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How to get fromIspra to Sienaby train (Trenitalia), train, bus, car, or plane

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There are 7 ways to get from Ispra to Siena by train (Trenitalia), train, bus, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Varese to Rho Fiera Milanotrain train S5 / ...
    2. Take the train from Milano Rogoredo to Bologna centraletrain train
    3. Take the train from Bologna Centrale to Firenze S.M.N.train train Fr
    4. Take the train from Firenze S.M.N. to Sienatrain train Re
    6h 41m
    €52–162

  2. Train, bus

    cheapest
    1. Take the train from Varese to Rho Fiera Milanotrain train S5 / ...
    2. Take the bus from Milano, Autostazione Lampugnano to Sienabus bus N528 / ...
    8h 2m
    €33–103

  3. Drive 429.1 km

    1. Drive from Ispra to Sienacar car 429.1 km
    4h 25m
    €67–97

  4. Train to Milano Malpensa Airport, fly, train

    1. Take the train from Varese to Malpensa Aeroporto T1train train
    2. Fly from Milano Malpensa Airport (MXP) to Florence Peretola Airport (FLR)plane plane MXP - FLR
    3. Take the train from Firenze S.M.N. to Sienatrain train
    8h 37m
    €107–284

  5. Train, bus via Florence

    1. Take the train from Varese to Rho Fiera Milanotrain train S5 / ...
    2. Take the train from Rho-Fiera Milano to Florence Santa Maria Novellatrain train
    3. Take the bus from Firenze Autostazione to Siena-Via Tozzibus bus 131
    6h 46m
    €49–137

  6. Bus

    1. Take the bus from Como to Florence Villa Constanza Bus Stationbus bus
    2. Take the bus from Florence Villa Constanza Bus Station to Sienabus bus N528 / ...
    9h 15m

  7. Train to Milan Linate Airport, fly, train

    1. Take the train from Varese to Milano Dateotrain train
    2. Fly from Milan Linate Airport (LIN) to Florence Peretola Airport (FLR)plane plane LIN - FLR
    3. Take the train from Firenze S.M.N. to Sienatrain train
    8h 39m
    €139–289

Ispra to Siena by bus and train

Calendar99Weekly Services
Duration6h 41mAverage Duration
Ticket€52Cheapest Price
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Questions & Answers

Map of how to get from Ispra to Siena.ExpandLaunch map view
  • Distance: 482.4 km
  • Duration: 6h 41m

What companies run services between Ispra, Italy and Siena, Italy?

You can take a bus from Ispra, Mazzini/Roma,distributore to Siena via Varese, Morosini,Stazione FS FN, Varese, Rho Fiera Milano, Milano Rogoredo, Bologna Centrale, and Firenze S.M.N. in around 6h 41m. Alternatively, you can take a bus from Ispra, Mazzini/Roma,distributore to Siena via Varese, Kennedy,Autostazione, Varese - Stazione FNM, Como - Stazione FNM, Como Stazione Lago, Como - S. Zenone, Como, and Florence Villa Constanza Bus Station in around 9h 15m.

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