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How to get fromIspra to Sienaby train, bus, car, plane, or train (Trenitalia)

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There are 6 ways to get from Ispra to Siena by train, bus, car, plane, or train (Trenitalia)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, bus via Florence

    best
    1. Take the train from Gavirate to Milano Bovisa Politecnicotrain train Re1 / ...
    2. Take the train from Milano Rogoredo to Firenze S.M.N.train train Fr
    3. Take the bus from Firenze Autostazione to Siena-Via Tozzibus bus 131
    6h 20m
    €44–86

  2. Train, bus

    cheapest
    1. Take the train from Varese to Rho Fiera Milanotrain train S5 / ...
    2. Take the bus from Milano, Autostazione Lampugnano to Sienabus bus N528 / ...
    8h 1m
    €39–84

  3. Drive  429.1 km

    1. Drive from Ispra to Sienacar car 429.1 km
    4h 25m
    €70–101

  4. Train, fly

    1. Take the train from Varese to Malpensa Aeroporto T1train train
    2. Fly from Milano Malpensa Airport (MXP) to Florence Peretola Airport (FLR)plane plane MXP - FLR
    3. Take the train from Firenze S.M.N. to Sienatrain train
    8h 47m
    €141–296

  5. Train

    1. Take the train from Varese to Rho Fiera Milanotrain train S5 / ...
    2. Take the train from Milano Rogoredo to Bologna centraletrain train
    3. Take the train from Bologna Centrale to Firenze S.M.N.train train Fr
    4. Take the train from Firenze S.M.N. to Sienatrain train Re
    6h 44m
    €54–125

  6. Bus

    1. Take the bus from Como to Florence Villa Constanza Bus Stationbus bus
    2. Take the bus from Florence Villa Constanza Bus Station to Sienabus bus 1518 / ...
    9h 12m
    €73–104

Ispra to Siena by bus and train

Calendar106Weekly Services
Duration6h 20mAverage Duration
Ticket€44Cheapest Price
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Comparing Your Travel Options

Map of how to get from Ispra to Siena.ExpandLaunch map view
  • Distance: 454 km
  • Duration: 6h 20m

What companies run services between Ispra, Italy and Siena, Italy?

You can take a bus from Ispra, Mazzini/Roma,distributore to Siena via Varese, Morosini,Stazione FS FN, Varese, Rho Fiera Milano, Milano Rogoredo, Bologna Centrale, and Firenze S.M.N. in around 6h 44m. Alternatively, you can take a bus from Ispra, Mazzini/Roma,distributore to Siena via Varese, Kennedy,Autostazione, Varese - Stazione FNM, Como - Stazione FNM, Como Stazione Lago, Como - S. Zenone, Como, and Florence Villa Constanza Bus Station in around 9h 12m.

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