There are 6 ways to get from Ispra to Siena by train (Trenitalia), train, bus, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train
best- Take the train from Gavirate to Milano Bovisa Politecnicotrain Re1 / ...
- Take the train from Milano Rogoredo to Firenze S.M.N.train Fr
- Take the train from Firenze S.M.N. to Sienatrain Re
6h 19m€47–116Train, bus
cheapest- Take the train from Varese to Rho Fiera Milanotrain S5 / ...
- Take the bus from Milano, Autostazione Lampugnano to Sienabus N528 / ...
8h 2m€32–96Drive 429.1 km
- Drive from Ispra to Sienacar 429.1 km
4h 25m€68–98Train to Milano Malpensa Airport, fly, train
- Take the train from Varese to Malpensa Aeroporto T1train
- Fly from Milano Malpensa Airport (MXP) to Florence Peretola Airport (FLR)plane MXP - FLR
- Take the train from Firenze S.M.N. to Sienatrain
8h 12m€107–283Bus
- Take the bus from Como to Florence Villa Constanza Bus Stationbus
- Take the bus from Florence Villa Constanza Bus Station to Sienabus N528 / ...
9h 15m€69–99Train to Milan Linate Airport, fly, train
- Take the train from Gavirate to Milano Cadornatrain
- Fly from Milan Linate Airport (LIN) to Florence Peretola Airport (FLR)plane LIN - FLR
- Take the train from Firenze S.M.N. to Sienatrain
7h 56m€130–292
Ispra to Siena by bus and train
Questions & Answers
The cheapest way to get from Ispra to Siena is to train and bus which costs €30 - €100 and takes 8h 2m.
The fastest way to get from Ispra to Siena is to drive which takes 4h 25m and costs €65 - €100.
No, there is no direct bus from Ispra to Siena. However, there are services departing from Ispra, Mazzini/Roma,distributore and arriving at Siena via Varese - Stazione FNM, Como Stazione Lago, Como and Florence Villa Constanza Bus Station. The journey, including transfers, takes approximately 9h 15m.
No, there is no direct train from Ispra to Siena. However, there are services departing from Gavirate and arriving at Siena via Milano Bovisa Politecnico, Milano Rogoredo and Firenze S.M.N.. The journey, including transfers, takes approximately 6h 19m.
The distance between Ispra and Siena is 476 km. The road distance is 429.1 km.
The best way to get from Ispra to Siena without a car is to train which takes 6h 19m and costs €45 - €120.
It takes approximately 6h 19m to get from Ispra to Siena, including transfers.
Ispra to Siena bus services, operated by Onebus, depart from Como station.
Ispra to Siena train services, operated by Trenord, depart from Gavirate station.
The best way to get from Ispra to Siena is to train which takes 6h 19m and costs €45 - €120. Alternatively, you can bus, which costs €65 - €100 and takes 9h 15m.
What companies run services between Ispra, Italy and Siena, Italy?
You can take a bus from Ispra, Mazzini 322,circolo to Siena via Gavirate, Mazza 2 fr. Stazione FN,centro, Gavirate, Milano Bovisa Politecnico, Milano Rogoredo, and Firenze S.M.N. in around 6h 19m. Alternatively, you can take a bus from Ispra, Mazzini/Roma,distributore to Siena via Varese, Kennedy,Autostazione, Varese - Stazione FNM, Como - Stazione FNM, Como Stazione Lago, Como - S. Zenone, Como, and Florence Villa Constanza Bus Station in around 9h 15m.
- Website
- ita-airways.com
Flights from Milano Malpensa Airport to Florence Peretola Airport via Zurich
- Ave. Duration
- 3h 43m
- When
- Every day
- Estimated price
- €90–310
Flights from Milano Malpensa Airport to Florence Peretola Airport via Munich
- Ave. Duration
- 3h 52m
- When
- Every day
- Estimated price
- €140–550
Flights from Milano Malpensa Airport to Florence Peretola Airport via Rome
- Ave. Duration
- 3h 40m
- When
- Saturday
- Estimated price
- €130–400
Flights from Milan Linate Airport to Florence Peretola Airport via Rome
- Ave. Duration
- 3h 20m
- When
- Every day
- Estimated price
- €140–250
Flights from Milan Linate Airport to Florence Peretola Airport via Vienna
- Ave. Duration
- 3h 40m
- When
- Every day
- Estimated price
- €100–390
Flights from Milan Linate Airport to Florence Peretola Airport via Frankfurt
- Ave. Duration
- 4h 10m
- When
- Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €170–700
Flights from Milan Linate Airport to Florence Peretola Airport via Munich
- Ave. Duration
- 5h 10m
- When
- Monday to Saturday
- Estimated price
- €170–650
- Phone
- +39 02 7249 4494
- [email protected]
- Website
- Trenord
Train from Gavirate to Milano Bovisa Politecnico
- Ave. Duration
- 1h 3m
- Frequency
- Hourly
- Estimated price
- €5–6
- Website
- Trenord
Train from Varese to Rho Fiera Milano
- Ave. Duration
- 58 min
- Frequency
- Every 30 minutes
- Estimated price
- €4–6
- Website
- Trenord
Train from Varese to Malpensa Aeroporto T1
- Ave. Duration
- 41 min
- Frequency
- Hourly
- Estimated price
- €4–5
- Website
- Trenord
Train from Gavirate to Milano Cadorna
- Ave. Duration
- 1h 12m
- Frequency
- Hourly
- Estimated price
- €5–7
- Website
- Trenord
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Milano, Autostazione Lampugnano to Siena
- Ave. Duration
- 4h 55m
- Frequency
- Every 4 hours
- Estimated price
- €27–45
- Website
- Flixbus
Bus from Florence Villa Constanza Bus Station to Siena
- Ave. Duration
- 50 min
- Frequency
- Every 3 hours
- Estimated price
- €5–8
- Website
- Flixbus
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More Questions & Answers
Ispra to Siena bus services, operated by Onebus, arrive at Florence Villa Constanza Bus Station.
Ispra to Siena train services, operated by Trenord, arrive at Milano Bovisa Politecnico station.
Yes, the driving distance between Ispra to Siena is 429 km. It takes approximately 4h 25m to drive from Ispra to Siena.
There are 2519+ hotels available in Siena.








