Rome2Rio

How to get fromIspra to Karlsruheby train (Trenitalia), bus, car, train, plane, or night train

Find Transport to Karlsruhe

See all options

There are 10 ways to get from Ispra to Karlsruhe by train (Trenitalia), bus, car, train, plane, or night train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train via Basel

    best
    1. Take the train from Lugano to Basel SBBtrain train Ic21 / ...
    2. Take the train from Basel SBB to Karlsruhe Hauptbahnhoftrain train 12 / ...
    8h
    €62–209

  2. Bus

    cheapest
    1. Take the bus from Como Grandate to Karlsruhe central train stationbus bus FlixBus 024
    12h 46m
    €46–73

  3. Drive  490.5 km

    1. Drive from Ispra to Karlsruhecar car 490.5 km
    5h 9m
    €79–114

  4. Train to Milano Malpensa Airport, fly to Stuttgart Airport, train

    1. Take the train from Varese to Malpensa Aeroporto T1train train
    2. Fly from Milano Malpensa Airport (MXP) to Stuttgart Airport (STR)plane plane MXP - STR
    3. Take the train from Hauptbahnhof to Karlsruhe Hauptbahnhoftrain train
    6h 20m
    €80–235

  5. Train (Trenitalia)

    1. Take the train from Lugano to Karlsruhe Hbftrain train Ec
    8h 4m
    €102–159

  6. Train, night train

    1. Take the train from Varese to Castionetrain train S50
    2. Take the train from Castione-Arbedo to Zürich HBtrain train
    3. Take the nighttrain from Zuerich Hb to Karlsruhe Hbfnighttrain night train Nj
    10h 49m
    €88–191

  7. Train to Milano Malpensa Airport, fly to Frankfurt, train

    1. Take the train from Varese to Malpensa Aeroporto T1train train
    2. Fly from Milano Malpensa Airport (MXP) to Frankfurt (FRA)plane plane MXP - FRA
    3. Take the train from Frankfurt to Karlsruhe Hauptbahnhoftrain train
    7h 2m
    €82–254

  8. Train to Milano Malpensa Airport, fly to Zurich Airport, train

    1. Take the train from Varese to Malpensa Aeroporto T1train train
    2. Fly from Milano Malpensa Airport (MXP) to Zurich Airport (ZRH)plane plane MXP - ZRH
    3. Take the train from Zürich HB to Basel SBBtrain train
    4. Take the train from Basel SBB to Karlsruhe Hauptbahnhoftrain train
    7h 29m
    €145–338

  9. Train to Zurich Airport, fly to Stuttgart Airport, train

    1. Take the train from Lugano to Zuerich Hbtrain train
    2. Fly from Zurich Airport (ZRH) to Stuttgart Airport (STR)plane plane ZRH - STR
    3. Take the train from Hauptbahnhof to Karlsruhe Hauptbahnhoftrain train
    8h 5m
    €157–419

  10. Train to Milan Linate Airport, fly to Frankfurt, train

    1. Take the train from Gavirate to Milano Cadornatrain train
    2. Fly from Milan Linate Airport (LIN) to Frankfurt (FRA)plane plane LIN - FRA
    3. Take the train from Frankfurt to Karlsruhe Hauptbahnhoftrain train
    7h 45m
    €59–205

Ispra to Karlsruhe by bus and train

Calendar102Weekly Services
Duration8hAverage Duration
Ticket€62Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Ispra to Karlsruhe.ExpandLaunch map view
  • Distance: 509.5 km
  • Duration: 8h

What companies run services between Ispra, Italy and Karlsruhe, Germany?

You can take a bus from Ispra, Mazzini/Roma,distributore to Karlsruhe Hauptbahnhof via Varese, Morosini,Stazione FS FN, Varese, Lugano, and Basel SBB in around 8h. Alternatively, FlixBus operates a bus from Como Grandate to Karlsruhe central train station 5 times a week. Tickets cost €40–65 and the journey takes 9h 5m.

Airlines
Train operators
Bus operators

Want to know more about travelling around Germany

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Italy Travel Guides

Read the travel guideItaly Travel Guides

Booking & Getting There