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How to get fromIstanbul to Mesopotamíaby bus, car, plane, or train

Find Transport to Mesopotamía

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There are 10 ways to get from Istanbul to Mesopotamía by bus, car, plane, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Istanbul Esenler Otogari to Thessaloniki Macedonia KTEL Bus Stationbus bus Arda-Tur
    2. Take the bus from Thessaloniki Macedonia KTEL Bus Station to Kastoriabus bus
    14h 13m
    €81–110

  2. Bus #2

    cheapest
    1. Take the bus from Istanbul to Thessaloniki Macedonia KTEL Bus Stationbus bus
    2. Take the bus from Thessaloniki Macedonia KTEL Bus Station to Kastoriabus bus
    14h 13m
    €58–72

  3. Drive 780 km

    1. Drive from Istanbul to Mesopotamíacar car 780 km
    8h 4m
    €142–205

  4. Fly Istanbul to Thessaloniki Airport Makedonia, bus

    1. Fly from Istanbul (IST) to Thessaloniki Airport Makedonia (SKG)plane plane IST - SKG
    2. Take the bus from Thessaloniki Macedonia KTEL Bus Station to Kastoriabus bus
    9h 43m
    €119–237

  5. Bus via Kapshtice

    1. Take the bus from Istanbul Otogari to Thessalonikibus bus
    2. Take the bus from Thessaloníki to Kapshticebus bus
    18h 41m

  6. Fly Istanbul to Ohrid Airport, drive

    1. Fly from Istanbul (IST) to Ohrid Airport (OHD)plane plane IST - OHD
    2. Drive from Ohrid Airport (OHD) to Mesopotamíacar car
    7h 6m
    €134–337

  7. Fly Istanbul to Tirana International Airport Nënë Tereza, bus

    1. Fly from Istanbul (IST) to Tirana International Airport Nënë Tereza (TIA)plane plane IST - TIA
    2. Take the bus from Tirana to Kastoriabus bus
    10h 19m

  8. Fly Istanbul Sabiha Gökçen International Airport to Tirana International Airport Nënë Tereza, bus

    1. Fly from Istanbul Sabiha Gökçen International Airport (SAW) to Tirana International Airport Nënë Tereza (TIA)plane plane SAW - TIA
    2. Take the bus from Tirana to Kastoriabus bus
    10h 39m

  9. Fly Istanbul Sabiha Gökçen International Airport to Skopje International Airport, train, drive

    1. Fly from Istanbul Sabiha Gökçen International Airport (SAW) to Skopje International Airport (SKP)plane plane SAW - SKP
    2. Take the train from Skopje to Zabenitrain train
    3. Drive from Zabeni to Mesopotamíacar car
    13h 50m
    €80–375

  10. Fly Istanbul to Skopje International Airport, train, drive

    1. Fly from Istanbul (IST) to Skopje International Airport (SKP)plane plane IST - SKP
    2. Take the train from Skopje to Zabenitrain train
    3. Drive from Zabeni to Mesopotamíacar car
    13h 35m
    €140–425

Istanbul (IST) to Thessaloniki Airport Makedonia (SKG) flights

Calendar22Weekly Planes
Duration2h 12mAverage Duration
Ticket€78Cheapest Price
See schedules

Questions & Answers

Map of how to get from Istanbul to Mesopotamía.ExpandLaunch map view
  • Distance: 879.6 km
  • Duration: 14h 13m

What companies run services between Istanbul, Turkey and Mesopotamía, Greece?

You can take a bus from Istanbul Esenler Otogari to Mesopotamía via Thessaloniki Macedonia KTEL Bus Station and Kastoria in around 14h 13m.

Airlines
Train operators
Bus operators

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