart Hbf to Karlsruhe Hbftrain train
    8h 6m
    €165–460

  11. Train to Milan Linate Airport, fly to Frankfurt, train

    1. Take the train from Varese to Milano Dateotrain train
    2. Fly from Milan Linate Airport (LIN) to Frankfurt (FRA)plane plane LIN - FRA
    3. Take the train from Frankfurt to Karlsruhe Hauptbahnhoftrain train
    8h 4m
    €60–258

Ispra to Karlsruhe by bus and train

Calendar101Weekly Services
Duration7h 57mAverage Duration
Ticket€59Cheapest Price
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Questions & Answers

Map of how to get from Ispra to Karlsruhe.ExpandLaunch map view
  • Distance: 512 km
  • Duration: 6h 17m

What companies run services between Ispra, Italy and Karlsruhe, Germany?

You can take a vehicle from Ispra to Karlsruhe Hauptbahnhof via Stresa and Basel SBB in around 6h 17m. Alternatively, FlixBus operates a bus from Como Grandate to Karlsruhe central train station 6 times a week. Tickets cost €45–80 and the journey takes 8h 45m.

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