There are 7 ways to get from Ispra to Siena by train (Trenitalia), bus, car, train, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train via Bologna
best- Take the train from Varese to Rho Fiera Milanotrain S5 / ...
- Take the train from Milano Rogoredo to Bologna centraletrain
- Take the train from Bologna Centrale to Firenze S.M.N.train Fr
- Take the train from Firenze S.M.N. to Sienatrain Re
6h 21m€52–162Train, bus
cheapest- Take the train from Varese to Rho Fiera Milanotrain S5 / ...
- Take the train from Rho-Fiera Milano to Florence Santa Maria Novellatrain
- Take the bus from Firenze Autostazione to Siena-Via Tozzibus 131
6h 46m€49–137Bus
- Take the bus from Como to Florence Villa Constanza Bus Stationbus
- Take the bus from Florence Villa Constanza Bus Station to Sienabus N528 / ...
9h 13mDrive 429.1 km
- Drive from Ispra to Sienacar 429.1 km
4h 25m€67–97Train to Milano Malpensa Airport, fly, train
- Take the train from Varese to Malpensa Aeroporto T1train
- Fly from Milano Malpensa Airport (MXP) to Florence Peretola Airport (FLR)plane MXP - FLR
- Take the train from Firenze S.M.N. to Sienatrain
8h 12m€107–264Train
- Take the train from Varese to Rho Fiera Milanotrain S5 / ...
- Take the train from Rho-Fiera Milano to Firenze S.M.N.train Fr
- Take the train from Firenze S.M.N. to Sienatrain Re
7h 11m€60–165Train to Milan Linate Airport, fly, train
- Take the train from Varese to Milano Dateotrain
- Fly from Milan Linate Airport (LIN) to Florence Peretola Airport (FLR)plane LIN - FLR
- Take the train from Firenze S.M.N. to Sienatrain
8h 14m€129–299
Ispra to Siena by bus and train
Questions & Answers
The cheapest way to get from Ispra to Siena is to train and bus which costs €45 - €140 and takes 6h 46m.
The fastest way to get from Ispra to Siena is to drive which takes 4h 25m and costs €65 - €100.
No, there is no direct bus from Ispra to Siena. However, there are services departing from Ispra, Mazzini/Roma,distributore and arriving at Siena via Varese - Stazione FNM, Como Stazione Lago, Como and Florence Villa Constanza Bus Station. The journey, including transfers, takes approximately 9h 13m.
No, there is no direct train from Ispra to Siena. However, there are services departing from Varese and arriving at Siena via Milano Rogoredo, Bologna Centrale and Firenze S.M.N.. The journey, including transfers, takes approximately 6h 21m.
The distance between Ispra and Siena is 482 km. The road distance is 429.1 km.
The best way to get from Ispra to Siena without a car is to train via Bologna which takes 6h 21m and costs €50 - €170.
It takes approximately 6h 21m to get from Ispra to Siena, including transfers.
Ispra to Siena bus services, operated by Onebus, depart from Como station.
Ispra to Siena train services, operated by Trenord, depart from Varese station.
The best way to get from Ispra to Siena is to train via Bologna which takes 6h 21m and costs €50 - €170. Alternatively, you can bus, which costs and takes 9h 13m.
What companies run services between Ispra, Italy and Siena, Italy?
You can take a bus from Ispra, Mazzini/Roma,distributore to Siena via Varese, Morosini,Stazione FS FN, Varese, Rho Fiera Milano, Milano Rogoredo, Bologna Centrale, and Firenze S.M.N. in around 6h 21m. Alternatively, you can take a bus from Ispra, Mazzini/Roma,distributore to Siena via Varese, Kennedy,Autostazione, Varese - Stazione FNM, Como - Stazione FNM, Como Stazione Lago, Como - S. Zenone, Como, and Florence Villa Constanza Bus Station in around 9h 13m.
- Website
- ita-airways.com
Flights from Milano Malpensa Airport to Florence Peretola Airport via Zurich
- Ave. Duration
- 3h 43m
- When
- Every day
- Estimated price
- €90–300
Flights from Milano Malpensa Airport to Florence Peretola Airport via Munich
- Ave. Duration
- 3h 52m
- When
- Every day
- Estimated price
- €150–550
Flights from Milano Malpensa Airport to Florence Peretola Airport via Rome
- Ave. Duration
- 3h 40m
- When
- Saturday
- Estimated price
- €130–440
Flights from Milan Linate Airport to Florence Peretola Airport via Rome
- Ave. Duration
- 3h 20m
- When
- Every day
- Estimated price
- €140–260
Flights from Milan Linate Airport to Florence Peretola Airport via Vienna
- Ave. Duration
- 3h 40m
- When
- Every day
- Estimated price
- €100–390
Flights from Milan Linate Airport to Florence Peretola Airport via Frankfurt
- Ave. Duration
- 4h 10m
- When
- Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €190–700
Flights from Milan Linate Airport to Florence Peretola Airport via Munich
- Ave. Duration
- 5h 10m
- When
- Monday to Saturday
- Estimated price
- €180–650
- Website
- swiss.com
Flights from Milano Malpensa Airport to Florence Peretola Airport via Zurich
- Ave. Duration
- 3h 43m
- When
- Every day
- Estimated price
- €90–300
Flights from Milano Malpensa Airport to Florence Peretola Airport via Rome
- Ave. Duration
- 3h 40m
- When
- Saturday
- Estimated price
- €130–440
- Website
- lufthansa.com
Flights from Milano Malpensa Airport to Florence Peretola Airport via Munich
- Ave. Duration
- 3h 52m
- When
- Every day
- Estimated price
- €150–550
Flights from Milano Malpensa Airport to Florence Peretola Airport via Rome
- Ave. Duration
- 3h 40m
- When
- Saturday
- Estimated price
- €130–440
Flights from Milan Linate Airport to Florence Peretola Airport via Frankfurt
- Ave. Duration
- 4h 10m
- When
- Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €190–700
Flights from Milan Linate Airport to Florence Peretola Airport via Munich
- Ave. Duration
- 5h 10m
- When
- Monday to Saturday
- Estimated price
- €180–650
- Website
- airdolomiti.it
Flights from Milano Malpensa Airport to Florence Peretola Airport via Munich
- Ave. Duration
- 3h 52m
- When
- Every day
- Estimated price
- €150–550
Flights from Milan Linate Airport to Florence Peretola Airport via Frankfurt
- Ave. Duration
- 4h 10m
- When
- Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €190–700
- Website
- austrian.com
Flights from Milano Malpensa Airport to Florence Peretola Airport via Rome
- Ave. Duration
- 3h 40m
- When
- Saturday
- Estimated price
- €130–440
Flights from Milan Linate Airport to Florence Peretola Airport via Rome
- Ave. Duration
- 3h 40m
- When
- Every day
- Estimated price
- €140–260
Flights from Milan Linate Airport to Florence Peretola Airport via Vienna
- Ave. Duration
- 3h 40m
- When
- Every day
- Estimated price
- €100–390
- Website
- polarair.ru
Flights from Milan Linate Airport to Florence Peretola Airport via Elba Island
- Ave. Duration
- 2h 20m
- When
- Sunday
- Estimated price
- €40–550
- Website
- flexflight.dk
Flights from Milan Linate Airport to Florence Peretola Airport via Elba Island
- Ave. Duration
- 2h 20m
- When
- Sunday
- Estimated price
- €40–550
- Phone
- +39 02 7249 4494
- [email protected]
- Website
- Trenord
Train from Varese to Rho Fiera Milano
- Ave. Duration
- 58 min
- Frequency
- Every 30 minutes
- Estimated price
- €4–6
- Website
- Trenord
Train from Varese to Malpensa Aeroporto T1
- Ave. Duration
- 41 min
- Frequency
- Hourly
- Estimated price
- €4–5
- Website
- Trenord
Train from Varese to Rho Fiera Milano
- Ave. Duration
- 58 min
- Frequency
- Every 30 minutes
- Estimated price
- €4–6
- Website
- Trenord
Train from Varese to Rho Fiera Milano
- Ave. Duration
- 58 min
- Frequency
- Every 30 minutes
- Estimated price
- €4–6
- Website
- Trenord
Train from Varese to Milano Dateo
- Ave. Duration
- 1h 21m
- Frequency
- Hourly
- Estimated price
- €5–7
- Website
- Trenord
Train from Varese to Rho Fiera Milano
- Ave. Duration
- 37 min
- Frequency
- 4 times a week
- Estimated price
- €17–55
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Varese to Malpensa Aeroporto T1
- Ave. Duration
- 41 min
- Frequency
- Hourly
- Estimated price
- €14–45
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Varese to Rho Fiera Milano
- Ave. Duration
- 37 min
- Frequency
- 4 times a week
- Estimated price
- €17–55
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Varese to Rho Fiera Milano
- Ave. Duration
- 37 min
- Frequency
- 4 times a week
- Estimated price
- €17–55
- Website
- Swiss Federal Railways (SBB CFF FFS)
- Phone
- +39 06 8937 1892
- Website
- Italo Treno
Train from Milano Rogoredo to Bologna centrale
- Ave. Duration
- 1h 22m
- Frequency
- Hourly
- Estimated price
- €28–60
- Website
- Italo Treno
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 46 min
- Frequency
- 5 times a day
- Estimated price
- €11–23
- Website
- Italo Treno
Train from Rho-Fiera Milano to Florence Santa Maria Novella
- Ave. Duration
- 2h 15m
- Frequency
- Every 3 hours
- Estimated price
- €40–80
- Website
- Italo Treno
- Phone
- +39 06 68475475
- Website
- Trenitalia Frecce
Train from Milano Rogoredo to Bologna centrale
- Ave. Duration
- 1h 41m
- Frequency
- Every 3 hours
- Estimated price
- €30–65
- Schedules at
- Trenitalia Frecce
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 37 min
- Frequency
- Every 15 minutes
- Estimated price
- €13–27
- Schedules at
- Trenitalia Frecce
Train from Rho-Fiera Milano to Firenze S.M.N.
- Ave. Duration
- 2h 22m
- Frequency
- Every 3 hours
- Estimated price
- €45–95
- Schedules at
- Trenitalia Frecce
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 35m
- Frequency
- 4 times a day
- Estimated price
- €11–19
- Website
- Trenitalia
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–19
- Website
- Trenitalia
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–19
- Website
- Trenitalia
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–19
- Website
- Trenitalia
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–19
- Website
- Trenitalia
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 16m
- Frequency
- Twice daily
- Estimated price
- €9–21
- Website
- Trenitalia Intercity
- Phone
- +39 0362 185 0590
- [email protected]
- Website
- Onebus
Bus from Como to Florence Villa Constanza Bus Station
- Ave. Duration
- 3h 7m
- Frequency
- Once a week
- Website
- Onebus
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Florence Villa Constanza Bus Station to Siena
- Ave. Duration
- 50 min
- Frequency
- Every 2 hours
- Estimated price
- €5–9
- Website
- Flixbus
- Phone
- +3 318 576 2228
- Website
- BlaBlaCar Bus
Bus from Florence Villa Constanza Bus Station to Siena
- Ave. Duration
- 1h
- Frequency
- Once daily
- Estimated price
- €5–11
- Website
- BlaBlaCar Bus
- Phone
- +39 800 142 424
- [email protected]
- Website
- Autolinee Toscane
Bus from Firenze Autostazione to Siena-Via Tozzi
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- €5–6
- Website
- Autolinee Toscane
- Schedules at
- Autolinee Toscane
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More Questions & Answers
Ispra to Siena bus services, operated by Onebus, arrive at Florence Villa Constanza Bus Station.
Ispra to Siena train services, operated by Trenord, arrive at Rho Fiera Milano station.
Yes, the driving distance between Ispra to Siena is 429 km. It takes approximately 4h 25m to drive from Ispra to Siena.
There are 2528+ hotels available in Siena.






































