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How to get fromIspra to Karlsruheby train (Trenitalia), bus, car, train, plane, or night train

Find Transport to Karlsruhe

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There are 12 ways to get from Ispra to Karlsruhe by train (Trenitalia), bus, car, train, plane, or night train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Stresa to Basel Sbbtrain train Ec
    2. Take the train from Basel SBB to Karlsruhe Hauptbahnhoftrain train 12 / ...
    6h 11m
    €149–286

  2. Train via Lugano

    cheapest
    1. Take the train from Lugano to Basel SBBtrain train Ic21 / ...
    2. Take the train from Basel SBB to Karlsruhe Hauptbahnhoftrain train 12 / ...
    7h 52m
    €48–234

  3. Bus

    1. Take the bus from Como Grandate to Karlsruhe central train stationbus bus FlixBus 024
    12h 46m
    €51–83

  4. Drive  490.5 km

    1. Drive from Ispra to Karlsruhecar car 490.5 km
    5h 9m
    €92–132

  5. Train to Milan Linate Airport, fly to Stuttgart Airport, train

    1. Take the train from Gavirate to Milano Cadornatrain train
    2. Fly from Milan Linate Airport (LIN) to Stuttgart Airport (STR)plane plane LIN - STR
    3. Take the train from Stuttgart Hbf to Karlsruhe Hbftrain train
    6h 55m
    €121–325

  6. Train #2 (Trenitalia)

    1. Take the train from Lugano to Karlsruhe Hbftrain train Ec
    8h 4m
    €102–159

  7. Train, night train

    1. Take the train from Varese to Castionetrain train S50
    2. Take the train from Castione-Arbedo to Zürich HBtrain train
    3. Take the nighttrain from Zuerich Hb to Karlsruhe Hbfnighttrain night train Nj
    10h 48m
    €88–191

  8. Train to Milano Malpensa Airport, fly to Frankfurt, train

    1. Take the train from Varese to Malpensa Aeroporto T1train train
    2. Fly from Milano Malpensa Airport (MXP) to Frankfurt (FRA)plane plane MXP - FRA
    3. Take the train from Frankfurt to Karlsruhe Hauptbahnhoftrain train
    7h 7m
    €89–250

  9. Train to Zurich Airport, fly to Stuttgart Airport, train

    1. Take the train from Lugano to Zuerich Hbtrain train
    2. Fly from Zurich Airport (ZRH) to Stuttgart Airport (STR)plane plane ZRH - STR
    3. Take the train from Stuttgart Hbf to Karlsruhe Hbftrain train
    8h 7m
    €181–448

  10. Train to Milan Linate Airport, fly to Frankfurt, train

    1. Take the train from Gavirate to Milano Cadornatrain train
    2. Fly from Milan Linate Airport (LIN) to Frankfurt (FRA)plane plane LIN - FRA
    3. Take the train from Frankfurt to Karlsruhe Hauptbahnhoftrain train
    7h 40m
    €66–210

  11. Bus, train to Milano Malpensa Airport, fly to Strasbourg International Airport, train

    1. Take the bus from Ispra, Mazzini/Roma,distributore to Varese, Morosini,Stazione FS FNbus bus
    2. Take the train from Varese to Malpensa Aeroporto T1train train
    3. Fly from Milano Malpensa Airport (MXP) to Strasbourg International Airport (SXB)plane plane MXP - SXB
    4. Take the train from Strasbourg to Karlsruhe Hbftrain train
    6h 26m
    €66–304

  12. Train to Milano Malpensa Airport, fly to Zurich Airport, train

    1. Take the train from Varese to Malpensa Aeroporto T1train train
    2. Fly from Milano Malpensa Airport (MXP) to Zurich Airport (ZRH)plane plane MXP - ZRH
    3. Take the train from Zürich HB to Basel SBBtrain train
    4. Take the train from Basel SBB to Karlsruhe Hauptbahnhoftrain train
    8h 25m
    €131–364

Ispra to Karlsruhe by bus and train

Calendar100Weekly Services
Duration7h 52mAverage Duration
Ticket€48Cheapest Price
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Comparing Your Travel Options

Map of how to get from Ispra to Karlsruhe.ExpandLaunch map view
  • Distance: 512 km
  • Duration: 6h 11m

What companies run services between Ispra, Italy and Karlsruhe, Germany?

You can take a vehicle from Ispra to Karlsruhe Hauptbahnhof via Stresa and Basel SBB in around 6h 11m. Alternatively, FlixBus operates a bus from Como Grandate to Karlsruhe central train station 5 times a week. Tickets cost €45–75 and the journey takes 9h 5m.

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