There are 8 ways to get from Istanbul to Mesopotamía by bus, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Istanbul Esenler Otogari to Thessaloniki Macedonia KTEL Bus Stationbus Arda-Tur
- Take the bus from Thessaloniki Macedonia KTEL Bus Station to Kastoriabus
14h 13m€122–125Bus #2
cheapest- Take the bus from Istanbul to Thessaloniki Macedonia KTEL Bus Stationbus
- Take the bus from Thessaloniki Macedonia KTEL Bus Station to Kastoriabus
14h 13m€61–74Drive 780 km
- Drive from Istanbul to Mesopotamíacar 780 km
8h 4m€141–204Fly Istanbul to Thessaloniki Airport Makedonia, bus
- Fly from Istanbul (IST) to Thessaloniki Airport Makedonia (SKG)plane IST - SKG
- Take the bus from Thessaloniki Macedonia KTEL Bus Station to Kastoriabus
9h 43m€122–250Bus via Kapshtice
- Take the bus from Istanbul Otogari to Thessalonikibus
- Take the bus from Thessaloníki to Kapshticebus
18h 41mFly Istanbul to Ohrid Airport, drive
- Fly from Istanbul (IST) to Ohrid Airport (OHD)plane IST - OHD
- Drive from Ohrid Airport (OHD) to Mesopotamíacar
7h 6m€134–337Fly Istanbul to Tirana International Airport Nënë Tereza, bus
- Fly from Istanbul (IST) to Tirana International Airport Nënë Tereza (TIA)plane IST - TIA
- Take the bus from Tirana to Kastoriabus
10h 19mFly Istanbul Sabiha Gökçen International Airport to Tirana International Airport Nënë Tereza, bus
- Fly from Istanbul Sabiha Gökçen International Airport (SAW) to Tirana International Airport Nënë Tereza (TIA)plane SAW - TIA
- Take the bus from Tirana to Kastoriabus
10h 39m
Istanbul (IST) to Thessaloniki Airport Makedonia (SKG) flights
Questions & Answers
The cheapest way to get from Istanbul to Mesopotamía is to bus which costs €60 - €75 and takes 14h 13m.
The fastest way to get from Istanbul to Mesopotamía is to fly and drive which takes 7h 6m and costs €130 - €340.
No, there is no direct bus from Istanbul to Mesopotamía. However, there are services departing from Istanbul Esenler Otogari and arriving at Kastoria via Thessaloniki Macedonia KTEL Bus Station. The journey, including transfers, takes approximately 14h 13m.
The distance between Istanbul and Mesopotamía is 880 km. The road distance is 780 km.
The best way to get from Istanbul to Mesopotamía without a car is to bus which takes 14h 13m and costs €121 - €125.
It takes approximately 14h 13m to get from Istanbul to Mesopotamía, including transfers.
Istanbul to Mesopotamía bus services, operated by Arda Tur, depart from Istanbul Esenler Otogari station.
Istanbul to Mesopotamía bus services, operated by Arda Tur, arrive at Thessaloniki Macedonia KTEL Bus Station.
Yes, the driving distance between Istanbul to Mesopotamía is 780 km. It takes approximately 8h 4m to drive from Istanbul to Mesopotamía.
There are 249+ hotels available in Mesopotamía.
What companies run services between Istanbul, Turkey and Mesopotamía, Greece?
You can take a bus from Istanbul Esenler Otogari to Mesopotamía via Thessaloniki Macedonia KTEL Bus Station and Kastoria in around 14h 13m.
- Website
- en.aegeanair.com
Flights from Istanbul to Thessaloniki Airport Makedonia
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- €85–330
Flights from Istanbul to Thessaloniki Airport Makedonia via Athens
- Ave. Duration
- 3h 25m
- When
- Every day
- Estimated price
- €85–210
Flights from Istanbul to Tirana International Airport Nënë Tereza via Athens
- Ave. Duration
- 3h 55m
- When
- Every day
- Estimated price
- €90–270
- Website
- turkishairlines.com
Flights from Istanbul to Thessaloniki Airport Makedonia
- Ave. Duration
- 1h 22m
- When
- Every day
- Estimated price
- €95–330
Flights from Istanbul to Ohrid Airport
- Ave. Duration
- 1h 37m
- When
- Tuesday, Friday, Thursday, and Sunday
- Estimated price
- €110–290
Flights from Istanbul to Tirana International Airport Nënë Tereza
- Ave. Duration
- 1h 42m
- When
- Every day
- Estimated price
- €75–190
- Website
- flypgs.com
Flights from Istanbul Sabiha Gökçen International Airport to Tirana International Airport Nënë Tereza
- Ave. Duration
- 1h 45m
- When
- Every day
- Estimated price
- €35–220
- Website
- ajet.com
Flights from Istanbul Sabiha Gökçen International Airport to Tirana International Airport Nënë Tereza
- Ave. Duration
- 1h 45m
- When
- Every day
- Estimated price
- €55–170
- Phone
- +359 700 20 544
- Website
- Arda Tur
Bus from Istanbul Esenler Otogari to Thessaloniki Macedonia KTEL Bus Station
- Ave. Duration
- 10h
- Frequency
- Twice daily
- Estimated price
- €89
- Website
- Arda Tur
- [email protected]
- Website
- ktel-kastorias.gr
Bus from Thessaloniki Macedonia KTEL Bus Station to Kastoria
- Ave. Duration
- 3h
- Frequency
- 5 times a day
- Estimated price
- €20
- Schedules at
- ktel-kastorias.gr
Bus from Thessaloniki Macedonia KTEL Bus Station to Kastoria
- Ave. Duration
- 3h
- Frequency
- 5 times a day
- Estimated price
- €20
- Schedules at
- ktel-kastorias.gr
Bus from Thessaloniki Macedonia KTEL Bus Station to Kastoria
- Ave. Duration
- 3h
- Frequency
- 5 times a day
- Estimated price
- €20
- Schedules at
- ktel-kastorias.gr
- Phone
- +90 212 658 18 51
- [email protected]
- Website
- Alpar Turizm
Bus from Istanbul to Thessaloniki Macedonia KTEL Bus Station
- Ave. Duration
- 10h
- Frequency
- Once daily
- Estimated price
- €27–40
- Website
- Alpar Turizm
- Phone
- 0850 222 34 55
- Website
- MetroTurizm
Bus from Istanbul Otogari to Thessaloniki
- Ave. Duration
- 11h 45m
- Frequency
- Once daily
- Estimated price
- €30–45
- Website
- MetroTurizm
- Standard
- €30–45
- Phone
- +355 67 604 2191
- Website
- facebook.com
Bus from Thessaloníki to Kapshtice
- Ave. Duration
- 5h 30m
- Frequency
- Once daily
- Schedules at
- autobus.al
- Phone
- +355 699 605501
- [email protected]
- Website
- facebook.com
Bus from Tirana to Kastoria
- Ave. Duration
- 2h 57m
- Frequency
- Once daily
- Schedules at
- facebook.com
Bus from Tirana to Kastoria
- Ave. Duration
- 2h 57m
- Frequency
- Once daily
- Schedules at
- facebook.com
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